Abstract: The use of dapsone is the first effective treatment against the disabling consequences associated with cerebral infarction in patients. Dapsone was evaluated as a neuroprotector in the cerebral infarction model produced by the occlusion of the middle cerebral artery in rats and in patients suffering from acute cerebral infarction caused by thromboembolism. In both studies, dapsone displayed a reduction of between 70 and 90% in the adverse effects which occur as a consequence of the infarction.
Type:
Grant
Filed:
March 16, 2004
Date of Patent:
September 18, 2012
Assignees:
Universidad Autonoma Metropolitana, Instituto Nacional de Neurologia y Neurocirurgia Manuel Velasco Suarez
Inventors:
Luis Camílo Ríos Castañeda, Marina Altagracia Martínez, Juan Nader Kawachi, Jaime Kravzov Jinich
Abstract: The use of dapsone is the first effective treatment against the disabling consequences associated with cerebral infarction in patients. Dapsone was evaluated as a neuroprotector in the cerebral infarction model produced by the occlusion of the middle cerebral artery in rats and in patients suffering from acute cerebral infarction caused by thromboembolism. In both studies, dapsone displayed a reduction of between 70 and 90% in the adverse effects which occur as a consequence of the infarction.
Type:
Application
Filed:
March 16, 2004
Publication date:
March 11, 2010
Applicants:
UNIVERSIDAD AUTÓNOMA METROPOLITANA, INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRURGIA MANUEL VELASCO SUAREZ
Inventors:
Luis Camílo Ríos Castañeda, Marina Altagracia Martínez, Juan Nader Kawachi, Jaime Kravzov Jinich