Patents Assigned to INTERNATIONAL PARK OF CREATIVITY
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Patent number: 10501815Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.Type: GrantFiled: April 2, 2018Date of Patent: December 10, 2019Assignee: International Park of CreativityInventor: Raul Cuero Rengifo
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Publication number: 20180223379Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.Type: ApplicationFiled: April 2, 2018Publication date: August 9, 2018Applicant: INTERNATIONAL PARK OF CREATIVITYInventor: Raul CUERO RENGIFO
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Patent number: 10011841Abstract: Described herein are methods and devices for ligating nucleic acids or nucleic acid fragments as well as methods for transforming or transfecting cells with exogenous DNA. The methods and devices generally involve exposing the nucleic acids, nucleic acid fragments, and/or cells to an electromagnetic field, for example, a mini-current electromagnetic field, while performing the steps of ligation or transformation. The methods and devices provide numerous advantages over conventional ligation and transformation techniques and systems such as reduced reaction times, no heating requirements, and reduced amounts of reagents. Finally, as shown in the examples below, the methods and devices described herein are more effective compared to conventional ligation and transformation techniques and systems.Type: GrantFiled: July 31, 2014Date of Patent: July 3, 2018Assignee: International Park of CreativityInventors: Raul Cuero Rengifo, Natalia Gutierrez Calle, Mariana Sanchez Londono
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Patent number: 9932644Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.Type: GrantFiled: April 27, 2017Date of Patent: April 3, 2018Assignee: International Park of CreativityInventors: Raul Cuero Rengifo, Juliana Maria Navia
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Patent number: 9890201Abstract: Described herein are devices and methods for simultaneously expressing amyloid precursor protein and TonB protein. For example, the biological devices and methods described herein increase the production of these two proteins while also reducing the cost, making these proteins more widely accessible for medical research purposes, including for the development of diagnostic tests for Alzheimer's disease. The amyloid precursor protein and TonB protein produced by the devices and methods described herein, as well as the devices themselves, can be used in experiments designed to model the interactions between metals and ?-amyloid that are characteristic of Alzheimer's disease.Type: GrantFiled: August 4, 2014Date of Patent: February 13, 2018Assignee: International Park of CreativityInventors: Raul Cuero Rengifo, Diana Marcela Vasquez Forero
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Patent number: 9868811Abstract: Described herein are polyurethane compositions based on natural materials, as well as methods for making and using the compositions. Also described herein are biofoams made from the polyurethane compositions. The biofoams described herein are resistant to degradation by acid and heat and are able to recover their original shapes after the application of pressure.Type: GrantFiled: August 4, 2014Date of Patent: January 16, 2018Assignee: INTERNATIONAL PARK OF CREATIVITYInventors: Raul Cuero Rengifo, Gabriela Melo Rodriguez
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Patent number: 9828609Abstract: Described herein are devices and methods for enhancing the physiological properties of plants. For example, the devices and methods described herein increase the production of lycopene, which has industrial and economic value. The lycopene produced by the devices and methods does not require the ultra purification that is common in conventional or commercial methods. The devices and methods described herein also enhance the growth rate of plants.Type: GrantFiled: March 11, 2014Date of Patent: November 28, 2017Assignee: International Park of CreativityInventor: Raul Cuero Rengifo
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Publication number: 20170240979Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.Type: ApplicationFiled: April 27, 2017Publication date: August 24, 2017Applicant: INTERNATIONAL PARK OF CREATIVITYInventors: Raul CUERO RENGIFO, Juliana Maria Navia
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Patent number: 9683266Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.Type: GrantFiled: April 19, 2012Date of Patent: June 20, 2017Assignee: INTERNATIONAL PARK OF CREATIVITYInventors: Raul Cuero Rengifo, Juliana Maria Navia
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Publication number: 20160168214Abstract: Described herein are devices and methods for simultaneously expressing amyloid precursor protein and TonB protein. For example, the biological devices and methods described herein increase the production of these two proteins while also reducing the cost, making these proteins more widely accessible for medical research purposes, including for the development of diagnostic tests for Alzheimer's disease. The amyloid precursor protein and TonB protein produced by the devices and methods described herein, as well as the devices themselves, can be used in experiments designed to model the interactions between metals and ?-amyloid that are characteristic of Alzheimer's disease.Type: ApplicationFiled: August 4, 2014Publication date: June 16, 2016Applicant: INTERNATIONAL PARK OF CREATIVITYInventors: Raul Cuero RENGIFO, Diana Marcela VASQUEZ FORERO
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Publication number: 20160168311Abstract: Described herein are polyurethane compositions based on natural materials, as well as methods for making and using the compositions. Also described herein are biofoams made from the polyurethane compositions. The biofoams described herein are resistant to degradation by acid and heat and are able to recover their original shapes after the application of pressure.Type: ApplicationFiled: August 4, 2014Publication date: June 16, 2016Applicant: INTERNATIONAL PARK OF CREATIVITYInventors: Raul CUERO RENGIFO, Gabriela MELO RODRIGUEZ
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Publication number: 20160109339Abstract: Described herein are compositions and methods for effectively removing from soil samples. By isolating the oil from the soil sample, it is possible to accurately evaluate the different properties of the oil in the sample.Type: ApplicationFiled: May 21, 2014Publication date: April 21, 2016Applicant: INTERNATIONAL PARK OF CREATIVITYInventors: Raul CUERO RENGIFO, Jhon Henry TRUJILLO MONTENEGRO, Jennifer Melissa RUSSI CASTILLO, Mauricio CASTILLO PALACIOS
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Publication number: 20160017362Abstract: Described herein are devices and methods for enhancing the physiological properties of plants. For example, the devices and methods described herein increase the production of lycopene, which has industrial and economic value. The lycopene produced by the devices and methods does not require the ultra purification that is common in conventional or commercial methods. The devices and methods described herein also enhance the growth rate of plants.Type: ApplicationFiled: March 11, 2014Publication date: January 21, 2016Applicant: INTERNATIONAL PARK OF CREATIVITYInventors: Raul CUERO RENGIFO, Maria ALEJANDRA CABRERA DELGADO
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Patent number: 9044729Abstract: Methods and devices for amplifying nucleic acids generally involve exposing the nucleic acid to an electromagnetic field, for example a mini-current magnetic field, while performing the steps of PCR. The PCR methods and devices provide numerous advantages over conventional PCR techniques and systems such as reduced reaction times, no heating requirements, and reduced amounts of reagents (e.g., optional use polymerases and primers). Additionally, the PCR methods and devices require significantly shorter reaction times (e.g., less than one hour) compared to conventional PCR techniques and systems (minimum 2 hours). Finally, as shown in the Examples, the PCR methods and devices amplify significantly more DNA compared to conventional PCR techniques and systems. Accordingly, the PCR methods and devices provide a more efficient and cost-effective way to perform PCR when compared to conventional PCR techniques and systems.Type: GrantFiled: March 15, 2013Date of Patent: June 2, 2015Assignee: International Park of CreativityInventors: Raul Cuero Rengifo, Mario Antonio Franco Jimenez, Natalia Gutierrez Calle, Mariana Sanchez Londono
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Publication number: 20140287425Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.Type: ApplicationFiled: April 19, 2012Publication date: September 25, 2014Applicant: INTERNATIONAL PARK OF CREATIVITYInventors: Raul Cuero Rengifo, Juliana Maria Navia
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Publication number: 20140030764Abstract: Methods and devices for amplifying nucleic acids generally involve exposing the nucleic acid to an electromagnetic field, for example a mini-current magnetic field, while performing the steps of PCR. The PCR methods and devices provide numerous advantages over conventional PCR techniques and systems such as reduced reaction times, no heating requirements, and reduced amounts of reagents (e.g., optional use polymerases and primers). Additionally, the PCR methods and devices require significantly shorter reaction times (e.g., less than one hour) compared to conventional PCR techniques and systems (minimum 2 hours). Finally, as shown in the Examples, the PCR methods and devices amplify significantly more DNA compared to conventional PCR techniques and systems. Accordingly, the PCR methods and devices provide a more efficient and cost-effective way to perform PCR when compared to conventional PCR techniques and systems.Type: ApplicationFiled: March 15, 2013Publication date: January 30, 2014Applicant: INTERNATIONAL PARK OF CREATIVITYInventors: Raul Cuero RENGIFO, Mario Antonio FRANCO JIMENEZ, Natalia GUTIERREZ CALLE, Mariana SANCHEZ LONDONO