Abstract: The present disclosure provides a device having a circuit. The circuit includes at least one boost converter receiving power from an energy source, a square wave driver in series with the boost converter, an inductor in series with the square wave driver for converting a square wave to a sinusoidal wave, and a piezoelectric transducer in series with the inductor, the piezoelectric transducer connectable to a load. The device further includes a phase-locked loop coupled to the circuit to determine a resonance frequency of the piezoelectric transducer when the piezoelectric transducer is connected to the load.

Abstract: A vascular graft device includes a semipermeable inner wall surrounding a passage. A nonpermeable outer wall surrounds the inner wall. A biological agent is disposed between the inner and outer walls for release through the inner wall.

Abstract: A vascular graft device includes a semipermeable inner wall surrounding a passage. A nonpermeable outer wall surrounds the inner wall. A biological agent is disposed between the inner and outer walls for release through the inner wall.

Abstract: A biological agent delivery device for delivering biological agents includes a sheath having a longitudinally extending wall surrounding an interior region, and a closed tip at a distal end. A flexible pouch formed in the sheath wall for containing a biological agent is capable of being displaced radially outwardly for radially displacing the biological agent.

Abstract: A device for delivering biological agents includes a cannula for insertion into tissue having a distal end with a notch formed therein. A flexible membrane extending across the cannula notch has a surface for supporting a quantity of a biological agent. A temperature controlled fluid is disposed within the cannula for displacing the support surface of the membrane laterally with respect to the cannula to deliver the biological agent with precision to a tissue site or body cavity.

Abstract: A device for delivering biological agents includes a cannula for insertion into tissue having a distal end with a notch formed therein. A flexible membrane extending across the cannula notch has a surface for supporting a quantity of a biological agent. A displacement member is disposed within the cannula for displacing the support surface of the membrane laterally with respect to the cannula to deliver the biological agent with precision to a tissue site or body cavity.

Abstract: A unitary, flexible, substantially noncollapsible catheter tube of biocompatible material is comprised of hard and soft regions. The hard regions can be ring shaped or helical. The hard regions provide sufficient rigidity to the tube to prevent collapse under normal usage as the interior and exterior pressures vary. The soft regions provide sufficient flexibility to allow contoured placement of the tube. The hard regions can be created by exposing a polymer in the tube to radiation. The hard regions can also be created by periodically adding a harder material to the tube.

Abstract: A subcutaneous drug delivery device having a driving member for advancing a piston, concentrically enclosed by a cannula, to deliver a drug pellet to a subcutaneous tissue site. The piston has a recessed distal platform upon which the pellet rests for delivery when the distal end of the piston is exposed beyond the cannula.

Abstract: A subcutaneous drug delivery device having a driving member for advancing a piston, concentrically enclosed by a cannula, to deliver a drug pellet to a subcutaneous tissue site. The piston has a recessed distal platform upon which the pellet rests for delivery when the distal end of the piston is exposed beyond the cannula.

Abstract: A subcutaneous drug delivery device having a driving member for advancing a piston, concentrically enclosed by a cannula, to deliver a drug pellet to a subcutaneous tissue site. The piston has a recessed distal platform upon which the pellet rests for delivery when the distal end of the piston is exposed beyond the cannula.

Abstract: A unitary, flexible, substantially noncollapsible catheter tube of biocompatible material is comprised of hard and soft regions. The hard regions can be ring shaped or helical. The hard regions provide sufficient rigidity to the tube to prevent collapse under normal usage as the interior and exterior pressures vary. The soft regions provide sufficient flexibility to allow contoured placement of the tube. The hard regions can be created by exposing a polymer in the tube to radiation. The hard regions can also be created by periodically adding a harder material to the tube.

Abstract: A unitary, flexible, substantially noncollapsible catheter tube of biocompatible material is comprised of hard and soft regions. The hard regions can be ring shaped or helical. The hard regions provide sufficient rigidity to the tube to prevent collapse under normal usage as the interior and exterior pressures vary. The soft regions provide sufficient flexibility to allow contoured placement of the tube. The hard regions can be created by exposing a polymer in the tube to radiation. The hard regions can also be created by periodically adding a harder material to the tube.

Abstract: An occluder for a prosthetic heart valve assembly adapted within a seating-ring passage having a body including a downstream sealing section comprising a plurality of cuspids which engage each other to define a closed sealing section when the occluder is in its closed position and which flex outwardly relative to each other when the occluder is in its open position to define a central open passage through the occluder, and an armature reinforcing the body. The armature includes an annular ring and a plurality of reinforcing arms hingedly connected to the ring and extending through each cuspid to permit flexure of each arm relative to the annular ring.