Patents Assigned to INSTITUTO NACIONAL DE SALUD
  • recombinant antigens, purification of polyclonal anti- IgG and IgY antibodies and detection
    Patent number: 11753439
    Abstract: The present invention relates to a stationary phase for the purification of polyclonal anti-Giardia IgG and IgY antibodies, as well as a method for purifying polyclonal anti-Giardia IgG and IgY antibodies by affinity chromatography. The invention also relates to the polyclonal anti-Giardia IgG and IgY antibodies purified by affinity chromatography, which specifically bind to the antigenic proteins CWP1, alpha-giardin 7.3 and kinesin 3. In an additional aspect, the invention relates to a method for diagnosing giardiasis by detection of Giardia in a specific sample, and a kit for diagnosing giardiasis in biological and environmental samples.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: September 12, 2023
    Assignee: Instituto Nacional de Salud
    Inventors: Ángela Liliana Albarracín Cárdenas, Adriana Arévalo Jamaica, Sofía Duque Beltrán, Fabio Leonardo Quintero Vargas, Cesar Augusto Ramírez Segura
  • GIARDIA RECOMBINANT ANTIGENS, PURIFICATION OF POLYCLONAL ANTI-GIARDIA IGG AND IGY ANTIBODIES AND GIARDIA DETECTION
    Publication number: 20200354401
    Abstract: The present invention relates to a stationary phase for the purification of polyclonal anti-Giardia IgG and IgY antibodies, as well as a method for purifying polyclonal anti-Giardia IgG and IgY antibodies by affinity chromatography. The invention also relates to the polyclonal anti-Giardia IgG and IgY antibodies purified by affinity chromatography, which specifically bind to the antigenic proteins CWP1, alpha-giardin 7.3 and kinesin 3. In an additional aspect, the invention relates to a method for diagnosing giardiasis by detection of Giardia in a specific sample, and a kit for diagnosing giardiasis in biological and environmental samples.
    Type: Application
    Filed: December 18, 2017
    Publication date: November 12, 2020
    Applicant: Instituto Nacional de Salud
    Inventors: Ángela Liliana ALBARRACÍN CÁRDENAS, Adriana ARÉVALO JAMAICA, Sofía DUQUE BELTRÁN, Fabio Leonardo QUINTERO VARGAS, Cesar Augusto RAMÍREZ SEGURA
  • Method for evaluating the sensitivity and specificity of fast malaria-diagnosis test kits
    Patent number: 9194869
    Abstract: The invention relates to a method for evaluating kits for rapid diagnosis of malaria, in order to determine or to test the sensitivity and specificity thereof. To that end, the reactive strips of the diagnostic kits are exposed to different concentrations of the malaria parasite in a method that allows data on sensitivity and specificity indicated on the technical sheet of the kit to be ascertained.
    Type: Grant
    Filed: November 25, 2011
    Date of Patent: November 24, 2015
    Assignee: INSTITUTO NACIONAL DE SALUD
    Inventor: Nancy Arrospide Velasco
  • METHOD FOR EVALUATING THE SENSITIVITY AND SPECIFICITY OF FAST MALARIA- DIAGNOSIS TEST KITS
    Publication number: 20140356883
    Abstract: The invention relates to a method for evaluating kits for rapid diagnosis of malaria, in order to determine or to test the sensitivity and specificity thereof. To that end, the reactive strips of the diagnostic kits are exposed to different concentrations of the malaria parasite in a method that allows data on sensitivity and specificity indicated on the technical sheet of the kit to be ascertained.
    Type: Application
    Filed: November 25, 2011
    Publication date: December 4, 2014
    Applicant: INSTITUTO NACIONAL DE SALUD
    Inventor: Nancy Arrospide Velasco