Abstract: Compositions and methods are provided for genome modification of a target sequence in the genome of a plant or plant cell. The methods and compositions employ a guide RNA/Cas endonuclease system to provide an effective system for modifying or altering target sites within the genome of a plant, plant cell or seed. Also provided are compositions and methods employing a guide polynucleotide/Cas endonuclease system for genome modification of a nucleotide sequence in the genome of a cell or organism, for gene editing, and/or for inserting or deleting a polynucleotide of interest into or from the genome of a cell or organism. Once a genomic target site is identified, a variety of methods can be employed to further modify the target sites such that they contain a variety of polynucleotides of interest. Breeding methods and methods for selecting plants utilizing a two component RNA guide and Cas endonuclease system are also disclosed.

Abstract: Soybean plants and soybean seeds comprise increased amounts of essential amino acids such as methionine, tryptophan or lysine. Soybean plants, soybean seeds and soy protein compositions comprising a modified glycinin protein, modified amounts of glycinin and beta-conglycinin, or both have increases in one or more essential amino acids. Protein compositions having increased essential amino acids can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions having increased amounts of essential amino acids are disclosed.

Abstract: Disclosed is a process for the synthesis of fluorinated olefins, and in particularly preferred embodiments tetrafluorinated olefins having F on an unsaturated, non-terminal carbon, such as 2,3,3,3-tetrafluoropropene. The preferred processes of the present invention in accordance with one embodiment generally comprise: (a) reacting a compound of formula (I) X1X2??(I) with a compound of formula (II) CX1X2X3CX1?CX1X2??(II) to produce a reaction product comprising a compound of formula (III) CF3CHX1CH2X2??(III), and (b) exposing said compound of formula (III) to reaction conditions effective to convert said compound of formula (III) to a compound of formula (IV) CF3CZ?CH2??(IV) wherein X1, X2, and X3 are each independently selected from the group consisting of hydrogen, chlorine, bromine, fluorine and iodine, provided that X1 and X2 in formula (I) are not both hydrogen and Z is Cl, I, Br, or F.

Abstract: A method of cleaning a complex powder transfer system including providing a powder transfer system having a washing fluid source, a spray device valve in fluid communication with the washing fluid source, a backflush valve in fluid communication with the washing fluid source, a receiving device having an upper chamber, a lower chamber, and a membrane filter disposed between the upper and lower chambers. The method includes opening the backflush valve to initiate a backflush cycle, running the backflush cycle to wash the upper chamber with a fluid, and closing the backflush valve after the backflush cycle completes. The method includes opening the spray device valve to initiate a spray device cycle, running the spray device cycle to wash the lower chamber with fluid, and closing the spray device valve after the spray device cycle completes. The method includes opening a pressure valve to provide PCA to the receiving container.

Abstract: Systems and methods for routing trade orders based on exchange latency are disclosed. An example method includes measuring a first latency associated with a first exchange based on a processing time of a first trade order; and routing a second trade order from a trading device to one of the first and a second exchange based on the first latency.

Abstract: A system and method is provided for proactive process intervention in manufacturing creped products via a chemical feed stage and a Yankee dryer stage. The method includes generating signals from a plurality of online sensors, corresponding to directly measured variables for respective process components such as, e.g., pH, conductivity, and Yankee blade vibration. Models are developed including retrievable information relating combinations of certain directly measured variables to respective quality characteristics of the creped product. The method further includes indirectly determining quality characteristics (e.g., softness, bulk) for the creped product, substantially in real time, based on, e.g., signals corresponding to directly measured variables, and optionally a predicted natural coating potential.

Abstract: Methods and system for detecting tampering of a meter. A continuous stream of raw sensor values can be received from one or more meters among a group of meters. In response to receiving the continuous stream of raw sensor values from the meter(s), a model of normal sensor values can be automatically constructed for each meter among the group of meters based on the raw sensor values obtained from the meter(s) and based on data obtained through an ongoing development of the meter(s) or through automated machine learning by the meter(s). The model of normal sensor values can be used to detect abnormal conditions with respect to the meter(s). The abnormal conditions detected with respect to the meter(s) are potentially indicative of a removal of the meter(s) or of an attempt to physically tamper with the meter(s).

Abstract: A novel maize variety designated 1PAEZ42 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety 1PAEZ42 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 1PAEZ42 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety 1PAEZ42 or a locus conversion of 1PAEZ42 with another maize variety.

Abstract: A system for remote diagnostic analysis of a heating, ventilation and air condition (HVAC) system is provided. The system includes a thermostat in operable communication with at least one peripheral component of the HVAC system and configured to receive information relating to the at least one peripheral component, and a server in operable communication with the thermostat for receiving and analyzing the information. The server causes the at least one peripheral component to conduct a diagnostic test and analyzes the test result to perform a root cause analysis of a system malfunction.

Abstract: A gas detection apparatus and method for measuring humidity using an electrochemical gas sensor. The gas detection apparatus comprises an electrolyte-based electrochemical gas sensor and a controller configured to measure the average humidity value within an ambient environment over a period of time. The average ambient humidity value over the period of time is determined based on the average rate of change over the period of time of the electrolyte concentration within the electrolyte gas sensor of the gas detection apparatus over the period and the average temperature in the ambient environment over the period of time. The gas sensing apparatus may be configured to communicate the average ambient humidity value within the ambient environment to a second electrochemical gas sensor or a second gas detection apparatus within the same ambient environment.

Abstract: A wrist-wearable electronic device comprising first and second light emitting elements, a sensor, and a processor. The processor is configured to transmit a first command to the first light emitting element in response to the wrist-wearable device reaching a forward position relative to a user based on data received from the sensor and transmit a second command to the second light emitting element in response to the wrist-wearable device reaching a rearward position relative to the user based on the data from the sensor.

Abstract: A pharmaceutically acceptable insulin premix formulation contains about 0.1-10.0 Unit/mL of insulin for intravenous administration and preferably further contains a tonicity adjuster. The methods for making and using such formulation are also provided. The pharmaceutically acceptable insulin premix formulation may be aseptically filled into a flexible container assembly to form a pharmaceutical insulin premix product. The insulin premix product can be a sterile and ready-to-use aqueous solution for glycemic control in an individual with metabolic disorders through intravenous infusion. The insulin premix product is unexpectedly stable when freshly prepared and also during its shelf-life of storage at refrigeration temperatures of 2° C. to 5° C. for 24 months followed by additional 30 days at room temperatures of 23° C. to 27° C., even without any added preservative, any added zinc, any added surfactant or any other added stabilizing excipient.

Abstract: A process for aligning a laser in a gear inspection system is disclosed. The method comprises fixing a gear for inspection within a gear inspection system and emitting a first signal from a laser to a point of interest of the gear. A reflection of the first signal is received as the first signal reflects off the point of interest of the gear. Based on the reflection of the first signal, an orientation of the laser is adjusted. Subsequently, a second signal is emitted from the laser to the point of interest of the gear, and a reflection of the second signal is received as the second signal reflects off the point of interest of the gear. Values corresponding to the orientation of the laser are stored based on the reflection of the second signal.

Abstract: An environmental control system includes an air conditioning subsystem and a contaminant removal subsystem downstream of the environment to be conditioned. The contaminant removal subsystem includes: a first gas-liquid contactor-separator; a second gas-liquid contactor-separator; and a dehumidifier disposed either upstream of the first gas-liquid contactor-separator or downstream of the second gas-liquid contactor-separator.

Abstract: Autoland systems and processes for landing an aircraft without pilot intervention are described. In implementations, the autoland system includes a memory operable to store one or more modules and at least one processor coupled to the memory. The processor is operable to execute the one or more modules to identify a plurality of potential destinations for an aircraft. The processor can also calculate a merit for each potential destination identified, select a destination based upon the merit; receive terrain data and/or obstacle data, the including terrain characteristic(s) and/or obstacle characteristic(s); and create a route from a current position of the aircraft to an approach fix associated with the destination, the route accounting for the terrain characteristic(s) and/or obstacle characteristic(s). The processor can also cause the aircraft to traverse the route, and cause the aircraft to land at the destination without requiring pilot intervention.

Abstract: A novel maize variety designated 1PNZQ23 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety 1PNZQ23 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 1PNZQ23 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety 1PNZQ23 or a locus conversion of 1PNZQ23 with another maize variety.

Abstract: A system comprises a particle sensor unit in communication with a processor. The sensor unit comprises a source that transmits light into an interrogation region; receive optics that collect scattered light from particles in the interrogation region; and an optical detector that receives the collected light from the receive optics. The detector comprises a sample area including one or more sampling pixels, and an edge region including one or more edge pixels. The processor analyzes intensity data from the detector by a method comprising: combining all intensity data from the sampling pixels; adding the combined intensity data to a data set; determining whether to accept overlap intensity data that corresponds to an overlap between the sampling pixels and the edge pixels; adding the overlap intensity data to the data set if accepted; discarding the overlap intensity data if not accepted; and discarding all non-overlapping intensity data from the edge pixels.

Abstract: A method includes accessing, from a data store, at least one predefined data classification for asset data associated with multiple assets in an industrial process control system, wherein the at least one predefined data classification is associated with one or more first policies, wherein the data store stores a plurality of data classifications for asset data. The method also includes receiving user input of a customization to the at least one predefined data classification to generate at least one customized data classification associated with one or more second policies. The method further includes storing the at least one customized data classification in the data store. The method also includes collecting asset data from at least one of the multiple assets. The method further includes processing the collected asset data according to the one or more second policies associated with the at least one customized data classification.

Abstract: The present invention provides a rear projection simulator system with a free-form fold mirror. The system includes a high definition projector and a curved screen. The free-form fold mirror is interposed between the projector and the screen. The free-form fold mirror includes one or more non-planar (e.g., curved) portions to eliminate or reduce loss of resolution of the projected image near the edges or boundaries of the image.

Abstract: Devices, methods, and systems for determining the cause of a fault in a heating, ventilation, and air conditioning (HVAC) system are described herein. One device includes a memory, and a processor configured to execute executable instructions stored in the memory to receive operational data associated with an HVAC system, receive control logic associated with a controller of the HVAC system, determine a cause of a fault occurring in the HVAC system based, at least in part, on the operational data associated with the HVAC system and the control logic of the controller of the HVAC system, and provide the cause of the fault occurring in the HVAC system to a user.