Abstract: A microchannel heat exchanger structure with a nozzle and a working method thereof. The microchannel heat exchanger structure with a nozzle, includes a first heat exchange portion, a second heat exchange portion, and at least one nozzle portion between the first heat exchange portion and the second heat exchange portion, the first heat exchange portion having a high-pressure heat exchange channel, a first micro-fin array being provided inside the high-pressure heat exchange channel, and the second heat exchange portion having a low-pressure heat exchange channel, the high-pressure heat exchange channel and the low-pressure heat exchange channel being in communication through at least one nozzle disposed in the nozzle portion. The heat exchanger structure has a good heat exchange effect and can achieve a better heat flux during heat exchange.

Abstract: According to the present disclosure, an optical signal emitted from a single molecule is received to measure a central location of the single molecule while changing a phase of a structured illumination having a periodic pattern to measure a phase of a pattern in which a fluorescence intensity is periodically changed in accordance with a distance between the pattern and the single molecule while displacing the periodic pattern by a specific interval to measure the central location of the single molecule, thereby improving an accuracy of the central location of the single molecule with low photons and as a result, the resolution of the image may be enhanced.

Abstract: A wheel-leg mechanism is provided. The mechanism comprises a thigh, the upper end of the thigh is movably arranged in a mounting seat for a thigh motor, and is in transmission connection with a thigh motor, and the thigh motor is fixedly provided on one side of the mounting seat for a thigh motor; a shank motor is arranged at the side, away from the thigh motor, of the thigh, a suspension shock absorption system is connected to the shank motor, the shank motor is in transmission connection with a shank by a synchronous belt, the shank is movably connected to the tail end of the thigh, a wheel is movably mounted at the tail end of the shank, and the wheel is in transmission connection with a hub motor; and a braking system is provided on the wheel. A wheel-legged vehicle having the wheel-leg mechanism is further provided.

Abstract: Ventricular catheters and their methods of use are disclosed. In some embodiments, the disclosed ventricular catheters may reduce, or substantially prevent, obstruction of the catheter by astrocytes or other brain tissue due to adhesion and/or growth within the catheter. For example, in some embodiments, the holes and internal lumen of a ventricular catheter may be constructed such that the wall shear stresses applied within the holes and internal lumen of the catheter are greater than a threshold shear stress to prevent cell adhesion and growth within the catheter.

Abstract: The present invention relates to a composition for preventing or treating cancer, containing a novel trifluoromethyl phenyl pyrazole derivative as an active ingredient, and, more specifically, to a composition for preventing, alleviating or treating cancer and a radiosensitizer composition for treating cancer with radiotherapy, which contain, as an active ingredient, a novel sulfonamide derivative including N,N-dimethyl-N?-(3-(1-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)phenyl)azanesulfonamide. Novel sulfonamide derivatives according to the present invention have an excellent apoptotic effect on cancer cells, and thus are usable as an effective anti-cancer agent, and reduce the radioresistance of cancer cells, and thus can be used as a radiosensitizer composition during cancer treatment.

Abstract: Disclosed are compounds and pharmaceutically acceptable salts, hydrates, solvates, prodrugs, stereoisomers, or tautomers thereof that may cause degradation of various proteins e.g., IKZF2 (Helios). Also disclosed are pharmaceutical compositions containing same, and methods of making and using the compounds to treat diseases and disorders associated with Helios and which may benefit from Helios degradation.

Abstract: The present invention belongs to the field of genetic engineering. Specifically, the present invention relates to a gene editing system derived from Flavobacterium and uses thereof.

Abstract: A content patch encoding method and a content patch decoding method are provided. The content patch decoding method includes: receiving a bit stream, and obtaining multiple information corresponding to a point cloud patch and a mesh patch accordingly; obtaining a connectivity between multiple vertices of the mesh patch based on the bit stream; and reconstructing the point cloud patch and the mesh patch based on the information and the connectivity between the vertices.

Abstract: The present disclosure relates to antioxidant for a polymer electrolyte membrane fuel cell electrode catalyst, which includes cerium hydrogen phosphate (HCe2(PO4)3(H2O)) in the form of a nanofiber, and an electrode and a membrane-electrode assembly including the same. The electrode for a polymer electrolyte membrane fuel cell of the present disclosure, wherein the antioxidant is dispersed, can improve the mechanical strength of an electrode catalyst layer and can minimize deterioration of chemical durability even after long-term operation. And, a fuel cell including the same can exhibit high output performance and can operate stably even after long-term operation.

Abstract: The present invention relates to a novel use of milk exosomes, and more specifically, provides various uses of milk exosomes, such as in functional cosmetics, functional health food with various functions such as improving gut health and immunity, and drugs including a wound healing medication.

Abstract: A fluidized bed reactor, a device, and a method for producing low-carbon olefins from oxygen-containing compound are provided. The fluidized bed reactor includes a reactor shell, a reaction zone, a coke control zone and a delivery pipe, where there are n baffles arranged in the coke control zone, and the n baffles divide the coke control zone into n sub-coke control zones which include a first sub-coke control zone, a second sub-coke control zone, and an nth sub-coke control zone; at least one catalyst circulation hole is provided on each of the n-1 baffles, so that the catalyst flows in an annular shape in the coke control zone, where n is an integer. The device and method can be adapted to a new generation of DMTO catalyst, and the unit consumption of production ranges from 2.50 to 2.58 tons of methanol/ton of low-carbon olefins.

Abstract: Disclosed herein are an apparatus and method for extracting memory map information from firmware. The apparatus includes one or more processors and executable memory for storing at least one program executed by the one or more processors. The at least one program retrieves memory-related data from firmware, sets a data structure by analyzing binary code based on the memory-related data, and retrieves a memory map structure from the firmware using the data structure.

Abstract: Disclosed herein is a video decoding method including: obtaining a transform skip mode flag indicating whether transform/inverse transform is skipped in a current block; when transform/inverse transform is skipped in the current block according to the transform skip mode flag, determining that secondary transform/inverse transform is skipped in the current block; and when transform/inverse transform is not skipped in the current block according to the transform skip mode flag, obtaining a transform matrix index for secondary transform/inverse transform of the current block and, determining whether secondary transform/inverse transform is skipped in the current block based on the transform matrix index.

Abstract: A metallization stack and a method of manufacturing the same, and an electronic device including the metallization stack are provided. The metallization stack may include at least one interconnection line layer and at least one via hole layer arranged alternately on a substrate. At least one pair of adjacent interconnection line layer and via hole layer in the metallization stack includes: an interconnection line in the interconnection line layer, and a via hole in the via hole layer. The interconnection line layer is closer to the substrate than the via hole layer. A peripheral sidewall of a via hole on at least part of the interconnection line does not exceed a peripheral sidewall of the at least part of the interconnection line.

Abstract: A rotary electric machine control apparatus (1) suitably controls two inverters (10) connected to associated ends of open windings (8). The rotary electric machine control apparatus (1) performs target control involving: controlling a first one of the inverters (10), which is selected from a first inverter (11) and a second inverter (12), by rectangular wave control; and controlling a second one of the inverters (10) by special pulse width modulation control that is one type of pulse width modulation control. The special pulse width modulation control is a control method to produce a switching pattern (Su2+) that is based on a difference between a switching pattern resulting from the pulse width modulation control and a switching pattern (Su1+) resulting from the rectangular wave control when a target voltage is to be generated in the open windings (8).

Abstract: One embodiment provides a computing device for remote experiential teambuilding activities. The computing device includes a communication circuitry and a user interface (UI). The communication circuitry is configured to couple to a remote computing device via a network. The remote computing device is associated with a remote participant. The UI is configured to receive a local user input from a local participant, and to provide at least one of a local device output or a remote device output to the local participant. The local user input, local device output and remote device output are related to a selected experiential activity.

Abstract: The invention provides a method for preventing super large-scale floods and debris flows. First, the scale corresponding to certain standard floods in the watershed is evaluated based on field investigations and historical data. Second, the design standards of the system are chosen based on the prevention of super large-scale floods, and the design standard of critical control engineering is further determined. Finally, the design methods of check dams with different functional zones are proposed according to the design standards of critical control engineering. The invention allows part of the key control dam to fail under safe operating conditions of the entire system by increasing the cross-sectional areas and the flow discharges. The unbroken foundation of the dam can effectively control the channel entrainment and regulate the cross-sectional discharge. The design is helpful in mitigating giant floods and debris flows, thus protecting downstream infrastructures.

Abstract: Aqueous anolytes for redox flow batteries are disclosed. The anolytes include a fluorenone-fluorenol derivative, an additive comprising an organic compound including one or more proton acceptor groups, an alkali metal hydroxide, and water. The additive functions as a homogeneous organocatalyst and may increase the current density of an aqueous redox flow battery including the anolyte.

Abstract: Delivery systems and their methods of use for delivering one or more therapeutic compounds to a user are described. A delivery system may include an implantable pump and an external actuator. The implantable pump may include an actuatable portion that may be actuated to dispense a volume of fluid. The external actuator may include a pusher configured to deform skin to engage an actuatable portion of the pump. The external actuator may also include a positioning magnet configured to magnetically attract a portion of the implantable pump such that the external actuator and the pump may be aligned prior to applying force to the portion of the skin between the external actuator and the actuatable portion of the pump.

Abstract: Provided is a technology for implementing an AR optical waveguide display capable of showing a hologram image by means of a small and simple system configuration by using an HOE. A holographic display according to an embodiment of the present invention comprises: a light source module for emitting a beam; an optical waveguide through which the emitted beam is incident and propagated; a plurality of holographic optical elements (HOES) for propagating the beam incident to the optical waveguide inside the optical waveguide while totally reflecting the beam; and a modulator for reproducing a holographic image through the progressing beam and propagating the beam to the inside of the optical waveguide while totally reflecting the beam. Accordingly, it is possible to implement, as a small and simple system, an optical waveguide display showing an AR hologram by using an optical waveguide and an HOE.