Patents Assigned to INTERMED DISCOVERY GMBH
-
Publication number: 20130338219Abstract: The invention relates to compositions and methods (with regard to animals and humans) for utilizing an extract and/or one or more natural spiro triterpenoids and derivatives thereof alone or as a supplement. Certain materials utilized are from the blazeispirol family, obtainable from Agaricus species. Treatments include the prophylactic and/or therapeutic treatment of a disease, disorder or condition that responds to the modulation of Liver X receptor, as well as corresponding methods of treatment, the manufacture of a pharmaceutical and nutraceutical formulation for said treatment. The invention also relates to the use of the extract and compound(s) in the treatment or in the preparation of a medicament (e.g. a nutraceutical) for the prophylactic and/or therapeutic treatments, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations described herein which are useful in prophylactic and therapeutic treatments. They can also be used for non-therapeutic, e.g.Type: ApplicationFiled: December 8, 2011Publication date: December 19, 2013Applicant: Intermed Discovery GMBHInventors: Torsten Grothe, Marc Stadler, Bärbel Köpcke, Ernst Roemer, Jens Bitzer, Philipp Wabnitz, Thomas Küper
-
Publication number: 20130143959Abstract: The invention relates to an extract and/or one or more natural compounds from plants or parts of plants, respectively, from a genus selected from Schisandra, Illicium, Kadsura, Steganotaenia or Magnolia, for the regulation of body weight, fat loss, and/or management of obesity, in humans or in animals, methods and uses of the same and to the use of the same or mixtures in the manufacture of a pharmaceutical or nutraceutical formulation. The above can further be used to reduce one or more adverse metabolic parameters in a subject. The invention relates also to said extract and/or compound(s) in the treatment or in the preparation of a medicament for treatment of obesity, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations comprising said extract and/or natural compound(s), which are useful in the regulation of body weight and/or fat loss and/or for the management of obesity.Type: ApplicationFiled: November 19, 2012Publication date: June 6, 2013Applicant: INTERMED DISCOVERY GMBHInventor: INTERMED DISCOVERY GMBH
-
Publication number: 20130023586Abstract: A compound of the formula I, wherein the symbols are as defined in the remaining specification, or a mixture of two or more compounds of the formula I, for use as active ingredient in the therapeutic—including prophylactic—treatment of a warm-blooded animal for the regulation of body weight (preferred) and/or fat loss (preferred) and/or for the management of obesity and/or for improving the total cholesterol HDL/LDL ratio; where the compound(s) of the formula I may be present in free form, in the form of a pharmaceutically and/or nutraceutically acceptable salt, in the form of tautomers, in the form of esters and/or in the form of solvates, as well as related invention embodiments.Type: ApplicationFiled: January 13, 2011Publication date: January 24, 2013Applicant: INTERMED DISCOVERY GMBHInventors: Torsten Grothe, Ernst Roemer, Philipp Wabnitz
-
Publication number: 20120058172Abstract: Compounds obtainable from plants, e.g. of the genus Eucalyptus, or from microorganisms are shown to be useful as CNS activity modulators useful e.g. in the treatment of depression, for lifting mood and/or for increasing behavioural initiative and the like. This use and related aspects form embodiments of the invention. Also compounds as such are presented. The compounds useful are acylphloroglucine derivatives of the formula I, wherein the substituents are as defined in the description.Type: ApplicationFiled: November 11, 2011Publication date: March 8, 2012Applicant: Intermed Discovery GmbHInventors: Ernst Roemer, Torsten Grothe
-
Publication number: 20120040956Abstract: The invention relates to cyclopentabenzofuran derivatives for the treatment and/or prophylaxis of angiogenesis-related disorders.Type: ApplicationFiled: June 3, 2011Publication date: February 16, 2012Applicant: INTERMED DISCOVERY GMBHInventors: Philipp WABNITZ, Matthias Gehling, Thomas Henkel, M. Lienhard Schmitz
-
Publication number: 20110275846Abstract: The present invention provides a method for producing ?-3 polyunsaturated fatty acids by culturing specific myxobacterial stains and myxobacterial strains suitable for said method.Type: ApplicationFiled: December 1, 2009Publication date: November 10, 2011Applicant: INTERMED DISCOVERY GMBHInventors: Ernst Roemer, Rolf Müller, Ronald O. Garcia, Mark Stadler, Dominik Pistorius, Alexander Brachmann
-
Publication number: 20110213026Abstract: The invention relates to the use, or methods (especially with regard to animals, especially human, that are in need of such treatment) comprising the use, of an extract and/or one or more natural compounds from plants or parts of plants, respectively, from a genus selected from the group consisting of Schisandra, Illicium, Kadsura, Steganotaenia and Magnolia, alone or as supplement, as active ingredient in the regulation of body weight and/or fat loss and/or for the management of obesity, either in humans or in animals, to the use of said extract and/or natural compound(s) or mixtures in the manufacture of a pharmaceutical or nutraceutical formulation for the regulation of body weight and/or fat loss and/or for the management of obesity either in humans or in animals. The above extract and/or compound(s) can further be used to reduce one or more adverse metabolic parameters in a subject.Type: ApplicationFiled: July 29, 2008Publication date: September 1, 2011Applicant: INTERMED DISCOVERY GMBHInventors: Torsten Grothe, Ernst Roemer, Thomas Henkel
-
Publication number: 20110021613Abstract: Compounds obtainable from plants, e.g. of the genus Eucalyptus, or from microorganisms are shown to be useful as CNS activity modulators useful e.g. in the treatment of depression, for lifting mood and/or for increasing behavioural initiative and the like. This use and related aspects form embodiments of the invention. Also compounds as such are presented. The compounds useful are acylphloroglucine derivatives of the formula I, wherein the substituents are as defined in the description.Type: ApplicationFiled: December 11, 2007Publication date: January 27, 2011Applicant: INTERMED DISCOVERY GMBHInventors: Ernst Roemer, Torsten Grothe
-
Publication number: 20110015248Abstract: The present invention relates to substituted heterocycles, processes for their preparation, and their use in medicaments, especially for the treatment of inflammatory disease, i.e. asthma, or cancer.Type: ApplicationFiled: January 8, 2009Publication date: January 20, 2011Applicant: INTERMED DISCOVERY GMBHInventors: Marc STADLER, Stephan Seip, Hartwig Müller, Anke Mayer-Bartschmid, Michael-Alexander Brüning, Jordi Benet-Buchholz, Hiroko Togame, Reiko Dodo, Peter Reinemer, Kevin Bacon, Kinji Fuchikami, Satoko Matsukawa, Klaus Urbahns