Patents Assigned to Instituto per la Ricerca Scientifica e Applicata di Technologie Alimentari S.p.A
  • Process for the preparation of 2,5-dimethyl-4-hydroxy-3(2H)-furanone and its 2,5-dialkyl homologues
    Patent number: 4294767
    Abstract: 2,5-dialkyl-4-hydroxy-3(2H)-furanones having the formula: ##STR1## are obtained by the aldol condensation, under basic conditions, of a 2,5-dialkyl-dihydro-3(2H)-furanone with an aldehyde, R"CHO, and dehydration of the aldol to the corresponding exocyclic alkene: ##STR2## The alkene is then reacted with ozone in a participating solvent to give the hydroperoxy-hemiacetal which is reduced to the hemiacetal, this then being converted to the desired product by heating under reflux in acidic conditions in an inert atmosphere.
    Type: Grant
    Filed: August 21, 1980
    Date of Patent: October 13, 1981
    Assignee: Instituto per la Ricerca Scientifica e Applicata di Technologie Alimentari S.p.A
    Inventors: Emile H. Eschinasi, Enrico Castelli