Patents Assigned to Intellipharmaceutics Corp
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Patent number: 10960077Abstract: A liquid or semi-solid matrix or magma or paste which is non-newtonian, thixotropic and pseudoplastic and composed of one or more controlled release agent, and/or one or more clays such as bentonite and/or one or more fillers in a non aqueous vehicle, and optionally materials selected from disintegrants, humectants, surfactants and stabilizers. The composition and physicochemical properties makes it harder or prevents dose dumping of narcotic analgesics in the presence of alcohol and harder to abuse opiod agonists or narcotic analgesics and discourages drug abuse via crushing, milling or grinding the dosage form to powder or heating the dosage form to vapour and snorting or inhalation by the nasal route or dissolving to abuse via the parenteral route.Type: GrantFiled: May 12, 2006Date of Patent: March 30, 2021Assignee: Intellipharmaceutics Corp.Inventors: Isa Odidi, Amina Odidi
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Patent number: 10653776Abstract: Drug delivery formulations, uses thereof and methods of making same are provided in order to reduce the potential for abuse, misuse or improper administration of an addictive substance or any active substance and to prevent, reduce, inhibit, or delay purposeful or accidental overdose of an active substance by ingesting too many dosage forms at once, for example.Type: GrantFiled: March 19, 2019Date of Patent: May 19, 2020Assignee: Intellipharmaceutics Corp.Inventor: Isa Odidi
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Patent number: 10632205Abstract: A pharmaceutical paste composition comprising an active ingredient such as an addictive substance, a controlled release agent, and a pharmaceutically suitable aqueous or non-aqueous carrier. The composition may comprise one or more of a clay, or an oily, waxy, or fatty substance. The composition may be filled into a capsule or other dispensing device. The composition may reduce dose dumping of an active ingredient. Methods of making and using the composition are also described.Type: GrantFiled: May 29, 2015Date of Patent: April 28, 2020Assignee: INTELLIPHARMACEUTICS CORPInventors: Isa Odidi, Amina Odidi
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Patent number: 10624858Abstract: The present invention is concerned with the use of transition coating and transition coating composition to control and or target the release of active pharmaceutical ingredients, and biological, chemical, neutraceutical, agricultural and nutritional materials and a method of preparing controlled release systems utilizing these components.Type: GrantFiled: August 23, 2004Date of Patent: April 21, 2020Assignee: INTELLIPHARMACEUTICS CORPInventors: Isa Odidi, Amina Odidi
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Patent number: 10293046Abstract: Drug delivery formulations, uses thereof and methods of making same are provided in order to reduce the potential for abuse, misuse or improper administration of an addictive substance or any active substance and to prevent, reduce, inhibit, or delay purposeful or accidental overdose of an active substance by ingesting too many dosage forms at once, for example.Type: GrantFiled: May 23, 2017Date of Patent: May 21, 2019Assignee: INTELLIPHARMACEUTICS CORP.Inventor: Isa Odidi
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Publication number: 20180333362Abstract: The disclosure is directed to drug delivery devices that provide for combinations of extended- and pulsed controlled release delivery of active pharmaceutical ingredient(s) APIs. The described drug delivery devices for oral administration of therapeutic compositions can include two or more populations of unit dosage forms including one or more API's in various combinations of pulsed and delayed/extended delivery formulations. The population of unit dosage forms are provided in a variety of different vehicles such as granules, beads, pellets, or tablets and can be contained within a drug delivery device of the present disclosure.Type: ApplicationFiled: July 31, 2018Publication date: November 22, 2018Applicant: INTELLIPHARMACEUTICS CORP.Inventors: ISA ODIDI, AMINA ODIDI
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Patent number: 10064828Abstract: The disclosure is directed to drug delivery devices that provide for combinations of extended and pulsed controlled release delivery of active pharmaceutical ingredient(s) APIs. The described drug delivery devices for oral administration of therapeutic compositions can include two or more populations of unit dosage forms including one or more API's in various combinations of pulsed and delayed/extended delivery formulations. The population of unit dosage forms are provided in a variety of different vehicles such as granules, beads, pellets, or tablets and can be contained within a drug delivery device of the present disclosure.Type: GrantFiled: December 23, 2005Date of Patent: September 4, 2018Assignee: INTELLIPHARMACEUTICS CORP.Inventors: Isa Odidi, Amina Odidi
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Patent number: 9636306Abstract: An oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a first population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a first rate; a population of a basic substance; and a second population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a second rate. In another embodiment, the oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a population of a pharmaceutical active; a population of a basic substance; a population of enteric coated pharmaceutical active; and a population of enteric coated basic substance. The composition can provide multiple site specific delivery of a pharmaceutical active in a rapid, delayed and/or sustained release manner into the plasma.Type: GrantFiled: July 10, 2014Date of Patent: May 2, 2017Assignee: INTELLIPHARMACEUTICS CORP.Inventors: Isa Odidi, Amina Odidi
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Publication number: 20140322312Abstract: An oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a first population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a first rate; a population of a basic substance; and a second population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a second rate. In another embodiment, the oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a population of a pharmaceutical active; a population of a basic substance; a population of enteric coated pharmaceutical active; and a population of enteric coated basic substance. The composition can provide multiple site specific delivery of a pharmaceutical active in a rapid, delayed and/or sustained release manner into the plasma.Type: ApplicationFiled: July 10, 2014Publication date: October 30, 2014Applicant: INTELLIPHARMACEUTICS CORPInventors: Isa Odidi, Amina Odidi
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Patent number: 8802139Abstract: An oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a first population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a first rate; a population of a basic substance; and a second population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a second rate. In another embodiment, the oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a population of a pharmaceutical active; a population of a basic substance; a population of enteric coated pharmaceutical active; and a population of enteric coated basic substance. The composition can provide multiple site specific delivery of a pharmaceutical active in a rapid, delayed and/or sustained release manner into the plasma.Type: GrantFiled: June 3, 2004Date of Patent: August 12, 2014Assignee: Intellipharmaceutics Corp.Inventors: Isa Odidi, Amina Odidi
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Patent number: 8603520Abstract: An oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a first population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a first rate; a population of a basic substance; and a second population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a second rate. In another embodiment, the oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a population of a pharmaceutical active; a population of a basic substance; a population of enteric coated pharmaceutical active; and a population of enteric coated basic substance. The composition can provide multiple site specific delivery of a pharmaceutical active in a rapid, delayed and/or sustained release manner into the plasma.Type: GrantFiled: January 29, 2010Date of Patent: December 10, 2013Assignee: Intellipharmaceutics Corp.Inventors: Isa Odidi, Amina Odidi
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Publication number: 20130095176Abstract: A controlled release delivery composition comprising: a housing adapted for oral administration; and a plurality of discrete vehicles assembled within the housing, each of the vehicles are not compressed together, each of the vehicles being a bead, a pellet, a tablet, and/or granules compressed into a preselect shape, wherein each of the vehicles comprise a different combination and/or amount of an active agent, an amino acid, a buffer, and a polymer, such that each of the vehicles comprises a different active agent and/or release property from each other, wherein each of the vehicles releases the active agent independently of each other, and wherein each of the vehicles remains independent from each other and intact within the housing prior to oral administration of the delivery composition.Type: ApplicationFiled: September 25, 2012Publication date: April 18, 2013Applicant: Intellipharmaceutics Corp.Inventor: Intellipharmaceutics Corp.
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Patent number: 8394409Abstract: A controlled extended drug release technology for the controlled extended release of hydrophobic or hydrophilic drugs or therapeutically active agents consisting of a homogeneous blend of one or more therapeutic agents, gas generators and surrounded by one or more layers of coat made of thermoplastic water insoluble cellulose derivatives, acrylic polymers, superdisintegrants and optionally an oil, antioxidants and electrolytes. The technology platform is capable of releasing therapeutic agents via zero, first or pseudo first order release.Type: GrantFiled: July 1, 2004Date of Patent: March 12, 2013Assignee: Intellipharmaceutics Corp.Inventors: Isa Odidi, Amina Odidi
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Patent number: 6800668Abstract: The invention relates to methods for preparing a syntactic foam composition suitable for use as a carrier for chemicals or other compounds, including pharmaceuticals. The invention further relates to compositions prepared in accordance with the methods of the present invention.Type: GrantFiled: January 19, 2001Date of Patent: October 5, 2004Assignee: Intellipharmaceutics Corp.Inventors: Isa Odidi, Amina Odidi
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Patent number: 6676966Abstract: An extended release formulation of metformin hydrochloride is disclosed. The metformin hydrochloride is encased within polymeric film layers providing for gradual release of the metformin hydrochloride for over 12 and even 24 hours in the gastrointestinal tract and the blood plasma.Type: GrantFiled: May 1, 2001Date of Patent: January 13, 2004Assignee: Intellipharmaceutics Corp.Inventors: Amina Odidi, Isa Odidi
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Patent number: 6652882Abstract: The present invention relates to a controlled release pharmaceutical formulation comprising an effective amount of an active ingredient and from about 1% to about 70% by weight of an uncrosslinked polymer, a crosslinked insoluble polymer or a mixture of uncrosslinked and crosslinked polymers.Type: GrantFiled: October 5, 1998Date of Patent: November 25, 2003Assignee: Intellipharmaceutics CorpInventors: Isa Odidi, Amina Odidi