Patents Assigned to Instytut Medycyny Doswiadczalnej i Klinicznej im. M. Mossakowskiego PAN
  • Patent number: 8697898
    Abstract: A medical application of N-oleoyl-dopamine and 3?-O-methyl-N-oleoyl-dopamine for the production of a medication for treatment or prophylaxis of disturbances or states due to deficiency of dopamine, preferably chosen from the group covering oxygen deficiencies (hypoxia) in anesthetized and awake mammals, breathing with atmospheric oxygen (normoxia), for the respiratory responses to hypoxia in mammals, lack of dopamine binding to the membrane system in the mammalian brain, disturbances in metabolic pathways of dopamine metabolism, states of dopamine deficiencies provoked by morbid or genetic factors as well as under condition connected to the physiological process of aging of the organism, through the systemic introduction of the compound to the mammalian organism. A method of production of 3?-O-methyl-N-oleoyl-dopamine in vitro is also disclosed.
    Type: Grant
    Filed: November 23, 2011
    Date of Patent: April 15, 2014
    Assignees: Instytut Medycyny Doswiadczalnej i Klinicznej im. M. Mossakowskiego PAN, Uniwersytet Warszawski
    Inventors: Mieczyslaw Pokorski, Dominika Zajac, Zbigniew Czarnocki, Piotr Roszkowski
  • Publication number: 20130131361
    Abstract: A medical application of N-oleoyl-dopamine and 3?-O-methyl-N-oleoyl-dopamine for the production of a medication for treatment or prophylaxis of disturbances or states due to deficiency of dopamine, preferably chosen from the group covering oxygen deficiencies (hypoxia) in anesthetized and awake mammals, breathing with atmospheric oxygen (normoxia), for the respiratory responses to hypoxia in mammals, lack of dopamine binding to the membrane system in the mammalian brain, disturbances in metabolic pathways of dopamine metabolism, states of dopamine deficiencies provoked by morbid or genetic factors as well as under condition connected to the physiological process of aging of the organism, through the systemic introduction of the compound to the mammalian organism. A method of production of 3?-O-methyl-N-oleoyl-dopamine in vitro is also disclosed.
    Type: Application
    Filed: November 23, 2011
    Publication date: May 23, 2013
    Applicants: Uniwersytet Warszawski, Wydzial Chemii, Instytut Medycyny Doswiadczalnej i Klinicznej im. M. Mossakowskiego PAN
    Inventors: Mieczyslaw Pokorski, Dominika Zajac, Zbigniew Czarnocki, Piotr Roszkowski