Patents Assigned to Intabio
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Patent number: 12174144Abstract: Methods, devices, and systems for improving the quality of electrospray ionization mass spectrometer (ESI-MS) data are described, as are methods, devices, and systems for achieving improved correlation between chemical separation data and mass spectrometry data.Type: GrantFiled: October 11, 2022Date of Patent: December 24, 2024Assignee: Intabio, LLCInventors: Erik Gentalen, Steve Lacy, Scott Mack, Luc Bousse, Morten Jensen
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Patent number: 11573200Abstract: Devices and methods for characterization of analyte mixtures are provided. Some methods described herein include performing enrichment steps on a device before expelling enriched analyte fractions from the device for subsequent analysis. Also included are devices for performing these enrichment steps.Type: GrantFiled: August 3, 2020Date of Patent: February 7, 2023Assignee: INTABIO, LLCInventor: Erik Gentalen
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Patent number: 11285484Abstract: Methods, devices, and systems for performing a plurality of isoelectric focusing reactions in parallel are described. In some instances, the disclosed devices may be designed to perform isoelectric focusing or other separation reactions followed by further characterization of the separated analytes using mass spectrometry. The disclosed methods, devices, and systems provide for fast, accurate separation and characterization of protein analyte mixtures or other biological molecules by isoelectric point.Type: GrantFiled: February 24, 2020Date of Patent: March 29, 2022Assignee: Intabio, LLCInventors: Erik Gentalen, Eric Gwerder, Scott Mack
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Patent number: 11224875Abstract: Methods, devices, and systems for performing isoelectric focusing reactions are described. The systems or devices disclosed herein may comprise fixtures that have a membrane. In some instances, the disclosed devices may be designed to perform isoelectric focusing or other separation reactions followed by further characterization of the separated analytes using mass spectrometry. The disclosed methods, devices, and systems provide for fast, accurate separation and characterization of protein analyte mixtures or other biological molecules by isoelectric point.Type: GrantFiled: December 16, 2020Date of Patent: January 18, 2022Assignee: INTABIO, LLCInventors: Eric Gwerder, Scott Mack, Erik Gentalen, Luc Bousse, Don Wesley Arnold
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Patent number: 10870113Abstract: Methods, devices, and systems for performing isoelectric focusing reactions are described. The systems or devices disclosed herein may comprise fixtures that have a membrane. In some instances, the disclosed devices may be designed to perform isoelectric focusing or other separation reactions followed by further characterization of the separated analytes using mass spectrometry. The disclosed methods, devices, and systems provide for fast, accurate separation and characterization of protein analyte mixtures or other biological molecules by isoelectric point.Type: GrantFiled: March 3, 2020Date of Patent: December 22, 2020Assignee: INTABIO, INC.Inventors: Erik Gentalen, Scott Mack, Eric Gwerder, Luc Bousse
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Patent number: 10866246Abstract: Devices and methods for characterization of samples are provided. Samples may comprise one or more analytes. Some methods described herein include performing enrichment steps on a device. Some methods described herein include performing mobilization of analytes. Analytes may then be further processed and characterized.Type: GrantFiled: February 4, 2020Date of Patent: December 15, 2020Assignee: INTABIO, INC.Inventors: Scott Mack, Erik Gentalen
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Patent number: 10782264Abstract: Devices and methods for characterization of analyte mixtures are provided. Some methods described herein include performing enrichment steps on a device before expelling enriched analyte fractions from the device for subsequent analysis. Also included are devices for performing these enrichment steps.Type: GrantFiled: November 19, 2019Date of Patent: September 22, 2020Assignee: INTABIO, INC.Inventor: Erik Gentalen
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Patent number: 10591488Abstract: Devices and methods for characterization of samples are provided. Samples may comprise one or more analytes. Some methods described herein include performing enrichment steps on a device. Some methods described herein include performing mobilization of analytes. Analytes may then be further processed and characterized.Type: GrantFiled: January 29, 2019Date of Patent: March 17, 2020Assignee: Intabio, Inc.Inventors: Erik Gentalen, Scott Mack
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Patent number: 10514360Abstract: Methods, devices, and systems for improving the quality of electrospray ionization mass spectrometer (ESI-MS) data are described, as are methods, devices, and systems for achieving improved correlation between chemical separation data and mass spectrometry data.Type: GrantFiled: August 6, 2019Date of Patent: December 24, 2019Assignee: INTABIO, INC.Inventors: Erik Gentalen, Steve Lacy, Scott Mack, Luc Bousse, Morten Jensen
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Patent number: 10401324Abstract: Devices and methods for characterization of analyte mixtures are provided. Some methods described herein include performing enrichment steps on a device before expelling enriched analyte fractions from the device for subsequent analysis. Also included are devices for performing these enrichment steps.Type: GrantFiled: December 18, 2018Date of Patent: September 3, 2019Assignee: INTABIO, INC.Inventor: Erik Gentalen
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Patent number: 10209217Abstract: Devices and methods for characterization of analyte mixtures are provided. Some methods described herein include performing enrichment steps on a device before expelling enriched analyte fractions from the device for subsequent analysis. Also included are devices for performing these enrichment steps.Type: GrantFiled: September 19, 2017Date of Patent: February 19, 2019Assignee: Intabio, Inc.Inventor: Erik Gentalen
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Publication number: 20180003674Abstract: Devices and methods for characterization of analyte mixtures are provided. Some methods described herein include performing enrichment steps on a device before expelling enriched analyte fractions from the device for subsequent analysis. Also included are devices for performing these enrichment steps.Type: ApplicationFiled: September 19, 2017Publication date: January 4, 2018Applicant: Intabio, Inc.Inventor: Erik GENTALEN
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Publication number: 20170176386Abstract: Devices and methods for characterization of analyte mixtures are provided. Some methods described herein include performing enrichment steps on a device before expelling enriched analyte fractions from the device for subsequent analysis. Also included are devices for performing these enrichment steps.Type: ApplicationFiled: November 29, 2016Publication date: June 22, 2017Applicant: IntabioInventor: Erik GENTALEN