Abstract: The present invention concerns the field of heart related disorders in NAFLD patients, and in particular relates to a method of treatment suitable for improving the conditions of heart injury and myocardial related damage in such patients. Cardiovascular diseases (CVD), including coronary heart disease and non-ischemic cardiomyopathy, are the leading cause of death in patients with NAFLD Silibinin administration markedly demonstrated an effectiveness on myocardial damage and an improvement of the myocardiocyte function reversing the accumulation of lipid droplets and consequently improving the condition of these patients.
Type:
Application
Filed:
December 20, 2012
Publication date:
June 26, 2014
Applicant:
Instituto Biochimico Italiano Giovanni Lorenzini S.p.A.
Abstract: A process for the preparation of sterile sodium amoxycillin characterized by the fact that a solution of amoxycillin trihydrate in a mixture of methyl alcohol and a lower C.sub.2 -C.sub.5 alcohol is reacted in a sterile ambient, optionally in the presence of a suitable amine, with a solution of a suitable salifying agent selected from the group consisting of an alcoholate or carboxylate of sodium in methyl acetate followed by separation of the precipitate is described.
Type:
Grant
Filed:
September 15, 1995
Date of Patent:
September 24, 1996
Assignee:
Instituto Biochimico Italiano Giovanni Lorenzini S.p.A.
Inventors:
Giordano B. Corsi, Alberto Brandt, Loredana Cecchetelli
Abstract: A slow-release pharmaceutical composition containing a bile acid as active ingredient and comprising at least one bioadhesive substance and at least one high specific gravity substance, an aliquot thereof being enteric coated and the remainder being non-enteric coated.
Type:
Grant
Filed:
May 2, 1994
Date of Patent:
April 23, 1996
Assignee:
Instituto Biochimico Italiano Giovanni Lorenzini S.p.A.
Inventors:
Fabio Borella, Alberto Brandt, Fabio Carli