Patents Assigned to INSTITUTE OF ORGANIC CHEMISTRY & BIOCHEMISTRY
  • Use of chiral 2-(phosphonomethoxy)propyl guanines as antiviral agents
    Patent number: 5302585
    Abstract: The present invention provides chiral nucleotide analogs having the Formulas I and II ##STR1## and pharmaceutically acceptable salts and solvates thereof, and their pharmaceutical compositions for use in the treatment of viral infections, especially those caused by human immunodeficiency virus (HIV).
    Type: Grant
    Filed: July 22, 1992
    Date of Patent: April 12, 1994
    Assignees: Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic, Rega Stichting v.z.w.
    Inventors: Kuo-Long Yu, Joanne J. Bronson, John C. Martin