Patents Assigned to Institute of Organic Chemistry POS
  • Compositions and methods for tagging ribonucleic acids
    Patent number: 11155821
    Abstract: This invention relates to the field of ribonucleic acid (RNA) regulation of intracellular activity. In particular, the invention relates to compositions and methods of identifying and tracking specific intracellular RNAs. For example, a fluorescently tagged RNA probe may be tracked by in vivo live imaging throughout its intracellular lifetime in order to determine its purpose and identify regulatory targets to modify its effects. Alternatively, an RNA probe may carry a therapeutic payload for treatment of medical condition or disorder.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: October 26, 2021
    Assignees: The Regents of the University of Colorado, a body corporate, Institute of Organic Chemistry POS
    Inventors: Amy E. Palmer, Esther Braselmann, Robert T. Batey, Dorota Gryko