Patents Assigned to INSTITUTE
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Patent number: 12006498Abstract: In the present specification, on the basis of the correlation between prospero homeobox protein 1 (PROX1) and telomerase reverse transcriptase (TERT), a composition for regulating expression of TERT, a method for screening a TERT expression regulator, a composition for diagnosing a TERT expression status, a diagnostic kit, a method for providing information for diagnosis, or a method for providing information for cancer diagnosis are disclosed. Specifically, in one aspect, the PROX1 of the present disclosure may bind to a TERT promoter, in particular a mutant TERT promoter in which base substitution occurs at the ?124 or ?146 bp position to regulate the expression of TERT, and the expression of TERT in non-hepatitis B virus-associated liver cancer can be inhibited specifically among liver cancers.Type: GrantFiled: October 19, 2018Date of Patent: June 11, 2024Assignees: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITYInventors: Sang Hoon Jung, Young-Joo Kim, Dae-geun Song, Young Nyun Park, Jeong Eun Yoo, Hyung Jin Rhee, Youngsic Jeon
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Patent number: 12006310Abstract: The present invention relates to the technical field of natural medicines, and in particular to a triterpenoid compound with an effect of improving glucose and lipid metabolism disorders, and preparation and application thereof. A novel triterpenoid compound was obtained by separation from Momordica charantia L. for the first time in the present invention. Studies on a mouse primary hepatocyte model and a 3T3-L1 preadipocyte model show that the novel triterpenoid compound in the present invention has activity of regulating glucose and lipid metabolism, and after combination with known triterpenoid compound Momordicoside G, the activity of regulating glucose and lipid metabolism is significantly higher than that of a single compound at the same dose, indicating that the novel triterpenoid compound and a complex thereof in the present invention can be used to improve glucose and lipid metabolism disorders and provide a new way for diabetes treatment.Type: GrantFiled: July 1, 2022Date of Patent: June 11, 2024Assignee: SERICULTURAL & AGRI-FOOD RESEARCH INSTITUTE GUANGDONG ACADEMY OF AGRICULTERAL SCIENCESInventors: Mingwei Zhang, Yuanyuan Deng, Guang Liu, Yan Zhang, Zhencheng Wei, Pengfei Zhou, Ping Li, Zhihao Zhao, Xuchao Jia, Xiaojun Tang
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Patent number: 12010466Abstract: A visual recognition based method for projecting patterned light includes: projecting a calibration image onto a projection screen by a projection module; capturing the calibration image by an image-capturing module to obtain a calibration information between the projection module and the image-capturing module; capturing an object by the image-capturing module to obtain a to-be-recognized image of the object; detecting the object in the to-be-recognized image and acquiring a plurality of feature points associated with a plurality of feature areas of the object in the to-be-recognized image; retrieving a plurality of target feature points corresponding to a target object from the feature points; obtaining a projection coordinate of the target feature points\ according to the calibration information and providing the projection coordinate to the projection module; and projecting a projection pattern with shape corresponding to the target object onto the object by the projection module according to the projectiType: GrantFiled: December 22, 2021Date of Patent: June 11, 2024Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Cheng-Han Tsai, Kuo-Feng Hung
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Patent number: 12005093Abstract: The present invention relates to the preparation technical field of traditional Chinese medicine and more particularly, to a traditional Chinese medicine eye drops and the preparation method thereof. The traditional Chinese medicine components of the traditional Chinese medicine eye drops provided by the embodiments of the invention comprise: ginseng Radix et rhizoma of 5-10 wt %, scrophulariae Radix of 15-20 wt %, xanthii Fructus of 5-10 wt %, bovis Calculus sativus of 5-10 wt %, Carthami flos of 5-10 wt %, borneolum of 5-10 wt %, senecionis scandentis herba of 25-35 wt %, fibraureae caulis of 5-15 wt % and motherwort fruit of 5-10 wt %.Type: GrantFiled: August 11, 2022Date of Patent: June 11, 2024Assignee: HONG KONG CHINESE MEDICINE OPHTHALMOLOGY INSTITUTE LIMITEDInventor: See Tung Kwan
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Patent number: 12010789Abstract: An accelerating cavity includes an electrically conductive cylindrical housing and a plurality of cells that are made of a dielectric material and have openings in respective central portions of the cells through which charged particles are allowed to pass. The cells are arranged inside the housing while being aligned in the axial direction of the central axis of the housing, and sandwiched by the housing in the axial direction of the central axis to be immobilized. The housing has grooves provided on portions thereof that support the respective cells and each having a depth that is one fourth of the wavelength of radio frequency waves for the acceleration mode that propagate through the cells.Type: GrantFiled: May 15, 2020Date of Patent: June 11, 2024Assignees: MITSUBISHI HEAVY INDUSTRIES MACHINERY SYSTEMS, LTD., INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION HIGH ENERGY ACCELERATOR RESEARCH ORGANIZATIONInventors: Shingo Mori, Mitsuhiro Yoshida, Nobuyuki Shigeoka
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Patent number: 12010235Abstract: An apparatus is one of a plurality of apparatuses that participate in multi-party computation and the apparatus implements a protocol to perform zero-knowledge proof in secret-distribution-based multi-party computation. The apparatus includes an acquisition unit that acquires a share of data related to a matter to be certified, and an output unit that outputs an output share obtained as a result of performing calculation according to the protocol using the acquired share as an input. Verification in zero-knowledge proof can be performed using output shares collected from the plurality of apparatuses participating in the multi-party computation.Type: GrantFiled: September 3, 2021Date of Patent: June 11, 2024Assignee: NOMURA RESEARCH INSTITUTE, LTD.Inventor: Masashi Kawaguchi
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Patent number: 12009761Abstract: A triboelectric generator is disclosed. The triboelectric generator according to an embodiment of the present disclosure includes a flexible electrode part comprising a first and a second dielectric layer, and at least one metal layer; and a fixed electrode part spaced apart from both sides of the flexible electrode part, and comprising a first and a second electrode connected to each other, wherein the flexible electrode part generates triboelectrification based on contact and non-contact by a fluid flow, and an electric charge moves through the metal layer, thereby effectively moving electric charges generated by triboelectrification, and increasing the friction frequency to enhance power generation efficiency.Type: GrantFiled: March 5, 2020Date of Patent: June 11, 2024Assignees: LG ELECTRONICS INC., GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Byungsoo Oh, Yoseop Shin, Sungjun Cho, Gunyoung Jung
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Patent number: 12008688Abstract: A method for processing breast tomosynthesis images includes: obtaining multiple breast images, performing binarization operation and pooling operation to at least one marked breast image to obtain a lesion mask; training a convolutional neural network (CNN) according to the breast images and the lesion mask; obtaining multiple cropped images from the breast images of different layers according to a particular two-dimensional position, and inputting each cropped image into the CNN to obtain cropped heat maps; inputting the cropped heat maps into a recurrent neural network (RNN) in an order of the levels to obtain output heat maps, and combining the output heat maps to obtain a integrated heat map, and training the RNN according to the integrated heat map and the lesion mask.Type: GrantFiled: August 30, 2021Date of Patent: June 11, 2024Assignee: INSTITUTE FOR INFORMATION INDUSTRYInventors: Kai-Hsuan Chan, Yao-Min Huang
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Patent number: 12010693Abstract: A base station in a wireless communication system is provided. Each base station for wireless communication comprises: a communication module; and a processor. The processor is configured to determine the number of dynamic slot format information (SFI) bits based on a maximum value of a slot format combination index which can be indicated by dynamic SFI transmitted to a terminal, and monitor a physical downlink control channel (PDCCH) including the dynamic SFI based on the number of the dynamic SFI bits. The slot format combination index identifies a slot format combination configured for the terminal. The slot format combination indicates a type of a symbol included in one or more slots, and the type of the symbol is one among a downlink symbol, an uplink symbol, and a flexible symbol.Type: GrantFiled: August 20, 2019Date of Patent: June 11, 2024Assignee: WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC.Inventors: Kyungjun Choi, Minseok Noh, Jinsam Kwak
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Patent number: 12005724Abstract: In a leveling unit for imprinting and an imprint apparatus having the leveling unit, the leveling unit includes a base plate, a moving plate and a plurality of link parts. The moving plate is spaced apart from the base plate, and has a reference plane heading for an opposite direction of the base plate. The plurality of link parts connects the base plate with the moving plate, is spaced apart from each other by a predetermined distance along a circumferential direction with respect to a center of the reference plane, and is elastically and independently transformed by a pressing force applied to the reference plane to adjust an inclination of the moving plate.Type: GrantFiled: July 20, 2020Date of Patent: June 11, 2024Assignee: KOREA INSTITUTE OF MACHINERY & MATERIALSInventors: Kee-Bong Choi, Jae-Jong Lee, Geehong Kim, Hyungjun Lim, Soongeun Kwon, Junhyoung Ahn
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Patent number: 12005393Abstract: Disclosed is a flue gas low-temperature adsorption denitration system and process. The system includes a booster fan, a cold energy recoverer, a flue gas cooling system, a flue gas switching valve, and two denitration adsorption towers. An inlet of the booster fan is in communication with an inlet flue gas pipeline. The booster fan, the cold energy recoverer, the flue gas cooling system, the flue gas switching valve, and the denitration adsorption towers are sequentially communicated. An outlet of the flue gas switching valve is in communication with each of the two second denitration adsorption towers. Flue gas outlets of the two denitration adsorption towers are in communication with a flue gas manifold. The flue gas manifold is communicated with the cold quantity recoverer. Two denitration adsorption towers take turns to carry out denitration and regeneration processes, so that continuous denitration operations of the system can be achieved.Type: GrantFiled: April 25, 2021Date of Patent: June 11, 2024Assignee: HUANENG CLEAN ENERGY RESEARCH INSTITUTEInventors: Shiqing Wang, Qixiang Fan, Shisen Xu, Shiwang Gao, Shaomin Wang, He Zhao, Minhua Jiang, Ping Xiao, Bin Huang, Hongwei Niu, Jinyi Wang, Lianbo Liu
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Patent number: 12008906Abstract: A method of blind spot detection is provided. The method of blind spot detection is used for a vehicle including a first vehicle body and a second vehicle body dragged by the first vehicle body. The method of blind spot detection comprises the following steps: obtaining a turning angle information of the second vehicle body relative to the first vehicle body by a first sensor while the vehicle is moving; determining a predetermined information related to the vehicle and/or a second sensor; dynamically defining a blind spot area around the vehicle according to the turning angle information and the predetermined information; and receiving a sensing signal regarding an object around the vehicle from the second sensor to determine whether the object is located in the blind spot area.Type: GrantFiled: December 20, 2021Date of Patent: June 11, 2024Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chung-Lien Ho, Wei-Kuo Chen
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Patent number: 12007405Abstract: Provided is a novel material analysis technique using a chemical sensor. By reversing the conventional approach, a material to be measured is provided as a receptor of the chemical sensor, and a response signal of the chemical sensor obtained by supplying a known gas or the like to the chemical sensor is obtained. From the response signal, it is possible to identify and distinguish the receptor material, and to obtain its composition and the like. By analyzing the response signal by means of a statistical or machine learning technique such as principal component analysis, linear discriminant analysis, or a support vector machine, the above-mentioned identification and the like can be performed with high accuracy.Type: GrantFiled: June 4, 2019Date of Patent: June 11, 2024Assignee: NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Kosuke Minami, Genki Yoshikawa, Gaku Imamura, Kota Shiba
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Patent number: 12007259Abstract: A multi-dimensional spatial positioning system and method for disturbance source. The system includes a distributed-optical fiber sensor, a sensing optical fiber, a coordinate system, a disturbance source to be monitored, a first signal group, and a second signal group. The disturbance source is positioned by combining an array signal processing method with the distributed optical fiber sensor, using different laying manners for the sensing optical fiber and a certain number of flexibly selected sensing units distributed a certain distance from each other along a line, and combining with a special signal processing method, thereby realizing a function of being capable of monitoring multi-dimensional spatial position information of the disturbance source in real time in both short and long distances.Type: GrantFiled: December 30, 2019Date of Patent: June 11, 2024Assignee: SHANGHAI INSTITUTE OF OPTICS AND FINE MECHANICS, CHINESE ACADEMY OF SCIENCESInventors: Zhaoyong Wang, Jiajing Liang, Boqi Chen, Haiwen Cai, Qing Ye
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Patent number: 12010302Abstract: Disclosed according to one exemplary embodiment includes not limited to: a filtering unit configured to generate filtering information by filtering a residual image corresponding to a difference between an original image and a prediction image; an inverse filtering unit configured to generate inverse filtering information by inversely filtering the filtering information; an estimator configured to generate the prediction image based on the original image and reconstruction information; a CNN-based in-loop filter configured to receive the inverse filtering information and the prediction image and to output the reconstruction information; and an encoder configured to perform encoding based on the filtering information and information of the prediction image, and wherein the CNN-based in-loop filter is trained for each of the plurality of artefact sections according to an artefact value or for each of the plurality of quantization parameter sections according to a quantization parameter.Type: GrantFiled: December 26, 2022Date of Patent: June 11, 2024Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventor: Mun Churl Kim
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Patent number: 12004558Abstract: A method of, and equipment for gathering fibres entrained a gas stream, for example by melt blowing, comprises an enclosure having an inlet, through which a gas stream carrying entrained fibres may be directed into the enclosure, a fibre outlet from which an assembly of gathered fibres may be withdrawn from the enclosure and an exhaust outlet through which gas may pass out of the enclosure. The enclosure is constructed to provide a pathway for the fibres from the inlet to the fibre outlet in which surplus gas in the gas stream is separated from the entrained fibres and directed to the exhaust outlet, thereby reducing turbulence in the fibres in the enclosure which may affect the quality of the finished assembly.Type: GrantFiled: February 1, 2022Date of Patent: June 11, 2024Assignees: BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED, TOBACCO RESEARCH AND DEVELOPMENT INSTITUTE (PROPRIETARY) LIMITEDInventors: Gary Fallon, John Richardson, Ian King, Gerhard Malin Le Roux, Arnold Leslie Herholdt
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Patent number: 12005427Abstract: A catalyst for methanation reaction and a method for preparing methane are provided. The catalyst for methanation reaction includes a core, a shell encapsulating the core, and an active metal. The core includes cerium dioxide (CeO2), the shell includes zirconium dioxide (ZrO2), and the active metal is in particle form and is disposed on an outer surface of the shell layer.Type: GrantFiled: September 16, 2022Date of Patent: June 11, 2024Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Yen-Chih Chen, Man-Yin Lo, Hsi-Yen Hsu, Ying-Chieh Lee, Yuan-Peng Du
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Patent number: 12009516Abstract: A fast charging lithium-ion battery includes a positive electrode plate, a negative electrode plate, a separator, and an electrolyte. The positive electrode plate includes a positive current collector and a positive active material layers. The negative electrode plate includes a negative current collector and negative active material layers. The negative active material layers include titanium niobium oxide, lithium titanate, or a combination thereof. The separator is disposed between the positive electrode plate and the negative electrode plate. The electrolyte contacts the positive electrode plate and the negative electrode plate. The negative active material layers have an effective area corresponding to the positive electrode plate. The negative active material layers have a thickness on one surface of the negative current collector. A ratio of the effective area to the thickness is greater than 2×105 mm.Type: GrantFiled: September 18, 2020Date of Patent: June 11, 2024Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Deng-Tswen Shieh, Sheng-Fa Yeh, Shih-Chieh Liao, Ching-Yu Chen, Hao-Tzu Huang
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Patent number: 12004971Abstract: A cam system for an assistive device and related methods are disclosed. The cam system may comprise a multi (e.g., dual) cam profile and a cam follower.Type: GrantFiled: May 22, 2019Date of Patent: June 11, 2024Assignees: The Regents of the University of Michigan, REHABILITATION INSTITUTE OF CHICAGO, Northwestern UniversityInventors: Elliott J. Rouse, Maxwell Shepherd, Hashim Quraishi, Leo Mcmanus
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Patent number: 12006460Abstract: A photoelectric conversion compound is provided. The photoelectric conversion compound has a structure represented by formula (I): wherein D represents an inorganic luminescent group; each of R1, R2, and R3 independently represents a hydrogen atom or a C1-6 alkyl group; R4 represents a single bond or a C1-6 alkylene group; m represents an integer of 1-10; k represents an integer of 1-1,000; and n represents an integer of 1-10,000.Type: GrantFiled: December 30, 2021Date of Patent: June 11, 2024Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Min-Tsung Kuan, Wen-Hsien Wang, Yi-Chang Du, Szu-Lin Wang, Wen-Hsien Chou, Hsin-Hsin Hsieh