Abstract: Disclosed is a solar cell including a first electrode, a second electrode, and a first conversion layer disposed therebetween. The first electrode is closer to a light incident side than the second electrode. The first conversion layer is a composition-gradient perovskite. A part of the first conversion layer adjacent to the first electrode has an energy gap less than that of a part of the first conversion layer adjacent to the second electrode.

Abstract: An optimized coding sequence of human blood clotting factor eight (VIII) and a promoter may be used in vectors, such as rAAV, for introduction of factor VIII, and/or other blood clotting factors and transgenes. Exemplary of these factors and transgenes are alpha-1-antitrypsin, as well as those involved in the coagulation cascade, hepatocye biology, lysosomal storage, urea cycle disorders, and lipid storage diseases. Cells, vectors, proteins, and glycoproteins produced by cells transformed by the vectors and sequence, may be used in treatment.

Abstract: The invention is directed to methods of inducing apoptosis, arresting cell cycle, or inhibiting cellular proliferation, or any combination thereof, in a tumor cell, by administration of an effective amount of an N-acyl homoserine lactone analog (AHL), optionally in conjunction with a tumor modulating agent such tumor necrosis factor (TNF) related apoptosis inducing ligand (TRAIL) to the patient. Novel bioactive analogs of an N-acyl homoserine lactone are also provided.

Abstract: The invention relates to methods of treatment and diagnosis of subjects with cancer. In some aspects, the invention relates to methods of treatment and diagnosis of subjects with cancer, wherein the cancer is characterized by a Notch pathway activation mutation or by resistance to a Notch pathway inhibitor.

Abstract: Provided are a method of analyzing ubiquitin-proteasome activity with respect to a target polypeptide and a method of screening a ubiquitin-proteasome inhibitor. According to the provided methods, the pattern of lysis of a target polypeptide by a ubiquitin-proteasome in target cells may be quantitatively analyzed in a rapid and highly sensitive way, a ubiquitin-proteasome inhibitor may be screened in a rapid and highly sensitive way, and an anticancer agent and the activity thereof may be rapidly screened.

Abstract: The disclosure provides an ozone contact tank, which includes a water inlet gallery (1), an aeration gallery (2), a water distribution zone (3), a reaction zone (4) and a water outlet trough (5) which are disposed according to the intake order and are communicated in sequence; the top of the water inlet gallery (1) is communicated with the top of the aeration gallery (2); the bottom of the aeration gallery (2) is communicated with a water inlet end of the water distribution zone (3) via a narrow passage (6); the top of the water distribution zone (3) is communicated with the bottom of the reaction zone (4) via a perforated plate (41); the top of the reaction zone (4) is communicated with the water outlet trough (5). The disclosure also provides an ozone contact method using the ozone contact tank, which can greatly improve the disinfection effect.

Abstract: A device for use in the repair of an ear drum in a subject in need of such treatment, said device: having a tensile strength Youngs Modulus between approximately 12.5 and 40 MPa; comprising one or more membrane layers, wherein at least one membrane layer comprises a plurality of pores; and wherein the device can support proliferation, migration and/or adhesion of cells selected from the group comprising at least any one or more of: keratinocytes, fibroblasts, vascular cells, mucosal epithelial cells, and stem cells.

Abstract: This disclosure relates to the field of Optical Coherence Tomography (OCT). This disclosure particularly relates to an OCT system with improved motion contrast. This disclosure particularly relates to motion contrast methods for such OCT systems. The OCT system of this disclosure may have a configuration that scans a physical object, which has a surface and a depth, with a beam of light that has a beam width and a direction; acquires OCT signals from the scan; forms at least one A-scan using the acquired OCT signals; forms at least one B-scan cluster set using the acquired OCT signals that includes at least two B-scan clusters that each include at least two B-scans. The B-scans within each B-scan cluster set are parallel to one another and parallel to the direction of the beam of light. The OCT system may have a configuration that calculates OCT motion contrast using the at least one B-scan cluster set. This OCT system may form and display an image of the physical object.

Abstract: Provided herein is a multi-channel optical module including a plurality of laser diodes emitting light with different wavelengths, a thermoelectric cooling device including the plurality of laser diodes, a TO-can including the thermoelectric cooling device, and a holder combined with the TO-can and including a plurality of optical lenses focusing the light with different wavelengths and a multiplexer gathering focused light into a single optical fiber, wherein the holder has a shape in which the TO-can is cut along an axis of a path of the light with different wavelengths for active alignment of the plurality of optical lenses.

Abstract: The present invention provides a heat treatment method of turnout track comprising performing an accelerated cooling on the turnout track to be treated having a railhead tread with a temperature of 650-900° C. so as to obtain the turnout track with full pearlite metallographic structure, wherein the accelerated cooling velocity performed on the working side of railhead of the turnout track is higher than that performed on the non-working side of the railhead of the turnout track. The present invention provides a turnout track obtained with a heat treatment process as depicted therein. The turnout track in present invention has good straightness; both the hardness and tensile strength of the working side of railhead are higher than that of the non-working side of railhead.

Abstract: The present invention provides a method for labeling or detecting a protein with certain glycosyl groups. The methods are particularly useful for detecting cancer cells comprising the detected glycosyl groups. The present invention further provides labeling agents and detection agents, labeled proteins and mixtures, and kits and arrays thereof.

Abstract: An atomic clock including an ion trap assembly, a C-field coil positioned for generating a first magnetic field in the interrogation region of the ion trap assembly, a compensation coil positioned for generating a second magnetic field in the interrogation region, wherein the combination of the first and second magnetic fields produces an ion number-dependent second order Zeeman shift (Zeeman shift) in the resonance frequency that is opposite in sign to an ion number-dependent second order Doppler shift (Doppler shift) in the resonance frequency, the C-field coil has a radius selected using data indicating how changes in the radius affect an ion-number-dependent shift in the resonance frequency, such that a difference in magnitude between the Doppler shift and the Zeeman shift is controlled or reduced, and the resonance frequency, including the adjustment by the Zeeman shift, is used to obtain the frequency standard.

Abstract: A method of handling a beamforming feedback for a base station of the wireless communication system comprises receiving a message comprising information of an interference caused by a communication between the base station and a communication device of the wireless communication system; determining an accuracy level of channel information according to the information of the interference; controlling the communication device to transmit the channel information with the accuracy level to the base station; and performing a beamforming according to the channel information to communicate with the communication device, after receiving the channel information transmitted by the communication device.

Abstract: A leak hydrogen absorbing device is provided and includes an absorbing tank, having a gas inlet and a gas outlet; a spacer, disposed inside the absorbing tank, and partitioning an interior of the absorbing tank into multiple spaces; a hydrogen absorbing material, disposed in the spaces; a connecting tube, disposed on the spacer, and connecting the spaces; a pump, pumping a hydrogen-containing gas leaked in a closed environment to the absorbing tank through the gas inlet to be flowed through the spaces inside the absorbing tank, so that the hydrogen gas contained in the hydrogen-containing gas is absorbed by the hydrogen absorbing material; and a depressurizing portion, disposed at a terminal end of the absorbing tank, and storing a hydrogen-free gas passed through the hydrogen absorbing material. The hydrogen-free gas is discharged through the gas outlet when reaching a predetermined pressure.

Abstract: A method including placing a portion of a foot of a newborn in a device, the device including a light emitter and a corresponding receiver coupled on opposite sides of the device, the device further including a processor for processing data from the light emitter and receiver; and determining a presence of congenital heart disease. An apparatus including a body including a chamber of a size to accommodate a portion of a newborn's foot; at least one light emitter and a corresponding detector coupled on opposite sides of the body, the emitter configured to emit light of a prescribed wavelength into the chamber; and a processor coupled to the body and configured to receive a signal from the at least one detector.

Abstract: Disclosed herein are methods of determining the sequence and/or positions of modified bases in a nucleic acid sample present in a circular molecule with a nucleic acid insert of known sequence comprising obtaining sequence data of at least two insert-sample units. In some embodiments, the methods comprise obtaining sequence data using circular pair-locked molecules. In some embodiments, the methods comprise calculating scores of sequences of the nucleic acid inserts by comparing the sequences to the known sequence of the nucleic acid insert, and accepting or rejecting repeats of the sequence of the nucleic acid sample according to the scores of one or both of the sequences of the inserts immediately upstream or downstream of the repeats of the sequence of the nucleic acid sample.

Abstract: According to some aspects, a method of designing an object based on a three-dimensional model representing a shape of the object is provided. The object may be fabricated from a plurality of materials having one or more known physical properties, wherein the object is designed to exhibit one or more target properties. The method may comprise determining a first composition of the object by providing the three-dimensional model as input to a reducer tree, determining one or more physical properties of the object with the first composition by simulating the object with the first composition, comparing the determined one or more physical properties with the one or more target properties, and determining a second composition of the object based on a result of comparing the determined one or more physical properties with the one or more target properties.

Abstract: A liquid concentration detecting device including a first substrate, a first temperature sensing element and a concentration sensor is provided. The first temperature sensing element and the concentration sensor are respectively disposed on opposite first surface and second surface of the first substrate. The concentration sensor includes a second substrate, a porous element, a heating element and a second temperature sensing element. The second substrate is disposed above the second surface. A portion of the liquid flows into the concentration sensor through the porous element, and the heating element heats the liquid in the concentration sensor. The second temperature sensing element measures the temperature variation of the liquid in the concentration sensor. The measured temperature and the temperature variation are compared to deduce a concentration of the liquid under detection.

Abstract: An optical wavelength and optical power measurement device is provided. The optical wavelength and optical power measurement device includes: an input unit in which an optical connector that emits communication light of an infrared ray wavelength region is connected; a filter unit that separates the communication light of an infrared ray wavelength region and light of a visible ray wavelength region; a sensing unit that communicates with a path of the communication light of an infrared ray wavelength region of the filter unit and in which a signal of the communication light of an infrared ray wavelength region is input; and an inspection unit that communicates with a path of the light of the visible ray wavelength region of the filter unit and that inspects a surface of the optical connector.

Abstract: Disclosed are an apparatus for detecting pipe wall thinning, which measures a natural frequency of a pipe and determines a level of the pipe wall thinning, and a method thereof. The apparatus for detecting the pipe wall thinning includes a hitting member 10 for hitting the pipe T, a vibration measurement sensor 20 which measures a vibration signal generated when the pipe T is hit with the hitting member 10, and a control part 30 which compares the natural frequency calculated from the vibration signal measured from the vibration measurement sensor 20 with a natural frequency generated from a normal pipe in which wall thinning does not occur, and determines the level of the wall thinning of the pipe T.