Abstract: The present invention is directed to methods of antimicrobial therapy for a patient infected with, or suspected of being infected with a microorganism that has mycolic acid structures in its outer membrane, said method comprising coadministering a betaine-like detergent and an antibiotic to said patient in an amount and for a length of time sufficient to kill said microorganism.
Abstract: The present invention is related to methods and compositions for susceptibility testing of bacteria containing mycolic acid structures using betaine-like detergents, and inducing the susceptibility of such bacteria using the same.
Abstract: Compositions containing long chain carboxybetaines, and their use in antimicrobial formulations, are described. The compositions and methods are especially useful against gram positive microorganisms such as Staphylococcus and gram negative microorganisms such as Escherichia, Salmonella and Pseudomonas.
Abstract: A method for the preparation of Mycobacteria from any liquid, semi solid or exotic source is described. The extracted Mycobacterial sample is suitable for detection by culture and amplification.