Patents Assigned to Intelect Medical, Inc.
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Patent number: 10434302Abstract: Electrode devices having directional electrodes for use in deep brain stimulation or other uses. In one aspect, an electrode assembly comprises an elongate lead and a lead guide that are engageable with each other in a coaxial relationship. When the elongate lead and the lead guide are engaged with each other, the two components are rotationally fixed in relation to each other. In another aspect, an elongate lead comprises a radiologically-visible feature for indicating the orientation of the elongate lead. In yet another aspect, an electrode system is capable of determining the position and/or orientation of an electrode positioned within a body. In other aspects, methods for electrically stimulating a target site in the body are disclosed.Type: GrantFiled: November 17, 2015Date of Patent: October 8, 2019Assignee: INTELECT MEDICAL, INC.Inventors: Keith Carlton, Alan Greszler, Scott Kokones
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Patent number: 9545510Abstract: Leads having directional electrodes thereon. Also provided are leads having directional electrodes as well as anchoring prongs to secure the electrodes to the leads. Also provided are leads with directional electrodes where all the electrodes have the same surface area. Methods of treating conditions and selectively stimulating regions of the brain such as the thalamus and cerebellum are also provided.Type: GrantFiled: June 23, 2015Date of Patent: January 17, 2017Assignee: Intelect Medical, Inc.Inventors: Scott Kokones, John Swoyer, Jesse Geroy
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Patent number: 9539425Abstract: A system for treating medical conditions by neuromodulation of one or more target sites in the nervous system. In certain embodiments, at least one of the target sites is the medial thalamic region, including the intralaminar nucleus and the adjacent white and grey matter. In certain embodiments, where there is more than one target site, the other target sites is elsewhere in the nervous system, including the globus pallidus interna, subthalamic nucleus, corpus callosum, cerebellum, cerebral cortex (including the premotor cortex, motor cortex, and sensory cortex), ventral striatum, lateral thalamus, substantia nigra, and pedunculopontine nuclei. The medical conditions include movement disorders or improvement of movement function, stroke, neuropsychiatric or neuropsychologic disorders, neurodevelopmental disorders, and pain. Methods for treating medical conditions by neuromodulation of the intralaminar nuclei either alone or in combination with another target site(s) is also provided.Type: GrantFiled: October 12, 2007Date of Patent: January 10, 2017Assignees: Intelect Medical, Inc., The Cleveland Clinic Foundation, Cornell Research Foundation, Inc.Inventors: Ali Rezai, Nicholas Schiff, Scott Kokones, Andre Machado, Sierra Farris
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Patent number: 9308372Abstract: A system and method for displaying a volume of activation (VOA) may include a processor that displays via a display device a model of a portion of a patient anatomy that includes anatomical structures, displays via the display device and overlying the display of the model a VOA associated by the processor with a set of anatomical stimulation parameter settings, the display of the VOA, and graphically identifies interactions between the displayed VOA and a first subset of the anatomical structures associated with one or more stimulation benefits and a second subset of the anatomical structures associated with one or more stimulation side effects, where the graphical identifications differ depending on whether the interaction is with the first subset or the second subset.Type: GrantFiled: March 14, 2013Date of Patent: April 12, 2016Assignee: Intelect Medical, Inc.Inventors: Troy Sparks, Jordan Barnhorst, David Arthur Blum, Keith Carlton, Scott Kokones, Engin Erdo{hacek over (g)}an, Brian James Hoffer, Arna Diana Ionescu, David Ari Lubensky
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Patent number: 9302110Abstract: A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set.Type: GrantFiled: June 29, 2015Date of Patent: April 5, 2016Assignee: Intelect Medical, Inc.Inventors: Scott Kokones, David Arthur Blum, Keith R. Carlton, Troy Sparks
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Patent number: 9220889Abstract: Electrode devices having directional electrodes for use in deep brain stimulation or other uses. In one aspect, an electrode assembly comprises an elongate lead and a lead guide that are engageable with each other in a coaxial relationship. When the elongate lead and the lead guide are engaged with each other, the two components are rotationally fixed in relation to each other. In another aspect, an elongate lead comprises a radiologically-visible feature for indicating the orientation of the elongate lead. In yet another aspect, an electrode system is capable of determining the position and/or orientation of an electrode positioned within a body. In other aspects, methods for electrically stimulating a target site in the body are disclosed.Type: GrantFiled: February 11, 2008Date of Patent: December 29, 2015Assignee: Intelect Medical, Inc.Inventors: Keith Carlton, Alan Greszler, Scott Kokones
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Patent number: 9089688Abstract: Leads having directional electrodes thereon. Also provided are leads having directional electrodes as well as anchoring prongs to secure the electrodes to the leads. Also provided are leads with directional electrodes where all the electrodes have the same surface area. Methods of treating conditions and selectively stimulating regions of the brain such as the thalamus and cerebellum are also provided.Type: GrantFiled: December 13, 2013Date of Patent: July 28, 2015Assignee: Intelect Medical, Inc.Inventors: Scott Kokones, John Swoyer, Jesse Geroy
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Patent number: 9084896Abstract: A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set.Type: GrantFiled: June 27, 2012Date of Patent: July 21, 2015Assignee: Intelect Medical, Inc.Inventors: Scott Kokones, David Arthur Blum, Keith Carlton, Troy Sparks
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Patent number: 9072905Abstract: A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set.Type: GrantFiled: May 15, 2009Date of Patent: July 7, 2015Assignee: Intelect Medical, Inc.Inventors: Scott Kokones, David Arthur Blum, Keith Carlton, Troy Sparks
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Patent number: 9050470Abstract: A therapy tracking system and method may include a processor that obtains physiological information regarding a patient and a time period during which a deep brain stimulation (DBS) therapy is conducted. The information may be organized into a plurality of sessions. The processor may arrange in a display device a separate representation of the information for each of at least a subset of the sessions, such that the sessions are presented in order of time.Type: GrantFiled: May 15, 2009Date of Patent: June 9, 2015Assignee: INTELECT MEDICAL, INC.Inventors: Keith Carlton, Jordan Barnhorst, David Arthur Blum, Alan Greszler, Scott Kokones, Troy Sparks, Engin Erdo{hacek over (g)}an, Brian James Hoffer, Arna Diana Ionescu, David Ari Lubensky
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Patent number: 9026217Abstract: A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set.Type: GrantFiled: August 23, 2011Date of Patent: May 5, 2015Assignee: Intelect Medical, Inc.Inventors: Scott Kokones, David Arthur Blum, Keith Carlton
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Patent number: 9002472Abstract: Methods, apparatuses, and software for operating such apparatuses, for neuromodulation in a live mammalian subject, such as a human patient, provide for applying electrical energy to a target site in the nervous system of the subject using a signal comprising a series of pulses, wherein the inter-pulse intervals are varied using the output of a deterministic, non-linear, dynamical system comprising one or more system control parameters. In certain embodiments, the target site may be a site in the brain involved in generalized CNS (central nervous system) arousal. The dynamical system may be capable of exhibiting chaotic behavior.Type: GrantFiled: February 26, 2010Date of Patent: April 7, 2015Assignees: Intelect Medical, Inc., The Rockefeller UniversityInventors: Scott Kokones, Bradford Curtis Fowler, Donald Pfaff, Amy Wells Quinkert
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Patent number: 8855773Abstract: A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set.Type: GrantFiled: August 23, 2011Date of Patent: October 7, 2014Assignee: Intelect Medical, Inc.Inventors: Scott Kokones, David Arthur Blum, Keith Carlton, Troy Sparks
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Patent number: 8849632Abstract: A system and method for displaying a volume of activation (VOA) may include a processor that displays via a display device a model of a portion of a patient anatomy that includes anatomical structures, displays via the display device and overlying the display of the model a VOA associated by the processor with a set of anatomical stimulation parameter settings, the display of the VOA, and graphically identifies interactions between the displayed VOA and a first subset of the anatomical structures associated with one or more stimulation benefits and a second subset of the anatomical structures associated with one or more stimulation side effects, where the graphical identifications differ depending on whether the interaction is with the first subset or the second subset.Type: GrantFiled: May 15, 2009Date of Patent: September 30, 2014Assignee: Intelect Medical, Inc.Inventors: Troy Sparks, Jordan Barnhorst, David Arthur Blum, Keith Carlton, Scott Kokones, Engin Erdo{hacek over (g)}an, Brian James Hoffer, Arna Diana Ionescu, David Ari Lubensky
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Patent number: 8831731Abstract: A system and method for providing a volume of activation (VOA) of a stimulation electrode leadwire may include a processor that calculates a VOA for each of a plurality of sets of parameter settings of the leadwire, stores in a database each of the calculated VOAs in association with the respective set of parameter settings for which it was calculated, obtains a set of parameter settings of the leadwire for a stimulation, and determines a VOA for the obtained set of parameter settings based on the stored VOAs.Type: GrantFiled: May 15, 2009Date of Patent: September 9, 2014Assignee: Intelect Medical, Inc.Inventors: David Arthur Blum, Keith Carlton, Alan Greszler, Scott Kokones, Troy Sparks
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Patent number: 8825153Abstract: A stimulation system can have a first sensor to generate a first reading and a second sensor to generate a second reading. An analysis module of a programmer such as a patient programmer, which programs a stimulation signal to be delivered to a patient, conducts an evaluation of the patient based on the first and second readings. Evaluations may include determinations such as range of motion determinations, posture determinations, physical task-specific brain activity determinations, cognitive task-specific brain activity determinations, and brain activity-specific movement determinations.Type: GrantFiled: August 21, 2012Date of Patent: September 2, 2014Assignee: Intelect Medical, Inc.Inventors: Scott Kokones, Keith Carlton, Alan Greszler
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Patent number: 8812123Abstract: A patient programmer can have a progress module, wherein the progress module may obtain progress input from a patient in which the generator is implanted. The progress module may include sensors that are able to obtain progress input based on patient interactions with sensors coupled to the patient programmer. The progress module may also include an interface that poses progress-related questions to the patient and obtains responses to the questions from the patient. The patient programmer is also able to store the progress input for reporting purposes.Type: GrantFiled: October 17, 2007Date of Patent: August 19, 2014Assignee: Intelect Medical, Inc.Inventors: Keith Carlton, Scott Kokones
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Patent number: 8805515Abstract: Methods of neuromodulation in a live mammalian subject, such as a human patient. The method comprises applying an electrical signal to a target site in the nervous system, such as the brain, where the electrical signal comprises a series of pulses. The pulses includes a waveform shape that is more energy-efficient as compared to a corresponding rectangular waveform. Non-limiting examples of such energy-efficient waveforms include linear increasing, linear decreasing, exponential increasing, exponential decreasing, and Gaussian waveforms. Also described are apparatuses for neuromodulation and software for operating such apparatuses.Type: GrantFiled: April 11, 2013Date of Patent: August 12, 2014Assignee: Intelect Medical, Inc.Inventors: Randall York, Scott Kokones, Keith Carlton, Alan Greszler
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Publication number: 20140107744Abstract: Leads having directional electrodes thereon. Also provided are leads having directional electrodes as well as anchoring prongs to secure the electrodes to the leads. Also provided are leads with directional electrodes where all the electrodes have the same surface area. Methods of treating conditions and selectively stimulating regions of the brain such as the thalamus and cerebellum are also provided.Type: ApplicationFiled: December 13, 2013Publication date: April 17, 2014Applicant: INTELECT MEDICAL, INC.Inventors: Scott KOKONES, John SWOYER, Jesse GEROY
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Patent number: 8676342Abstract: A lead extension useful in deep brain stimulation treatment includes a body portion having a distal end and a proximal end, wherein the proximal end receives a stimulation signal from a generator. A lead interface is disposed at the distal end to send the stimulation signal to a brain stimulation lead. The lead extension also includes a sensor interface disposed at the distal end to receive an input signal from a sensor that is detached from the stimulation lead and send the input signal to the generator.Type: GrantFiled: August 19, 2011Date of Patent: March 18, 2014Assignee: Intelect Medical, Inc.Inventors: Scott Kokones, Keith Carlton