Patents Assigned to INSTITUTE
  • Publication number: 20180028962
    Abstract: The present invention generally relates to methods and systems for capturing a Lewis acid gas (e.g., CO2). In some embodiments, the methods and systems utilize an ionic liquid incorporated into one or more electrochemical cells.
    Type: Application
    Filed: July 26, 2017
    Publication date: February 1, 2018
    Applicant: Massachusetts Institute of Technology
    Inventors: Trevor Alan Hatton, Paul Brown, Sahag Voskian
  • Publication number: 20180034065
    Abstract: An electrocatalyst is provided. The electrocatalyst includes Pd-containing metal nitride, wherein the metal is Co, Fe, Y, Lu, Sc, Ti, V, Cu, Ni, or a combination thereof. The molar ratio between the metal and Pd is greater than 0 and less than or equal to 0.8. A fuel cell utilizing the above electrocatalyst is further provided.
    Type: Application
    Filed: December 22, 2016
    Publication date: February 1, 2018
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Wen-Hsuan CHAO, Chiung-Hui HUANG, Ping-Hsing YANG, Shan-Haw CHIOU, Keng-Yang CHEN, Chien-Ming LAI, Li-Duan TSAI
  • Publication number: 20180031042
    Abstract: Snap-in bushings are disclosed that enable sealing of sample chambers in MAS-NMR rotors for high pressure and/or high temperature operation that enhance pressure limits up to about 400 bar and temperature limits up to at least about 250° C.
    Type: Application
    Filed: August 1, 2016
    Publication date: February 1, 2018
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Eric D. Walter, Jesse A. Sears, JR., Hardeep S. Mehta, David W. Hoyt
  • Publication number: 20180028081
    Abstract: In an automated methodology for in vivo image-guided cell patch clamping, a cell patch clamping device is moved into position and targeted to a specific cell using automated image-guided techniques. Cell contact is determined by analyzing the temporal series of measured resistance levels at the clamping device as it is moved. The difference between successive resistance levels is compared to a threshold, which must be exceeded before cell contact is assumed. Pneumatic control methods are used to achieve gigaseal formation and cell break-in, leading to whole-cell patch clamp formation. An automated robotic system capable of performing this methodology automatically performs patch clamping in vivo, automatically locating cells through image guidance and by analyzing the temporal sequence of electrode impedance changes.
    Type: Application
    Filed: July 6, 2017
    Publication date: February 1, 2018
    Applicants: Massachusetts Institute of Technology, Georgia Tech Research Corporation
    Inventors: Ho-Jun Suk, Edward S. Boyden, Ingrid van Welie, Brian Douglas Allen, Suhasa B. Kodandaramaiah, Craig R. Forest
  • Publication number: 20180030187
    Abstract: A polymer, ion exchange membrane, and structural enhanced membrane employing the same are provided. The polymer includes a first repeating unit and a second repeating unit. In particular, the first repeating unit is and, the second repeating unit is wherein R+ can be A? can be F?, Cl?, Br?, I?, OH?, HCO3?, HSO4?, SbF6?, BF4?, H2PO4?, H2PO3?, or H2PO2?; Y1 and Y2 can be independently —O—, —S—, —CH2—, or —NH—; Ra and Rb can be independently hydrogen or C1-8 alkyl group; i, j, and k can be independently 0 or an integer from 1 to 6; R1 can be C1-10 alkyl group or C5-6 cycloalkyl group; and, R2 and R3 can be independently hydrogen, C1-8 alkyl group, vinyl group, C6-12 aryl group, or allyl group.
    Type: Application
    Filed: May 4, 2017
    Publication date: February 1, 2018
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chiu-Tung WANG, Li-Duan TSAI, Cheng-Hsiu TSAI, Hsuan-Wei LEE, Chiu-Hun SU, Ming-Chou CHEN
  • Publication number: 20180030889
    Abstract: According to one embodiment, a drive device includes a first piston reciprocatively along a first direction within a first mount plane, a first crankshaft orthogonal to the first mount plane, a first XY separation crank mechanism between the first piston and the first crankshaft, which converts reciprocating motion of the first piston and rotary motion of the first crankshaft into each other, a second piston reciprocatively along a second direction symmetrical to the first direction within a second mount plane symmetrical to the first mount plane about a central reference plane, a second crankshaft orthogonal to the second mount plane, a second XY separation crank mechanism between the second piston and the second crankshaft, which converts reciprocating motion of the second piston and rotary motion of the second crankshaft into each other, and a coupler-synchronizing mechanism which rotates the first and second crankshafts in synchronous with each other.
    Type: Application
    Filed: August 31, 2017
    Publication date: February 1, 2018
    Applicant: Z Mechanism Technology Institute Co., Ltd.
    Inventors: Yasuo Yoshizawa, Takumi Yoshizawa, Yutaka Yoshizawa, Satoshi Yoshizawa, Shuji Ogai
  • Publication number: 20180030049
    Abstract: Disclosed is a preparation method for praziquantel and intermediates thereof. The method includes: obtaining a target product praziquantel by using ?-phenethylamine as an initial raw material through a condensation reaction with chloroacetyl chloride, a substitution reaction with ethanolamine, and an acylation reaction with cyclohexanecarbonyl chloride, followed by an oxidation reaction and cyclization reaction. Also disclosed are two key intermediates, namely, a compound of formula IV and a compound of formula V for preparing praziquantel. The preparation method is reasonable and simple in its technological design, uses moderate reaction conditions, and is economical and environmentally friendly. Additionally, the raw materials are inexpensive and easy to obtain, the key intermediates are easy to prepare, and the total reaction yield and purity of the obtained target compound praziquantel is high, so that industrialized mass production is easy to achieve.
    Type: Application
    Filed: February 12, 2015
    Publication date: February 1, 2018
    Applicants: Zhejiang Hisun Pharmaceutical Co., Ltd., Shanghai Institute of Pharmaceutical Industry
    Inventors: Fuli ZHANG, Zhezhou YANG, Rusheng BAO, Weiwei XU, Hua BAI
  • Publication number: 20180034090
    Abstract: Redox flow devices are described in which at least one of the positive electrode or negative electrode-active materials is a semi-solid or is a condensed ion-storing electroactive material, and in which at least one of the electrode-active materials is transported to and from an assembly at which the electrochemical reaction occurs, producing electrical energy. The electronic conductivity of the semi-solid is increased by the addition of conductive particles to suspensions and/or via the surface modification of the solid in semi-solids (e.g., by coating the solid with a more electron conductive coating material to increase the power of the device). High energy density and high power redox flow devices are disclosed. The redox flow devices described herein can also include one or more inventive design features. In addition, inventive chemistries for use in redox flow devices are also described.
    Type: Application
    Filed: June 8, 2017
    Publication date: February 1, 2018
    Applicants: Massachusetts Institute of Technology, 24-M Technologies, Inc.
    Inventors: Yet-Ming Chiang, W. Craig Carter, Bryan Y. Ho, Mihai Duduta, Pimpa Limthongkul
  • Publication number: 20180035550
    Abstract: An apparatus for assembling devices, comprising a plurality of actuated devices disposed on a substrate, each of the actuated devices comprising a first electrode disposed on and electrically connect to the substrate, a connecting pad disposed on the substrate, an electro-active polymer layer comprising a first surface disposed on the connecting pad and a second surface, and a second electrode disposed on the second surface of the electro-active polymer layer and electrically connected to the substrate.
    Type: Application
    Filed: July 29, 2016
    Publication date: February 1, 2018
    Applicant: Industrial Technology Research Institute
    Inventors: Chin-Hung Wang, Yu-Wei Huang
  • Publication number: 20180027781
    Abstract: L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates for treatment, amelioration and/or prevention of protein aggregation/tangles/plaques and diseases associated with protein aggregation/tangles/plaques. In particular, treatments and uses for L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates include Alzheimer's disease (AD), Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Huntington disease (HD).
    Type: Application
    Filed: October 6, 2017
    Publication date: February 1, 2018
    Applicant: THE INSTITUTE FOR ETHNOMEDICINE
    Inventors: Kenneth Rodgers, Rachael Dunlop, Paul A. Cox
  • Publication number: 20180035230
    Abstract: Provided are an encoding method of a multichannel signal, an encoding apparatus to perform the encoding method, a multichannel signal processing method, and a decoding apparatus to perform the decoding method. The decoding method may include identifying an N/2-channel downmix signal derived from an N-channel input signal; and generating an N-channel output signal from the identified N/2-channel downmix signal using a plurality of one-to-two (OTT) boxes. If a low frequency effect (LFE) channel is absent in the output signal, the number of OTT boxes may be equal to N/2 where N/2 denotes the number of channels of the downmix signal.
    Type: Application
    Filed: February 17, 2016
    Publication date: February 1, 2018
    Applicant: Electronics and Telecommunications Research Institute
    Inventors: Seung Kwon BEACK, Jeong Il SEO, Jong Mo SUNG, Tae Jin LEE, Dae Young JANG, Jin Soo CHOI
  • Publication number: 20180030085
    Abstract: The present invention relates to the field of pharmaceutical chemistry, and particularly to a crystal form of Abiraterone propionate and a preparation method therefor. Characteristic diffraction peaks occur at positions, where the 2? value is 5.7°, 11.9°, 12.4°, 14.9°, 15.8°, 16.7°, 18.5°, 19.1°, 21.7°, 22.4°, and 39.9°±0.2°, in an X-ray powder diffraction spectrum of the crystal form of Abiraterone propionate.
    Type: Application
    Filed: February 3, 2016
    Publication date: February 1, 2018
    Applicant: CHONGQING PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD
    Inventors: Naiguo XING, Yan SHANGGUAN, Deping ZHENG, Fanglu CHEN
  • Publication number: 20180034524
    Abstract: The disclosure is directed to a method and apparatuses for controlling configurable split bearer based on UE assisted feedback. In one aspect, the method would include not limited to: receiving a first configuration message comprising an enable indicator which indicates that a first feedback signaling is to be transmitted in response to any one of a plurality of triggering events comprising a first triggering event and a second triggering event; evaluating, based on a first evaluation of any one of the plurality of triggering events, a wireless connection to a first wireless network having determined to be temporarily unavailable which corresponds to the first trigger event that triggers the first feedback signaling; transmitting, after receiving the enable indicator, the first feedback signaling comprising a first cause which indicates the first triggering event of the plurality of triggering events; and maintaining an aggregation configuration.
    Type: Application
    Filed: July 26, 2017
    Publication date: February 1, 2018
    Applicant: Industrial Technology Research Institute
    Inventors: Wei-Chen Pao, Tzu-Jane Tsai
  • Publication number: 20180034029
    Abstract: A composite separator is disclosed. The composite separator includes a base membrane, and a composite gel composited with the base membrane. The composite gel includes a gel polymer and a nano-barium sulfate dispersed in the gel polymer. A surface of the nano-barium sulfate is modified with lithium carboxylate group. A method for preparing the composite separator and a lithium-ion battery are also provided.
    Type: Application
    Filed: October 6, 2017
    Publication date: February 1, 2018
    Applicants: Jiangsu Huadong Institute of Li-Ion Battery Co., Ltd., Tsinghua University
    Inventors: YU-MING SHANG, XIAO-LEI DING, XIANG-MING HE, LI WANG, JIAN-JUN LI, YAO-WU WANG, JIAN GAO
  • Publication number: 20180035438
    Abstract: The disclosure is directed to a method and apparatuses for controlling quality of experience (QoE) based on UE assisted feedback. In one aspect, the method would include not limited to: receiving an enable indicator which indicates a first feedback signaling to be transmitted; performing a quality of experience (QoE) evaluation for fulfilling a performance requirement; and transmitting the first feedback signaling including a first preferred configuration of licensed wireless connection in response to performing the QoE evaluation, wherein the wireless connection comprises a licensed wireless connection and a licensed-assisted access connection.
    Type: Application
    Filed: July 26, 2017
    Publication date: February 1, 2018
    Applicant: Industrial Technology Research Institute
    Inventors: Wei-Chen Pao, Tzu-Jane Tsai
  • Publication number: 20180033879
    Abstract: A method for manufacturing a semiconductor device includes sequentially stacking a first epitaxial layer, a sacrificial layer, a second epitaxial layer, and a third epitaxial layer on a first substrate, forming a trench which penetrates the third epitaxial layer, the second epitaxial layer, and the sacrificial layer, forming a structure layer on an upper surface of the third epitaxial layer, forming a metal film which covers an inner surface of the trench and the structure layer, forming a second substrate which fills the trench and covers the metal film, and separating the second epitaxial layer, the third epitaxial layer, and the structure layer from the first epitaxial layer.
    Type: Application
    Filed: May 10, 2017
    Publication date: February 1, 2018
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Sung-Bum BAE, Sung Bock KIM
  • Publication number: 20180033772
    Abstract: A semiconductor device is provided. The semiconductor device includes at least one first die, a rib structure enclosing the at least one first die, and a molding layer covering the at least one first die. The rib structure is formed of a first material and the molding layer is formed of a second material. A Young's modulus of the first material is larger than a Young's modulus of the second material. The rib structure includes a through hole, and the through hole is filled with a conductive material.
    Type: Application
    Filed: October 11, 2017
    Publication date: February 1, 2018
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chih-Ming SHEN, Shih-Hsien WU, Ming-Ji DAI
  • Publication number: 20180030054
    Abstract: Provided in the present invention is a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. Also provided in the present invention are a pharmaceutical composition comprising a compound of formula (I) and a use and method for preventing or treating cell proliferative conditions and/or FLT3-related conditions, in particular for conditions responding to the inhibition of FLT3 kinase (especially FLT3/ITD mutant kinases).
    Type: Application
    Filed: August 7, 2015
    Publication date: February 1, 2018
    Applicants: HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES, HEFEI COSOURCE PHARMACEUTICAL CO., LTD.
    Inventors: Jing LIU, Qingsong LIU, Xixiang LI, Aoli WANG, Hong WU, Cheng CHEN, Wenchao WANG, Chen HU, Zheng ZHAO, Jiaxin WU, Juan LIU, Kailin YU, Wei WANG, Li WANG, Beilei WANG
  • Publication number: 20180029988
    Abstract: Disclosed are novel compounds of specific chemical structures having inhibitory activity on c-Myc/Max/DNA complex formation or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: July 28, 2017
    Publication date: February 1, 2018
    Applicants: NATIONAL CANCER CENTER, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Kyung Chae JEONG, Hwan Jung LIM, Seong Jun PARK, Ho Kyung SEO, Kyung Ohk AHN, Sang Jin LEE, Eun Sook LEE
  • Publication number: 20180029949
    Abstract: A controlled-release solid nitride fertilizer from fly ash and a method for making are described. The fertilizer includes a nitrogen source including at least one solid nitride combined with at least one precipitation-inhibiting agent and with at least one moisture-retention agent, all compressed together to form a porous release structure that in contact with water releases ammonium ions as a nitrogen nutrient at a substantially uniform release rate over a selected release period and thereby maximizes nitrogen-use efficiency by plants.
    Type: Application
    Filed: July 28, 2016
    Publication date: February 1, 2018
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: James E. Amonette, Josef Matyas