Abstract: A guide for positioning an orthopaedic guide pin on a bone structure includes a base having an upper face, a lower face intended to bear against the bone structure, and a through-hole for the pin, said guide including several bearing members able to move in guide holes formed in the base, wherein each bearing member has a lower end facing the lower face and is able to be moved selectively between a retracted position inside the guide hole and at least one deployed position in which the bearing member protrudes from the lower face so as to have a salient lower end intended to bear against the bone structure in order to allow the base to be inclined.

Abstract: The present invention relates to a foundation reinforcing apparatus using a bracing-type supporting structure and a lateral prestressing device and a foundation reinforcing method using the same, wherein, in the foundation reinforcement used for remodeling construction that requires an extension of a building such as an apartment, the foundation reinforcing apparatus introduces lateral pre-stressing force into a bracing-type supporting structure to introduce a preloading load to a new pile of a new footing by using an upper supporting plate, which is connected to an existing vertical part and an existing slab, as a reaction bed and allows the new pile to share a load applied before and after the extension of the building so that reinforcement efficiency is increased, and thus construction is performed economically.

Abstract: Systems and methods for obtaining scattering images during computed tomography (CT) imaging are provided. Two gratings or grating layers can be disposed between the object to be imaged and the detector, and the gratings or grating layers can be arranged such that primary X-rays are blocked while scattered X-rays that are deflected as they pass through the object to be imaged reach the detector to generate the scattering image.

Abstract: An electrode and a lithium-ion battery employing the electrode are provided. The electrode includes an active layer, a conductive layer, and a non-conductive layer. The conductive layer is disposed on the top surface of the active layer. The conductive layer includes a first porous film and a conductive lithiophilic material, and the conductive lithiophilic material is within the first porous film and covers the inner surface of the first porous film. The non-conductive layer includes a second porous film and a non-conductive lithiophilic material, and the non-conductive lithiophilic material is within the second porous film and covers the inner surface of the second porous film. The conductive layer is disposed between the active layer and the non-conductive layer. The binding energy (?G) of the lithiophilic material with lithium is less than or equal to ?2.6 eV.

Abstract: A plurality of battery packs is provided in communication with an energy monitoring and control system. Each battery pack includes a plurality of battery cells that collectively dictate the capabilities of the battery pack. The energy monitoring and control system determines a plurality of pack charging or pack discharging parameters for each battery pack that, when performed, achieve one or more performance metrics at a user level (e.g., performance metrics of each battery pack within a system of multiple battery packs). The battery pack further determines a plurality of cell charging or cell discharging parameters for each battery cell based upon the determined plurality of pack charging or pack discharging parameters for each battery cell that, when performed, achieve one or more performance metrics at a battery level (e.g., performance metrics of different cells of each battery pack).

Abstract: The purpose of the present invention is to provide an ointment preparation in which both separation over time and discoloration over time are suppressed. Both separation over time and discoloration over time are suppressed in: a topical composition containing (A) 30-60 weight % of zinc chloride, a specific (B) inorganic powder and a specific (C) additive, and (D) a solvent; and a topical composition containing (A) 30-60 weight % of zinc chloride, a specific (B) inorganic powder, and (D) a solvent.

Abstract: A spherical 3D tumor spheroid according to an aspect has an appropriate diameter, roundness and specificity so as to be suitably used in vitro, and expresses an ECM structure similar to that of in vivo tumor, and thus may be used in evaluating the efficacy of drug for treating various types of tumors.

Abstract: A sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet including a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.

Abstract: Provided herein are methods and compositions for disrupting biofilms in vitro and in vivo. Also disclosed are antibodies comprising a specified heavy chain (HC) immunoglobulin variable domain sequence and/or a specified light chain (LC) immunoglobulin variable domain sequence.

Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide robust CRISPR-based nucleic acid amplification methods and systems. Embodiments disclosed herein can amplify both double-stranded and single-stranded nucleic acid targets. Moreover, the embodiments disclosed herein can be combined with various detection platforms, for example, CRISPR-SHERLOCK, to achieve detection and diagnostic with attomolar sensitivity. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Abstract: The present invention relates to the delivery of oligomers for treating patients with a 5? mutation in their DMD gene other than a DMD exon 2 duplication. The invention provides methods and materials for activating an internal ribosome entry site in exon 5 of the DMD gene resulting in translation of a functional truncated isoform of dystrophin. The methods and materials can be used for the treatment of muscular dystrophies arising from 5? mutations in the DMD gene such as Duchenne Muscular Dystrophy or Becker Muscular Dystrophy.

Abstract: An anti-scrubbing mechanism in the track of a tracked robot or a tracked vehicle is disclosed. In one embodiment, a tracked robot includes one or more tracks coupled to a chassis of the tracked robot. Each of the one or more tracks include one or more track segments along a length of each of the one or more tracks and a plurality of rollers coupled to the one or more track segments along the length of each of the one or more tracks, wherein each of the plurality of rollers and the one or more track segments are arranged alternately along a width of each of the one or more tracks. The tracked robot further includes a drive system mechanically coupled to the one or more tracks and the chassis of the tracked robot.

Abstract: A method for removing boron is provided, which includes (a) mixing a carbon source material and a silicon source material in a chamber to form a solid state mixture, (b) heating the solid state mixture to a temperature of 1000° C. to 1600° C., and adjusting the pressure of the chamber to 1 torr to 100 torr. The method also includes (c) conducting a gas mixture of a first carrier gas and water vapor into the chamber to remove boron from the solid state mixture, and (d) conducting a second carrier gas into the chamber.

Abstract: A real-time utterance verification system according to the present invention includes a speech recognition unit configured to recognize an utterance of an utterer, a memory configured to store a program for verifying the utterance of the utterer in real time, and a processor configured to execute the program stored in the memory, wherein, upon executing the program, the processor generates and stores a list of the utterance of the utterer, performs a semantic analysis on each utterance included in the list, and generates, when the utterance is determined to be an inappropriate utterance for a listener as a result of the semantic analysis, utterance restricting information corresponding to the inappropriate utterance.

Abstract: Manufacturing processes can be optimized using machine learning models. For example, a system can execute an optimization model to identify a recommended set of values for configurable settings of a manufacturing process associated with an object. The optimization model can determine the recommended set of values by implementing an iterative process using an objective function. Each iteration of the iterative process can include selecting a current set of candidate values for the configurable settings from within a current region of a search space defined by the optimization model; providing the current set of candidate values as input to a trained machine learning model that can predict a value for a target characteristic of the object or the manufacturing process based on the current set of candidate values; and identifying a next region of the search space to use in a next iteration of the iterative process based on the value.

Abstract: A method of manufacturing a semiconductor package and a semiconductor package in which positional alignment between a wafer and a substrate until the wafer is mounted and packaged on the substrate is achieved accurately. A wafer is mounted on a package substrate by using first alignment marks and D-cuts as benchmarks, and then a mold resin layer is formed on the wafer in a state in which the first alignment mark is exposed. A part of the mold resin layer is removed by using the D-cuts exposed from the mold resin layer as benchmarks, so that the first alignment marks can be visually recognized. A second alignment marks are formed on the mold resin layer by using the first alignment marks as benchmarks. A Cu redistribution layer to be conducted to a pad portion is formed on a mold resin layer by using the second alignment marks as benchmarks.

Abstract: The present invention relates to the technical field of polymer materials, and in particular, relates to a polyurethane polymer and a method for preparing the same and use thereof. The present invention discloses use of aminoimidazolinone-based compound in preparing an end-capped polyurethane polymer product, by which the polyurethane polymer capable of achieving repeated self-healing for multiple times without adding any self-healing agent and any external stimulation can be prepared. The present invention further provides a polyurethane polymer capable of achieving repeated self-healing for multiple times without any external stimulation and having a compressive strength restored to at most 96% of the one before compression, and a method for preparing the same.

Abstract: The present disclosure to an apparatus for membrane distillation using a solar absorber and a heat pump, in which in the implementation of a membrane distillation process for producing treated water using a temperature difference between raw water and a coolant, raw water is heated using the solar absorber with improved heat collection efficiency, and through this, the treated water production efficiency of the membrane distillation process is improved.

Abstract: The present disclosure pertains to a recombinant Corynebacterium glutamicum strain for production of glutaric acid and a method for production of glutaric acid by using the same. When used to produce glutaric acid, the recombinant Corynebacterium glutamicum strain guarantees an excellent output and allows the selective production of glutaric acid without generation of byproducts, which needs no isolation and purification processes and thus leads to an economical benefit. Consequently, the recombinant strain is useful for production of glutaric acid.

Abstract: A semiconductor device comprise a substrate, source/drain regions, a channel region, a gate dielectric layer and a gate conductive layer, wherein the gate dielectric layer comprises a barrier layer, a storage layer, a first interface layer, a tunneling layer, a second interface layer. In accordance with the semiconductor device and the manufacturing method of the present invention, an interface layer is added between the storage layer and tunneling layer in the gate dielectric by adjusting process step, and the peak concentration and peak location of nitrogen can be flexibly adjusted, effectively improving the quality of the interface between the storage layer and the tunneling layer in the gate dielectric layer, increasing process flexibility, improving device reliability and current characteristics.