Abstract: Provided is the use of antisense RNA and methods for the treatment, diagnosis and prophylaxis of cancer comprising administering said antisense RNA, particularly miRs 15 and 16 to a patient in need thereof.

Abstract: A media converter, a system and a method for converting packet based data into serial data and vice versa are provided. The media converter comprises a first interface configured to receive and provide a first type of data stream based on data packets, a second interface configured to receive and provide a second type of data stream based on a continuous serial bit stream, and a signal processor connected to the first and second interfaces and configured to convert said first type of data stream into said second type of data stream and vice versa on the basis of a block encoding/decoding algorithm and a line encoding/decoding algorithm. Thus, enhanced bit error rate may be obtained, thereby allowing the use of optical transmission channels of increased length.

Abstract: An anti-CEA scFv having an uncleaved Pel B leader sequence is surprisingly stable and is highly specific for CEA and CEACAM1.

Abstract: An anti-CEA scFv having an uncleaved Pel B leader sequence is surprisingly stable and is highly specific for CEA and CEACAM1.

Abstract: An electrically controlled optical oscillator for a single subcarrier optical phase-locked loop, which includes: an electrically controlled electrical oscillator having an input, which receives an electrical driving input signal, and an output, which supplies an electrical driving output signal that has a frequency that is a function of the electrical driving input signal; a continuous-wave laser source, which supplies an optical carrier; and an optical modulator, which has an optical input connected to the laser source and receives the optical carrier, an electrical input, which is connected to the output of the electrically controlled electrical oscillator and receives the electrical driving output signal, and an optical output that modulates the optical carrier with the electrical driving output signal and generates an optical modulated signal. The optical modulator generates an optical modulated signal with single optical subcarrier.

Abstract: A local positioning system comprises a plurality of sensor elements that may communicate with mobile units in a wireless fashion. The responsiveness of the mobile units is measured by yes/no answers and averaged so as to provide a measure of the distance of a mobile unit to a specified sensor element. Based on this measure and the known positions of the sensor element, the position of the mobile unit is estimated, for instance by a model of ideal springs.

Abstract: A media converter, a system and a method for converting packet based data into serial data and vice versa are provided. The media converter comprises a first interface configured to receive and provide a first type of data stream based on data packets, a second interface configured to receive and provide a second type of data stream based on a continuous serial bit stream, and a signal processor connected to the first and second interfaces and configured to convert said first type of data stream into said second type of data stream and vice versa on the basis of a block encoding/decoding algorithm and a line encoding/decoding algorithm. Thus, enhanced bit error rate may be obtained, thereby allowing the use of optical transmission channels of increased length.

Abstract: A local positioning system comprises a plurality of sensor elements that may communicate with mobile units in a wireless fashion. The responsiveness of the mobile units is measured by yes/no answers and averaged so as to provide a measure of the distance of a mobile unit to a specified sensor element. Based on this measure and the known positions of the sensor element, the position of the mobile unit is estimated, for instance by a model of ideal springs.

Abstract: The present invention is directed to a adjuvant peptide and uses to facilitate antigen absorption in the mucosa, particularly nasal tissue. Vaccine compositions for mucosal delivery include the adjuvant peptide and an antigen for inducing an immune response.

Abstract: The present invention relates to a method to block the invasion of normal, neoplastic inflammatory or immune cells, tissue infiltration, and/or oedema formation through inhibition or modulation of molecules and proteolytic enzymes such as—but not exclusively—MMPs, for the therapy of all diseases whose pathogenesis is related to the above processes, including tumours, non-neoplastic angioproliferative diseases, inflammatory diseases, or autoimmune diseases, the method being based on the use of inhibitors of the protease of the HIV virus (HIV-PI).

Abstract: The invention relates to a methods of obtaining and expanding a purified population of long-term repopulating hematopoietic stem cells. The invention also relates to the uses of a purified population of long-term repopulating hematopoietic stem cells.

Abstract: A monoclonal antibody that recognises a structurally continuous and extracellularly-located epitope of human P-glycoprotein is described. The monoclonal antibody has a continuous amino acid sequence, and a binding affinity for the P-glycoprotein which manifests in the ability to stain greater than 90% of live CEM-VBL10 cells in a flow cytometry assay.

Abstract: The device as per the invention consists of a low pressure lamp incorporating an appropriately positioned microwave generator within the cavity. With this arrangement it is possible to obtain within the low pressure lamp microwaves of power very much greater than that which can be obtained using known systems involving the introduction of microwaves via coaxial cable, and such as to ensure greater excitation of the atoms forming the plasma produced in the lamp, consequently increasing the sensitivity of the analytical apparatus and markedly lowering the detectability limit of trace elements.