Patents Assigned to INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY (ICGEB)
  • Proteins with cardioprotective activity
    Patent number: 12121594
    Abstract: A protein selected from the group consisting of Chrdl1, Fam3c, Fam3b and a fragment thereof, or a polynucleotide encoding therefor, for use in treating or reducing the risk of heart disease.
    Type: Grant
    Filed: August 16, 2022
    Date of Patent: October 22, 2024
    Assignee: International Centre for Genetic Engineering and Biotechnology (ICGEB)
    Inventors: Mauro Giacca, Giulia Ruozi, Francesca Bortolotti
  • EMID2 PROTEIN AS ANTI-CANCER TREATMENT
    Publication number: 20230241183
    Abstract: The present invention refers to the EMID2 protein or its EMI domain or a nucleic acid coding thereof for use for the treatment of a tumor or for the treatment or prevention of metastasis. Compositions, vectors and formulations for the administration of EMID2 or its EMI domain or a nucleic acid coding thereof for the above mentioned uses are also within the scope of the invention.
    Type: Application
    Filed: May 11, 2021
    Publication date: August 3, 2023
    Applicants: INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY - ICGEB, UNIVERSITA' DEGLI STUDI DI TRIESTE
    Inventors: Serena ZACCHIGNA, Mauro GIACCA, Ambra CAPPELLETTO
  • Antimalarial compounds, process for preparation and their use for drug resistant malaria
    Patent number: 11365202
    Abstract: The present invention provides a new artemisinin-dipeptidyl vinyl based compound of Formula (I) or a pharmaceutically acceptable salt thereof and a process for the preparation thereof. The present invention further also provides a pharmaceutical composition comprising compounds of Formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or excipient to treat malaria.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: June 21, 2022
    Assignees: Council of Scientific and Industrial Research, International Centre for Genetic Engineering and Biotechnology (ICGEB)
    Inventors: Asish Kumar Bhattacharya, Eswar Kumar Aratikatla, Pawan Malhotra, Asif Mohmmed
  • Modified bacteria for the production of bioalcohol
    Patent number: 9914943
    Abstract: The present invention provides a modified bacterial strain capable of fermenting both hexose and pentose sugars for production of bioalcohol wherein a promoter of pyruvate dehydrogenase operon (PDH) is replaced with a promoter of a gene that is expressed under anaerobic conditions. The present invention further provides a method of obtaining modified bacterial strain capable of fermenting both hexose and pentose sugar for production of bioalcohol. The present invention also provides a method of fermenting lignocellulosic biomass having hexose and pentose sugar using the modified bacteria for production of biomass.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: March 13, 2018
    Assignees: DEPARTMENT OF BIOTECHNOLOGY MINISTRY OF SCIENCE & TECHNOLOGY, INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY (ICGEB)
    Inventors: Syed Shams Yazdani, Neha Munjal, Anu Jose Mattam
  • Modified bacteria for the production of bioalcohol
    Patent number: 9631206
    Abstract: The present invention provides a modified bacterial strain capable of fermenting both hexose and pentose sugars for production of bioalcohol wherein a promoter of pyruvate dehydrogenase operon (PDH) is replaced with a promoter of a gene that is expressed under anaerobic conditions. The present invention further provides a method of obtaining modified bacterial strain capable of fermenting both hexose and pentose sugar for production of bioalcohol. The present invention also provides a method of fermenting lignocellulosic biomass having hexose and pentose sugar using the modified bacteria for production of biomass.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: April 25, 2017
    Assignees: DEPARTMENT OF BIOTECHNOLOGY MINISTRY OF SCIENCE & TECHNOLOGY, INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY (ICGEB)
    Inventors: Syed Shams Yazdani, Neha Munjal, Anu Jose Mattam