Abstract: The invention relates to materials and methods for producing equivalents of tissues of the ocular surface, especially conjunctival tissue equivalents. The method of the invention involves biopsy of an appropriate tissue, primary culture in a certain medium, proliferative culture in a second medium, and differentiative culture in a third medium. The tissue equivalents are typically grown upon a substrate, typically amniotic membrane, which provides ease of handling as one advantage.
Type:
Grant
Filed:
March 31, 2003
Date of Patent:
May 23, 2006
Assignee:
Singapore Eye Research Institute
Inventors:
Donald Tan, Leonard Ang, Roger Beuerman
Abstract: The in-band adjacent-channel digital audio broadcasting system includes a scrambling unit for scrambling a signal to be broadcasted, thereby generating a scrambled signal; an outer coding unit for performing a first encoding of the scrambled signal, thereby generating an outer encoded signal; an outer interleaving unit for performing a first interleaving of the outer encoded signal a byte by byte basis, thereby generating an outer interleaved signal; an inner coding unit for performing a second encoding the outer interleaved signal, thereby generating an inner encoded signal; an inner interleaving unit for performing a second interleaving of the inner encoded signal, thereby generating an inner interleaved signal; a modulating unit for modulating the inner interleaved signal, thereby generating an orthogonal frequency division multiplexing (OFDM) symbols; a guard interval inserting unit for inserting a guard interval between the OFDM symbols in order to eliminate an inter-symbol interference, thereby generati
Type:
Grant
Filed:
September 28, 2001
Date of Patent:
May 23, 2006
Assignee:
Electronics and Telecommunications Research Institute
Inventors:
Young-Ho Jeong, So-Ra Park, Geon Kim, Soo-In Lee
Abstract: The invention describes HLA class II binding peptides encoded by the MAGE-A3 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4+ T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of the MAGE-A3 gene.
Type:
Grant
Filed:
May 18, 2001
Date of Patent:
May 23, 2006
Assignee:
Ludwig Institute for Cancer Research
Inventors:
Yi Zhang, Pascal Chaux, Thierry Boon-Falleur, Pierre van der Bruggen
Abstract: A flat antenna architecture for use in radio frequency monitoring systems including a patch antenna configured for use on a conductive surface of an object to be monitored. The patch antenna includes a conductive patch formed on a first surface of a dielectric base and an opposing surface on the dielectric base configured for attachment to the reflective surface of an object. This provides a patch antenna of relatively thin makeup having a lower cost and lower overall thickness and corresponding lower weight.
Abstract: A Comma-Free Reed-Solomon decoding circuit based on systolic array architecture that applies to a cell search in a wideband code division multiple access system, and more particularly a decoding circuit that employs a systolic array in its circuit structure. The systolic array for the decoding circuit comprises an input pattern generator, a processing element array designed in the form of a systolic array and a boundary processing element array. Given the skewed-form output results required by the systolic array and generated by the input pattern generator, the processing element array makes a correlating comparison, and outputs the results of the correlating comparison to the boundary processing element, so as to acquire the decoding results required by the Comma-Free Reed-Solomon code. The results indicate the frame boundary and scrambling code groups of the cell search in a wideband code division multiple access system.
Type:
Grant
Filed:
April 12, 2002
Date of Patent:
May 23, 2006
Assignee:
Chung Shan Institute of Science and Technology
Abstract: A styrene resin composition is provided which has a high molecular weight enabling a molded product obtained therefrom to have satisfactory strength, has a high melt mass-flow rate, high melt tension, and hence excellent moldability, and is less apt to gel during production, and a process for producing such a styrene resin composition. The styrene resin composition comprises a linear polystyrene having a weight average molecular weight of 200,000 to 350,000 and a multibranched polystyrene having a weight average molecular weight of 1,000,000 to 10,000,000, has an average molecular weight of 250,000 to 700,000, and a melt mass-flow rate (MFR) and melt tension (MT) which satisfy the following formulas (1) and (2) respectively: MFR?45×exp(?0.1×Mw×10?4)??(1) MT?0.07Mw×10?4+1.8.
Type:
Grant
Filed:
January 30, 2003
Date of Patent:
May 23, 2006
Assignees:
Dainippon Ink and Chemicals, Inc., Kawamura Institute of Chemical Research
Inventors:
Hiroyuki Yamazaki, Tsuyoshi Morita, Ren-Hua Jin
Abstract: An assembly apparatus for an optical transceiver has a positioning device and an assembly device. The assembly device has a base, a transverse adjustment mechanism adjustably mounted on the base, a clamping mechanism mounted on the transverse adjustment mechanism for clamping a control circuit board, a height adjusting mechanism adjustably mounted on the transverse adjustment mechanism, a longitudinal adjustment mechanism adjustably mounted on the height adjusting mechanism and element holding mechanism adjustably mounted on the longitudinal adjustment mechanism for holding a optical element. Accordingly, an optical transceiver can be conveniently assembled and tested with the assembly apparatus.
Type:
Grant
Filed:
July 16, 2004
Date of Patent:
May 23, 2006
Assignee:
Industrial Technology Research Institute
Inventors:
Min-Sheng Kao, Cheng-Hung Tsai, Cheng-Da Shaw, Shun-Tien Lee
Abstract: A multilevel converter-based, intelligent, universal transformer includes back-to-back, interconnected, multi-level converters coupled to a switched inverter circuit via a high-frequency transformer. The input of the universal transformer can be coupled to a high-voltage distribution system and the output of the universal transformer can be coupled to low-voltage applications. The universal transformer is smaller in size than conventional copper-and-iron based transformers, yet provides enhanced power quality performance and increased functionality.
Type:
Grant
Filed:
November 25, 2003
Date of Patent:
May 23, 2006
Assignee:
Electric Power Research Institute, Inc.
Inventors:
Jih-Sheng Lai, Arshad Mansoor, Arindam Maitra, Frank Goodman
Abstract: In a process for producing a deicing/anti-icing fluid, a byproduct stream is obtained from a process that produces monoalkyl esters of long chain fatty acids. The stream includes water, glycerol, and an alkali-containing compound. The stream is converted to a deicing/anti-icing fluid by adding an acid to the stream to neutralize the alkali-containing compound to produce an alkali salt that functions as a supplemental freezing point depressant.
Type:
Grant
Filed:
November 3, 2004
Date of Patent:
May 23, 2006
Assignee:
Battelle Memorial Institute
Inventors:
Satya P. Chauhan, William D. Samuels, Sara F. Kuczek, H. Nicholas Conkle
Abstract: A battery energy balance circuit and a battery charging bypass circuit is disclosed for batteries being charged at the same time to be charged equally. When the terminal voltages of the batteries are different, a controllable power device switch in the circuit switches on and off at a high frequency in order to reduce the input current to the batteries with higher terminal voltages and to increase the input current to the batteries with lower terminal voltages, achieving the goal of equal charging. The disclosed energy balance circuit can avoid damages to the batteries as a result of overcharging. When the number of batteries increases, one can expand the system in a modularized way to prevent inconvenience of circuit designs.
Type:
Grant
Filed:
November 24, 2003
Date of Patent:
May 23, 2006
Assignee:
Industrial Technology Research Institute
Inventors:
Pao-Chuan Lin, Chun-Hsien Lee, Yi-Shuo Huang, Chung-Lin Lee
Abstract: This invention relates to quercetin derivative, its preparation, and a pharmaceutical combination, as well as their medical uses for the prevention or treatment of diseases related to 5HT1A receptor or neuron cell damages, including Alzeheimer's disease, drug or alcohol dependence, sleep disorders or panic state; and for delaying senility, improving learning and memory, preventing and treatment of neuron cell damages caused by various kinds of cerebral damages.
Type:
Grant
Filed:
September 26, 2003
Date of Patent:
May 23, 2006
Assignee:
Academy of Military Medical Sciences Institute of Pharmacology and Toxicology
Inventors:
Yimin Zhao, Ming Yang, Yunfeng Li, Xinhui Luan, Zhipu Luo
Abstract: This invention provides improved polyamides comprising a hairpin loop derived from ?-aminobutyric acid which bind to the minor groove of a promoter regions of a DNA sequence. Binding of the polyamide to the DNA sequence of the promoter region inhibits expression of the requisite gene. The improvement relates to the use of R-2,4-diaminobutyric acid and derivatives of the 2-amino group to form the hairpin loop. The improved asymmetric hairpin provides for tighter binding of the polyamides to the minor groove of DNA and additionally provides an amine function for derivatizing polyamides by, for example, forming amide linkages. Such derivatives may serve to attach detectable labels to the polyamide.
Abstract: A photoactive moiety exhibiting an anisotropic transition dipole. The moiety exhibits emission of polarized light in response to energy absorption. In a preferred embodiment, the moiety comprises a particle from the group consisting of a crystalline arrangement of photoactive molecules and a photoactive nanocrystal. The moiety may include a matrix in which photoactive objects exhibiting an anisotropic emission dipole are embedded. The moiety may be photobleached to product the anisotropy and the photoactive objects may have a one dimensional transition dipole in their natural state.
Abstract: The present invention relates to an optical transmittance device including an optical fiber having a tilted incident plane and a silicon optical bench (SiOB) with a mirror plane. In accordance with the present invention, there provided an optical device, including: a substrate having a groove with a tilted surface, wherein the groove has a mirror plane on the tilted surface; a light emitting means aligned to the substrate; and an optical fiber including a tilted incident plane, wherein a reflected light from the mirror plane is incident to the tilted incident plane.
Type:
Grant
Filed:
December 31, 2002
Date of Patent:
May 23, 2006
Assignees:
Fionix Inc., Institute of Information Assessment
Abstract: A modified polypeptide corresponding to an envelope glycoprotein of a primate lentivirus is described. The polypeptide has been modified from the wild-type structure so that it has cysteine amino acid residues introduced to create disulfide bonds, a cavity is filled with hydrophobic amino acids, a Proresidue is introduced at a defined turn structure of the protein, or the hydrophobicity is increased across the interface between different domains, while retaining the overall 3-dimensional structure of a discontinuous conserved epitope of the wild-type protein. Preferably, the polypeptide has more than one of those characteristics. Preferably, the primate lentivirus is HIV, and the protein is HIV-1 gp120.
Type:
Grant
Filed:
November 10, 1998
Date of Patent:
May 23, 2006
Assignees:
Dana-Farber Cancer Institute, Inc., The Trustees of Columbia University in the City of New York
Inventors:
Joseph G Sodroski, Richard T. Wyatt, Peter D. Kwong, Wayne A. Hendrickson, Michael Farzan
Abstract: The invention relates to processes for converting amino acids and amides to desirable conversion products including pyrrolidines, pyrrolidinones, and other N-substituted products. L-glutamic acid and L-pyroglutamic acid provide general reaction pathways to numerous and valuable selective conversion products with varied potential industrial uses.
Abstract: The present invention provides an apparatus for solution component analysis and fabricating method thereof, by which a mixing channel, reaction channel, and measurement channel are formed as continuous micro-grooves on one substrate to implement the miniature apparatus for analyzing solution components, by which the apparatus is provided with portability facilitating access to a spot outside a laboratory to perform an instant sample analysis, and by which an optical system configuration for sample analysis can be simplified in a manner of facilitating an optical transfer by forming a transparent silicon oxide (SiO2) layer between a micro channel of the apparatus and an optical fiber to insert the optical fiber therein.
Type:
Grant
Filed:
October 28, 2004
Date of Patent:
May 23, 2006
Assignee:
Korea Electronics Technology Institute
Inventors:
Kwang Bum Park, Joon Shik Park, Kyu Sik Shin, Hyo Derk Park
Abstract: Genomic DNA and cDNA encoding GA 3?-hydroxylase were isolated from rice. When the expression of these genes was suppressed in rice plants, the plants became dwarfed compared with the wild type plants.
Type:
Grant
Filed:
December 20, 2000
Date of Patent:
May 23, 2006
Assignees:
National Institute of Agrobiological Sciences, Riken
Abstract: Background plasma electrons in a laser wake field are trapped and accelerated using a sharp downward density transition. A short and intense laser pulse travels through low density plasma with a sharp downward density transition. The density transition scale length is much smaller than the wavelength of a laser wake wave. As the laser wake wave passes the density transition, its wavelength increases suddenly so that some background plasma electrons are self-injected into the acceleration phase of the wake field and trapped and accelerated by the strong laser wake field.
Type:
Grant
Filed:
February 12, 2003
Date of Patent:
May 23, 2006
Assignee:
Korea Electrotechnology Research Institute
Inventors:
Hy-yong Suk, Guang-Hoon Kim, Jong-Uk Kim, Chang-Bum Kim, Hae-June Lee