Patents Assigned to INTERIUS BIOTHERAPEUTICS, INC.
  • Mutated polypeptides, compositions comprising the same, and uses thereof
    Patent number: 12252512
    Abstract: Provided for herein are viral particles comprising a heterologous viral glycoprotein and a targeting moiety, wherein the targeting moiety comprises a polypeptide comprising a formula of T-S1, wherein T is a target binding domain and S1 is a stalk portion. The stalk portion may comprise a variant Fe domain. The stalk portion may comprise a flexible polypeptide domain. The targeting moiety comprising the formula T-S1 may be incorporated into a viral particle to assist with targeting such particles to a specific cell type. Also provided for herein are compositions comprising the same, and methods of using the same.
    Type: Grant
    Filed: July 25, 2023
    Date of Patent: March 18, 2025
    Assignee: Interius Biotherapeutics, Inc.
    Inventors: Bruce C. Schnepp, Philip R. Johnson
  • Pseudotyped viral particles, compositions comprising the same, and uses thereof
    Patent number: 12104177
    Abstract: Provided for herein are mutant VSV-G polypeptides, compositions comprising the same, and methods of using the same. Also provided for herein are polypeptides and compositions that bind to CD7 and uses thereof. Also provided for herein are polypeptides and compositions that bind to CD8 and uses thereof.
    Type: Grant
    Filed: January 20, 2023
    Date of Patent: October 1, 2024
    Assignee: Interius Biotherapeutics, Inc.
    Inventors: Ronnie M. Russell, Philip R. Johnson
  • Pseudotyped viral particles, compositions comprising the same, and uses thereof
    Patent number: 12018292
    Abstract: Provided for herein are mutant VSV-G polypeptides, compositions comprising the same, and methods of using the same. Also provided for herein are polypeptides and compositions that bind to CD7 and uses thereof. Also provided for herein are polypeptides and compositions that bind to CD8 and uses thereof.
    Type: Grant
    Filed: January 20, 2023
    Date of Patent: June 25, 2024
    Assignee: Interius Biotherapeutics, Inc.
    Inventors: Ronnie M. Russell, Philip R. Johnson
  • Pseudotyped viral particles, compositions comprising the same, and uses thereof
    Patent number: 11767366
    Abstract: Provided for herein are mutant VSV-G polypeptides, compositions comprising the same, and methods of using the same. Also provided for herein are polypeptides and compositions that bind to CD7 and uses thereof. Also provided for herein are polypeptides and compositions that bind to CD8 and uses thereof.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: September 26, 2023
    Assignee: INTERIUS BIOTHERAPEUTICS, INC.
    Inventors: Ronnie M. Russell, Philip R. Johnson