Patents Assigned to INSTITUTE
  • Patent number: 9764378
    Abstract: In exemplary implementations of this invention, an actuated fabricator deposits structural elements (e.g., tensile structural elements) in a 3D pattern over large displacements. The fabricator is supported by at least three elongated support members. It includes onboard actuators that translate the fabricator relative to the ends of the support members. The fabricator is configured, by actuating different translations along different support members, to translate itself throughout a 3D volume. In some implementations, each of the actuators use fusible material to fuse metal tapes together, edge-to-edge, to form a hollow structure that can be shortened or lengthened.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: September 19, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Benjamin Peters, Neri Oxman
  • Patent number: 9768442
    Abstract: Provided are a carbon electrode particularly suitable to be used as a negative electrode of an energy storing apparatus and the like and a method for manufacturing the same by forming the carbon electrode by heat-treating a natural carbon material such as a natural fiber sheet including a natural fiber or cellulose sheet including a natural cellulose fiber which is a natural material other than a petroleum-based material or a petroleum-based synthetic material to reduce manufacturing cost, shorten a manufacturing process, minimize discharge of a hazardous substance, and uniformly maintain storage capacitance even in repeated charging and discharging when being applied to the energy storing apparatus. The carbon electrode includes any one of an alkaline metal particle and an alkaline earth metal particle having an average particle size of less than 100 nm which is formed on a surface in a process of carbonizing a natural carbon material.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: September 19, 2017
    Assignee: Korea Institute of Energy Research
    Inventors: Seong Ok Han, Hee Yeon Kim, In Sub Han, Se Young Kim, Young Hoon Seong, Doo Won Seo
  • Patent number: 9765313
    Abstract: The present invention relates to the field of genetic engineering, in particular, the present invention relates to a method for producing a phytase variant with an improved thermal stability, and a phytase variant and the use thereof. The phytase variant contains at least one proline modification, compared to the phytase from Escherichia coli and other mutants thereof. The phytase variants with the modification have preferably improved properties, such as the thermal stability, optimal reaction temperature, pH property, specific activity, protease resistance and performance in animal feeds.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: September 19, 2017
    Assignee: Feed Research Institute, Chinese Academy of Agricultural Sciences
    Inventors: Bin Yao, Huoqing Huang, Huiying Luo, Chao Shao, Yingguo Bai, Yaru Wang, Peilong Yang, Pengjun Shi, Kun Meng, Heng Zhao, Rui Ma
  • Patent number: 9764970
    Abstract: The disclosure provides an ozone contact tank, which includes a water inlet gallery (1), an aeration gallery (2), a water distribution zone (3), a reaction zone (4) and a water outlet trough (5) which are disposed according to the intake order and are communicated in sequence; the top of the water inlet gallery (1) is communicated with the top of the aeration gallery (2); the bottom of the aeration gallery (2) is communicated with a water inlet end of the water distribution zone (3) via a narrow passage (6); the top of the water distribution zone (3) is communicated with the bottom of the reaction zone (4) via a perforated plate (41); the top of the reaction zone (4) is communicated with the water outlet trough (5). The disclosure also provides an ozone contact method using the ozone contact tank, which can greatly improve the disinfection effect.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: September 19, 2017
    Assignee: HARBEN INSTITUTE OF TECHNOLOGY SHENZHEN GRADUATE SCHOOL
    Inventors: Ji Li, Wenyi Dong
  • Patent number: 9763984
    Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.
    Type: Grant
    Filed: December 21, 2013
    Date of Patent: September 19, 2017
    Assignee: Astellas Institute for Regenerative Medicine
    Inventors: Qiang Feng, Shi-Jiang Lu, Robert P. Lanza
  • Patent number: 9764045
    Abstract: An optimized coding sequence of human blood clotting factor eight (VIII) and a promoter may be used in vectors, such as rAAV, for introduction of factor VIII, and/or other blood clotting factors and transgenes. Exemplary of these factors and transgenes are alpha-1-antitrypsin, as well as those involved in the coagulation cascade, hepatocye biology, lysosomal storage, urea cycle disorders, and lipid storage diseases. Cells, vectors, proteins, and glycoproteins produced by cells transformed by the vectors and sequence, may be used in treatment.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: September 19, 2017
    Assignees: UCL BUSINESS PLC, THROMBOSIS RESEARCH INSTITUTE, ST. JUDE CHILDREN'S RESEARCH HOSPITAL
    Inventors: Amit Nathwani, Natalie Ward, Adrian Thrasher, Edward Tuddenham, John Mcvey, John Gray, Andrew Davidoff
  • Patent number: 9763606
    Abstract: A method including placing a portion of a foot of a newborn in a device, the device including a light emitter and a corresponding receiver coupled on opposite sides of the device, the device further including a processor for processing data from the light emitter and receiver; and determining a presence of congenital heart disease. An apparatus including a body including a chamber of a size to accommodate a portion of a newborn's foot; at least one light emitter and a corresponding detector coupled on opposite sides of the body, the emitter configured to emit light of a prescribed wavelength into the chamber; and a processor coupled to the body and configured to receive a signal from the at least one detector.
    Type: Grant
    Filed: August 23, 2011
    Date of Patent: September 19, 2017
    Assignee: LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER
    Inventors: Ruey-Kang Chang, Yann Ping Pan
  • Patent number: 9768873
    Abstract: An electro-optical oscillator includes, in part, a modulator, a signal splitter, N photodiodes with N being an integer greater than one, a signal combiner, and a filter. The modulator modulates an optical signal in accordance with a feedback signal. The splitter splits the modulated optical signal into N optical signals each delivered to a different one of N photo-diodes. Each of the N photo-diodes converts the optical signal it receives to a current signal. The signal combiner combines the N current signals received from the N photo-diodes to generate a combined current signal. The filter filters the combined current signal and generates the feedback signal. The electro-optical oscillator optionally includes, in part, N variable optical gain/attenuation components each amplifying/attenuating a different one of the N optical signals generated by the splitter.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: September 19, 2017
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Seyed Ali Hajimiri, Firooz Aflatouni, Behrooz Abiri
  • Patent number: 9766981
    Abstract: A context-awareness synchronization apparatus, method, and non-transitory computer readable storage medium are provided. The synchronization apparatus is electrically connected to a storage server via a network. The synchronization apparatus executes an operating system and an agent program installed on the operating system. The agent program configures a first and second individual spaces within the synchronization apparatus, determines a context of the synchronization apparatus, selects a first and second policy sets from a plurality of policy sets for the first and second individual spaces according to the context respectively, and handles the first and second individual spaces according to the first and second policy sets respectively. The first and second individual spaces are unaware of each other and only recognized by the agent program installed on the operating system.
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: September 19, 2017
    Assignee: Institute For Information Industry
    Inventors: Ko-Yang Wang, Yen-Hung Kuo, Yu-Lin Jeng
  • Patent number: 9766226
    Abstract: Compositions and methods for the measuring toxicity, antioxidant capacity, and oxidative stress are provided.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: September 19, 2017
    Assignee: Lankenau Institute for Medical Research
    Inventor: Iraimoudi S. Ayene
  • Patent number: 9765118
    Abstract: As explained hereinbefore, the C12orf59 gene of the present invention suppresses cancer cell invasion and inhibits cancer cell survivability, and the over expression of C12orf59 protein or a fragment thereof inhibits cancer cell invasion, so that C12orf59 gene or a fragment thereof not only can be effectively used for the pharmaceutical composition for preventing and treating cancer but also can be used as a clinical marker for screening a cancer treatment agent candidate, for diagnosing various cancers or for predicting pathological stage. In addition, the C12orf59 gene or a fragment thereof of the present invention can be used for the method for preventing and treating cancer and for the preparation of a pharmaceutical composition for preventing and treating cancer.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: September 19, 2017
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Semi Kim, Yunhee Lee
  • Patent number: 9766190
    Abstract: A method, system and apparatus are provided to measure magnetic characteristics of a comparatively thick magnetic sample in a magnetic field or nonmagnetic field by X-ray magnetic circular dichroism (XMCD). In particular, the method, system and apparatus measure the magnetic characteristics of the thick magnetic sample by irradiating the sample with X-ray, and detecting transmissive X-ray passing through the sample.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: September 19, 2017
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION HIGH ENERGY ACCELERATOR RESEARCH ORGANIZATION
    Inventors: Masao Yano, Kanta Ono
  • Patent number: 9765414
    Abstract: The present invention provides a heat treatment method of turnout track comprising performing an accelerated cooling on the turnout track to be treated having a railhead tread with a temperature of 650-900° C. so as to obtain the turnout track with full pearlite metallographic structure, wherein the accelerated cooling velocity performed on the working side of railhead of the turnout track is higher than that performed on the non-working side of the railhead of the turnout track. The present invention provides a turnout track obtained with a heat treatment process as depicted therein. The turnout track in present invention has good straightness; both the hardness and tensile strength of the working side of railhead are higher than that of the non-working side of railhead.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: September 19, 2017
    Assignees: PANGANG GROUP PANZHIHUA IRON & STEEL RESEARCH INSTITUTE CO., LTD., PANGANG GROUP PANZHIHUA STEEL & VANADIUM CO., LTD.
    Inventors: Ming Zou, Zhenyu Han, Dongsheng Mei, Yong Deng, Hua Guo, Quan Xu, Chunjian Wang
  • Patent number: 9767226
    Abstract: According to some aspects, a method of designing an object based on a three-dimensional model representing a shape of the object is provided. The object may be fabricated from a plurality of materials having one or more known physical properties, wherein the object is designed to exhibit one or more target properties. The method may comprise determining a first composition of the object by providing the three-dimensional model as input to a reducer tree, determining one or more physical properties of the object with the first composition by simulating the object with the first composition, comparing the determined one or more physical properties with the one or more target properties, and determining a second composition of the object based on a result of comparing the determined one or more physical properties with the one or more target properties.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: September 19, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Desai Chen, Pitchaya Sitthi-Amorn, David I. W. Levin, Piotr Didyk, Wojciech Matusik
  • Patent number: 9765129
    Abstract: The present invention relates generally to a method of increasing lipid oxidation in a mammal and to agents useful for same. More particularly, the present invention relates to a method of increasing lipid oxidation in a mammal by administering a ligand which interacts with the IL-6 receptor and signals via interaction with a gp130/LIF receptor heterodimer. In a related aspect, the present invention provides a method of increasing insulin sensitivity in a mammal. The method of present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterized by unwanted lipid accumulation (such as obesity, obesity induced-metabolic disorders, type II diabetes, dyslipidemia, glucose intolerance, insulin resistance, obstructive sleep apnea, cardiovascular disease or non-alcoholic fatty liver disease) or inadequate insulin sensitivity.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: September 19, 2017
    Assignees: Baker Medical Research Institute, Christian-Albrechts-Universität zu Kiel
    Inventors: Mark Anthony Febbraio, Stefan Rose-John
  • Patent number: 9768785
    Abstract: Digital focal plane arrays (DFPAs) with multiple counters per unit cell can be used to convert analog signals to digital data and to filter the digital data. Exemplary DFPAs include two-dimensional arrays of unit cells, where each unit cell is coupled to a corresponding photodetector in a photodetector array. Each unit cell converts photocurrent from its photodetector to a digital pulse train that is coupled to multiple counters in the unit cell. Each counter in each unit cell can be independently controlled to filter the pulse train by counting up or down and/or by transferring data as desired. For example, a unit cell may perform in-phase/quadrature filtering of homodyne- or heterodyne-detected photocurrent with two counters: a first counter toggled between increment and decrement modes with an in-phase signal and a second counter toggled between increment and decrement modes with a quadrature signal.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: September 19, 2017
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Kenneth I. Schultz, Brian Tyrrell, Michael W. Kelly, Curtis B. Colonero, Lawrence M. Candell, Daniel Mooney
  • Patent number: 9768197
    Abstract: A flexible display panel includes a bending area and a surrounding area adjacent to the bending area. The barrier layer includes first silicon nitride layers and first silicon oxide layers which are overlapped with the bending area. The first silicon nitride layers and the first silicon oxide layers are stacked alternately. Each of the first silicon nitride layers may have a thickness less than or equal to about 400 ?, and each of the first silicon oxide layers may have a thickness less than or equal to about 650 ?.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: September 19, 2017
    Assignees: Samsung Display Co., Ltd., Korea Advanced Institute of Science and Technology
    Inventors: Jun Namkung, Seung Min Jane Han, Youbin Kim
  • Patent number: 9769676
    Abstract: A method of handling a beamforming feedback for a base station of the wireless communication system comprises receiving a message comprising information of an interference caused by a communication between the base station and a communication device of the wireless communication system; determining an accuracy level of channel information according to the information of the interference; controlling the communication device to transmit the channel information with the accuracy level to the base station; and performing a beamforming according to the channel information to communicate with the communication device, after receiving the channel information transmitted by the communication device.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: September 19, 2017
    Assignee: Industrial Technology Research Institute
    Inventor: Ping-Heng Kuo
  • Patent number: 9767368
    Abstract: A method and a system computationally performs scene analysis of semantic traffic spaces based on an adaptive spatio-temporal ray-based approach. The method includes acquiring a spatial semantic environment map including semantic context data, calculating at least one feature for at least one location on the spatial environment map taking into account the semantic context of the location and determining a category for the at least one location based on the at least one calculated feature. A feature is a ray based feature calculated by integrating input values along at least one ray extending in least one of a space dimension and a time dimension. The ray may have a ray shape corresponding to a general shape of a road and/or the at least one spatially extending ray follows a course of the road and/or is perpendicular to a surrounding road segment orientation.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: September 19, 2017
    Assignee: HONDA RESEARCH INSTITUTE EUROPE GMBH
    Inventors: Jannik Fritsch, Thomas Weisswange
  • Patent number: 9767251
    Abstract: Disclosed herein are methods of determining the sequence and/or positions of modified bases in a nucleic acid sample present in a circular molecule with a nucleic acid insert of known sequence comprising obtaining sequence data of at least two insert-sample units. In some embodiments, the methods comprise obtaining sequence data using circular pair-locked molecules. In some embodiments, the methods comprise calculating scores of sequences of the nucleic acid inserts by comparing the sequences to the known sequence of the nucleic acid insert, and accepting or rejecting repeats of the sequence of the nucleic acid sample according to the scores of one or both of the sequences of the inserts immediately upstream or downstream of the repeats of the sequence of the nucleic acid sample.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: September 19, 2017
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chao-Chi Pan, Jenn-Yeh Fann, Chung-Fan Chiou, Hung-Chi Chien, Hui-Ling Chen