Patents Assigned to Instrumentation Laboratory Company
  • Patent number: 12228565
    Abstract: An example blood cell lysis composition includes a buffer and a secondary alcohol ethoxylate at a concentration in the range of about 2.5 percent (%) to about 20% weight per volume (w/v). The secondary alcohol ethoxylate may include Tergitol™ TMN-100X or Tergitol™ 15-S-9. The composition may be configured to lyse at least 90% of blood cells in a blood sample.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: February 18, 2025
    Assignee: Instrumentation Laboratory Company
    Inventors: Miklos Erdosy, Hyoungsik Yim, Emily McDowell, Prasad V. A. Pamidi
  • Patent number: 12226776
    Abstract: Operations performed according to the example techniques described herein include controlling a probe to pierce a stopper of a container containing a substance, where the stopper provides an air-tight seal for the container, and where the air-tight seal supports an internal pressure in the container. The operations also include detecting the internal pressure based on information from a pressure sensor; determining that the internal pressure is not at a target pressure and, based on determining that the internal pressure is not at the target pressure, controlling the probe either to aspirate air from the container or to dispense air into the container in order to move the internal pressure toward the target pressure.
    Type: Grant
    Filed: November 4, 2021
    Date of Patent: February 18, 2025
    Assignee: Instrumentation Laboratory Company
    Inventors: Demetrio Sanchez-Martinez, Joshua Shreve
  • Publication number: 20240379198
    Abstract: An example method detecting a presence of one or more oral anticoagulants or intravenous (IV) direct thrombin inhibitors in a blood sample may include the following operations: receiving parameters that are based on viscoelastic tests; comparing the parameters to predefined threshold values, where the parameters and the predefined threshold values are based on an identity of the one or more oral anticoagulants or the IV direct thrombin inhibitors; and detecting, based on the comparing, the presence of the one or more oral anticoagulants or IV direct thrombin inhibitors in the blood sample. The viscoelastic tests are performed on portions of the blood sample to obtain the parameters. The viscoelastic tests include both a viscoelastic test based on Ecarin activation and a viscoelastic test with low tissue factor activation.
    Type: Application
    Filed: July 24, 2024
    Publication date: November 14, 2024
    Applicant: Instrumentation Laboratory Company
    Inventors: Simon Schäfer, Philipp Groene, Klaus Görlinger
  • Patent number: 12139741
    Abstract: The present disclosure relates to biocide compositions compatible with enzyme biosensors and methods for using same. More particularly, the disclosure relates to biocide compositions compatible with enzymes used for measuring creatine and creatinine levels.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: November 12, 2024
    Assignee: Instrumentation Laboratory Company
    Inventors: Dennis Robert Conlon, Prasad Pamidi
  • Patent number: 12092630
    Abstract: A device and method for analyte detection and analytes in a particulate bearing fluid such as whole blood having an instrument for partitioning the panicles from the fluid that is integrated with a detector for analyses of one or more particulate bearing fluid analytes while the particles in the particulate bearing fluid are partitioned.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: September 17, 2024
    Assignee: Instrumentation Laboratory Company
    Inventors: Hansong Zeng, Gert Blankenstein
  • Patent number: 12072329
    Abstract: A device and method for analyte detection and analytes in a particulate bearing fluid such as whole blood having an instrument for partitioning the particles from the fluid that is integrated with a detector for analyses of one or more particulate bearing fluid analytes while the particles in the particulate bearing fluid are partitioned.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: August 27, 2024
    Assignee: Instrumentation Laboratory Company
    Inventors: Hansong Zeng, Gert Blankenstein
  • Patent number: 12073926
    Abstract: An example method detecting a presence of one or more oral anticoagulants or intravenous (IV) direct thrombin inhibitors in a blood sample may include the following operations: receiving parameters that are based on viscoelastic tests; comparing the parameters to predefined threshold values, where the parameters and the predefined threshold values are based on an identity of the one or more oral anticoagulants or the IV direct thrombin inhibitors; and detecting, based on the comparing, the presence of the one or more oral anticoagulants or IV direct thrombin inhibitors in the blood sample. The viscoelastic tests are performed on portions of the blood sample to obtain the parameters. The viscoelastic tests include both a viscoelastic test based on Ecarin activation and a viscoelastic test with low tissue factor activation.
    Type: Grant
    Filed: September 21, 2021
    Date of Patent: August 27, 2024
    Assignee: Instrumentation Laboratory Company
    Inventors: Simon Schäfer, Philipp Groene, Klaus Görlinger
  • Patent number: 12050232
    Abstract: Systems and methods for probe tip heating are disclosed. An exemplary system for probe tip heating can include an enclosure enclosing a probe tip, a heating device, and a fan. The probe tip can be configured to access an internal volume of a stoppered container and to aspirate or dispense a material from or to the internal volume of the stoppered container. The heating device can be configured to heat air circulating within the enclosure. The fan can be positioned to circulate air within the enclosure to heat the tip of the probe.
    Type: Grant
    Filed: December 31, 2021
    Date of Patent: July 30, 2024
    Assignee: Instrumentation Laboratory Company
    Inventors: Chris Christoff, Joshua A. Shreve, Reed Hebert, Benjamin Newton
  • Patent number: 11986829
    Abstract: Described is an automated reagent dispensing cap and methods of use in an automated clinical analyzer for introducing one or more reagent components housed in the reagent dispensing cap into a container enclosing another reagent component with which it is combined to achieve a reagent useful for diagnostic testing.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: May 21, 2024
    Assignee: Instrumentation Laboratory Company
    Inventors: Gert Blankenstein, Hansong Zeng
  • Patent number: 11958084
    Abstract: A cleaning device, and method of using the same, for cleaning a probe. The device includes a body defining an inner chamber. An air intake is connected to at least one air channel through the body, the at least one air channel configured to allow air from the air intake to flow into the inner chamber and towards the inner chamber. A liquid intake is connected to at least one liquid channel through the body, the at least one liquid channel configured to allow liquid from the liquid intake to flow into the inner chamber.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: April 16, 2024
    Assignee: INSTRUMENTATION LABORATORY COMPANY
    Inventors: Jo-Ann Loh, Joshua Shreve, Chison Liu
  • Patent number: 11959907
    Abstract: A device and method for analyte detection and analytes in a particulate bearing fluid such as whole blood having an instrument for partitioning the particles from the fluid that is integrated with a detector for analyzes of one or more particulate bearing fluid analytes while the particles in the particulate bearing fluid are partitioned.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: April 16, 2024
    Assignee: INSTRUMENTATION LABORATORY COMPANY
    Inventors: Hansong Zeng, Gert Blankenstein
  • Patent number: 11761921
    Abstract: Disclosed herein are compositions for permeable outer diffusion control membranes for creatinine and creatine sensors and methods of making such membranes.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: September 19, 2023
    Assignee: INSTRUMENTATION LABORATORY COMPANY
    Inventor: Xiaoxian Xu
  • Patent number: 11745177
    Abstract: A system and method for lysing of whole blood for CO-Ox measurement uses a lysing chamber for acoustic lysing of whole blood in a module in which the lysing chamber is separate from a CO-Ox measurement chamber. The disclosed acoustic lysing system and method avoids the expense and complexity of chemical lysing methods and allows the whole blood sample to be lysed while under continuous flow through the lysing chamber. The acoustic lysing chamber is provided upstream from a CO-Ox measurement chamber. The separation of the lysing chamber from the Co-Ox measurement chamber provides freedom to arrange and orient various optical components and/or other CO-Ox measuring components around the CO-Ox measurement chamber. The decoupling of the lysing chamber from the CO-Ox measurement chamber allows for more efficient design of the ultrasonic lysing transducer and CO-Ox measurement optics.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: September 5, 2023
    Assignee: INSTRUMENTATION LABORATORY COMPANY
    Inventors: Brian Joseph Bosy, Josef Kerimo
  • Publication number: 20230213543
    Abstract: Systems and methods for probe tip heating are disclosed. An exemplary system for probe tip heating can include an enclosure enclosing a probe tip, a heating device, and a fan. The probe tip can be configured to access an internal volume of a stoppered container and to aspirate or dispense a material from or to the internal volume of the stoppered container. The heating device can be configured to heat air circulating within the enclosure.
    Type: Application
    Filed: December 31, 2021
    Publication date: July 6, 2023
    Applicant: Instrumentation Laboratory Company
    Inventors: Chris Christoff, Joshua A. Shreve, Reed Hebert, Benjamin Newton
  • Patent number: 11662329
    Abstract: Disclosed herein are compositions for permeable outer diffusion control membranes for creatinine and creatine sensors and methods of making such membranes.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: May 30, 2023
    Assignee: INSTRUMENTATION LABORATORY COMPANY
    Inventor: Xiaoxian Xu
  • Patent number: D1056723
    Type: Grant
    Filed: June 23, 2023
    Date of Patent: January 7, 2025
    Assignees: STRATEC SE, Instrumentation Laboratory Company
    Inventors: Ralf Wolf, Christopher Almy, Jr., Joshua A Shreve, Candice Bell, Benjamin E Newton
  • Patent number: D1064844
    Type: Grant
    Filed: June 21, 2023
    Date of Patent: March 4, 2025
    Assignees: STRATEC SE, Instrumentation Laboratory Company
    Inventors: Ralf Wolf, Christopher Almy, Jr., Joshua A Shreve, Candice Bell, Benjamin E Newton
  • Patent number: D1065583
    Type: Grant
    Filed: June 21, 2023
    Date of Patent: March 4, 2025
    Assignees: STRATEC SE, Instrumentation Laboratory Company
    Inventors: Ralf Wolf, Christopher Almy, Jr., Joshua A Shreve, Candice Bell, Benjamin E Newton
  • Patent number: D1066736
    Type: Grant
    Filed: June 21, 2023
    Date of Patent: March 11, 2025
    Assignees: STRATEC SE, Instrumentation Laboratory Company
    Inventors: Ralf Wolf, Christopher Almy, Jr., Joshua A Shreve, Candice Bell, Benjamin E Newton
  • Patent number: D1066737
    Type: Grant
    Filed: June 21, 2023
    Date of Patent: March 11, 2025
    Assignees: STRATEC SE, Instrumentation Laboratory Company
    Inventors: Ralf Wolf, Christopher Almy, Jr., Joshua A Shreve, Candice Bell, Benjamin E Newton