Patents Assigned to Instituto Nacional de Neurologia Y Neurocirugia Manuel Velasco Suarez
  • Multiresistant-tumour sensitiser
    Patent number: 11684592
    Abstract: The present invention refers to the use of the compound Cur-[G-2]-OH as a sensitizing agent in a wide range of multidrug-resistant tumors, especially glioblastoma, which are characterized by overexpression of the Nrf2 pathway.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: June 27, 2023
    Assignee: Instituto Nacional de Neurologia Y Neurocirugia Manuel Velasco Suarez
    Inventor: Irma Gabriela Gonzalez Herrera
  • COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF EPILEPSY
    Publication number: 20210180136
    Abstract: Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.
    Type: Application
    Filed: February 8, 2021
    Publication date: June 17, 2021
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, RIKEN, INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ, U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Antonio V. Delgado-Escueta, Kazuhiro Yamakawa, Toshimitsu Suzuki, Marco Tulio Medina-Hernandez, Maria Elisa Alonso Vilatela
  • COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF EPILEPSY
    Publication number: 20190062838
    Abstract: Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.
    Type: Application
    Filed: November 5, 2018
    Publication date: February 28, 2019
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, RIKEN, INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ, U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Antonio V. Delgado-Escueta, Kazuhiro Yamakawa, Toshimitsu Suzuki, Marco Tulio Medina-Hernandez, Maria Elisa Alonso Vilatela
  • COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF EPILEPSY
    Publication number: 20160076105
    Abstract: Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.
    Type: Application
    Filed: November 24, 2015
    Publication date: March 17, 2016
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, RIKEN, INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ, U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Antonio V. Delgado-Escueta, Kazuhiro Yamakawa, Toshimitsu Suzuki, Marco Tulio Medina-Hernandez, Maria Elisa Alonso Vilatela
  • Use of plasma-synthesised pyrrole-derived polymers for the neuroprotection and reconnection of the central nervous system
    Patent number: 8563626
    Abstract: The purpose of the present invention is to demonstrate that semiconducting and non-biodegradable implants made with polypyrrole and polyethylenglycol copolymers and iodine-doped and plasma-synthesized pyrrole polymers, have a neuroprotector effect and induce the reconnection of the spinal cord after an injury; this effect was proved in a model involving a complete section of the spinal cord in rats; the results o the functional evaluation demonstrated 5 times greater recovery in animals implanted with the polypyrrole-polyethylenglycol copolymer compared with the control group which only underwent a complete section of the spinal cord; in addition, the functional recovery of the group with iodine-doped polypyrrole was ten times greater compared to the control group; in the histological study various inflammatory and immune cells were identified at the injury site in the three experimental groups with and without implants and the integration of the polymers in the nervous tissue of the spinal cord was also obse
    Type: Grant
    Filed: June 1, 2007
    Date of Patent: October 22, 2013
    Assignees: Universidad Autonoma Metropolitana, Instituto Nacional de Neurologia Y Neurocirugia Manuel Velasco Suarez, Instituto Mexicano del Seguro Social, Instituto Nacional de Investigaciones Nucleares
    Inventors: Roberto Olayo Gonzalez, Juan Morales Corona, Rodrigo Lozano Mondragon, Ana Laura Alvarez Mejia, Juan Carlos Axayacatl Morales Guadarrama, Luis Camilo Rios Castañeda, Maria de los Angeles Araceli Diaz Ruiz, Guillermo Jesús Cruz Cruz, María Guadalupe Olayo González, Hermelinda Salgado Ceballos