Patents Assigned to INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY SCIENCES, PLA
  • SYNTHESIS OF TIMOSAPONIN BII
    Publication number: 20110054156
    Abstract: The invention provides a synthetic route from sarsasapogenin to timosaponin BII and related compounds. A diketone intermediate is provided, which can advantageously be used for in situ assembly of complex sugar moieties of the desired glycone end product. The diketone compound is then selectively reduced using a borohydride reducing agent to form the desired end product, certain of the end products and intermediates are novel compounds perse.
    Type: Application
    Filed: April 30, 2008
    Publication date: March 3, 2011
    Applicant: INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY SCIENCES, PLA
    Inventors: Shuihong Cheng, Yuguo Du, Baiping Ma, Lu Li, Yang Zhao