Patents Assigned to Instituto Mexicano del Seguro Social
  • Patent number: 8563626
    Abstract: The purpose of the present invention is to demonstrate that semiconducting and non-biodegradable implants made with polypyrrole and polyethylenglycol copolymers and iodine-doped and plasma-synthesized pyrrole polymers, have a neuroprotector effect and induce the reconnection of the spinal cord after an injury; this effect was proved in a model involving a complete section of the spinal cord in rats; the results o the functional evaluation demonstrated 5 times greater recovery in animals implanted with the polypyrrole-polyethylenglycol copolymer compared with the control group which only underwent a complete section of the spinal cord; in addition, the functional recovery of the group with iodine-doped polypyrrole was ten times greater compared to the control group; in the histological study various inflammatory and immune cells were identified at the injury site in the three experimental groups with and without implants and the integration of the polymers in the nervous tissue of the spinal cord was also obse
    Type: Grant
    Filed: June 1, 2007
    Date of Patent: October 22, 2013
    Assignees: Universidad Autonoma Metropolitana, Instituto Nacional de Neurologia Y Neurocirugia Manuel Velasco Suarez, Instituto Mexicano del Seguro Social, Instituto Nacional de Investigaciones Nucleares
    Inventors: Roberto Olayo Gonzalez, Juan Morales Corona, Rodrigo Lozano Mondragon, Ana Laura Alvarez Mejia, Juan Carlos Axayacatl Morales Guadarrama, Luis Camilo Rios Castañeda, Maria de los Angeles Araceli Diaz Ruiz, Guillermo Jesús Cruz Cruz, María Guadalupe Olayo González, Hermelinda Salgado Ceballos