Abstract: The invention relates to an aptamer, the structure thereof comprising at least one nucleotide sequence 5?-GGCA(A/G)GGA-3?, that can specifically bind to the poly(A) hairpin of the 5?UTR region of the genome of the human immunodeficiency virus type 1 (HIV-1), providing the method for producing aptamers with said sequence by means of a combination of experimental techniques of in vitro selection of nucleic acids with computational techniques of sequence optimization. The invention also relates to a DNA gene structure for synthesizing said aptamers, preferably RNA. The invention further relates to the different uses of the above-mentioned aptamer, including the use thereof as a biosensor molecule for detecting and/or quantifying HIV-1, as an inhibitor of the production of viral particles of HIV-1, and to the application thereof in medicine, the invention also relating to a method for treating a disease caused by HIV-1, and to a pharmaceutical composition comprising said aptamer.

Abstract: The invention relates to an unmanned air vehicle control system and method, designed such that, in one mission mode, the vehicle follows the mission route. The system comprises means (400, 450) for storing data indicating at least one auxiliary route (4000, 4001, 4002, 4003), such that each of a plurality of the mission route segments (10, 20), is assigned at least part (30, 31, 32, 33) of at least one auxiliary route. Furthermore, the system comprises route change means (53) designed for, as a response to a mission abandonment event (52), determining which part of which auxiliary route is assigned to the mission route segment where the vehicle is located, such that the vehicle can change the mission route to the corresponding auxiliary route.

Abstract: This invention relates to a system for estimating the position, velocity and orientation of a vehicle, by determining the components of two noncollinear constant unit vectors b,b according to vehicle body axes; and determining the components of the noncollinear constant unit vectors {right arrow over (g)}t,{right arrow over (e)}t according to Earth's axes.