Abstract: The invention relates to an extract and/or one or more natural compounds from plants or parts of plants, respectively, from a genus selected from Schisandra, Illicium, Kadsura, Steganotaenia or Magnolia, for the regulation of body weight, fat loss, and/or management of obesity, in humans or in animals, methods and uses of the same and to the use of the same or mixtures in the manufacture of a pharmaceutical or nutraceutical formulation. The above can further be used to reduce one or more adverse metabolic parameters in a subject. The invention relates also to said extract and/or compound(s) in the treatment or in the preparation of a medicament for treatment of obesity, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations comprising said extract and/or natural compound(s), which are useful in the regulation of body weight and/or fat loss and/or for the management of obesity.
Abstract: A compound of the formula I, wherein the symbols are as defined in the remaining specification, or a mixture of two or more compounds of the formula I, for use as active ingredient in the therapeutic—including prophylactic—treatment of a warm-blooded animal for the regulation of body weight (preferred) and/or fat loss (preferred) and/or for the management of obesity and/or for improving the total cholesterol HDL/LDL ratio; where the compound(s) of the formula I may be present in free form, in the form of a pharmaceutically and/or nutraceutically acceptable salt, in the form of tautomers, in the form of esters and/or in the form of solvates, as well as related invention embodiments.
Type:
Application
Filed:
January 13, 2011
Publication date:
January 24, 2013
Applicant:
INTERMED DISCOVERY GMBH
Inventors:
Torsten Grothe, Ernst Roemer, Philipp Wabnitz
Abstract: The present invention provides a method for producing ?-3 polyunsaturated fatty acids by culturing specific myxobacterial stains and myxobacterial strains suitable for said method.
Type:
Application
Filed:
December 1, 2009
Publication date:
November 10, 2011
Applicant:
INTERMED DISCOVERY GMBH
Inventors:
Ernst Roemer, Rolf Müller, Ronald O. Garcia, Mark Stadler, Dominik Pistorius, Alexander Brachmann
Abstract: The invention relates to the use, or methods (especially with regard to animals, especially human, that are in need of such treatment) comprising the use, of an extract and/or one or more natural compounds from plants or parts of plants, respectively, from a genus selected from the group consisting of Schisandra, Illicium, Kadsura, Steganotaenia and Magnolia, alone or as supplement, as active ingredient in the regulation of body weight and/or fat loss and/or for the management of obesity, either in humans or in animals, to the use of said extract and/or natural compound(s) or mixtures in the manufacture of a pharmaceutical or nutraceutical formulation for the regulation of body weight and/or fat loss and/or for the management of obesity either in humans or in animals. The above extract and/or compound(s) can further be used to reduce one or more adverse metabolic parameters in a subject.
Type:
Application
Filed:
July 29, 2008
Publication date:
September 1, 2011
Applicant:
INTERMED DISCOVERY GMBH
Inventors:
Torsten Grothe, Ernst Roemer, Thomas Henkel
Abstract: Compounds obtainable from plants, e.g. of the genus Eucalyptus, or from microorganisms are shown to be useful as CNS activity modulators useful e.g. in the treatment of depression, for lifting mood and/or for increasing behavioural initiative and the like. This use and related aspects form embodiments of the invention. Also compounds as such are presented. The compounds useful are acylphloroglucine derivatives of the formula I, wherein the substituents are as defined in the description.
Abstract: The present invention relates to substituted heterocycles, processes for their preparation, and their use in medicaments, especially for the treatment of inflammatory disease, i.e. asthma, or cancer.
Type:
Application
Filed:
January 8, 2009
Publication date:
January 20, 2011
Applicant:
INTERMED DISCOVERY GMBH
Inventors:
Marc STADLER, Stephan Seip, Hartwig Müller, Anke Mayer-Bartschmid, Michael-Alexander Brüning, Jordi Benet-Buchholz, Hiroko Togame, Reiko Dodo, Peter Reinemer, Kevin Bacon, Kinji Fuchikami, Satoko Matsukawa, Klaus Urbahns