Abstract: Monomeric VHH domain derived from anti-VP6 camelid antibodies, dimeric domain, immunization method, and treatment method for rotavirus infections, wherein said domain may be any of the amino acid sequences shown in SEQ ID NO:1, SEQ ID NO:2 or SEQ ID NO:3, and wherein said domains bind to protein VP6 of Group A rotavirus.
Type:
Grant
Filed:
December 3, 2013
Date of Patent:
June 21, 2016
Assignee:
INSTITUTO NACIONAL DE TECHNOLOGIA AGROPECUARIA (INTA)
Inventors:
Thomas Surrey, Aurelien Olichon, Lorena Laura Garaicoeachea, Gisela Ariana Marcoppido, Gladys Viviana Parreño, Silvia Gómez Sebastián, José Angel Martínez Escribano, Andrés Wigdorovitz