Abstract: The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Type:
Grant
Filed:
October 24, 2008
Date of Patent:
May 31, 2011
Assignee:
Intersect ENT, Inc.
Inventors:
Donald J. Eaton, Mary Lynn Moran, Rodney A. Brenneman
Abstract: The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Type:
Grant
Filed:
October 24, 2008
Date of Patent:
May 31, 2011
Assignee:
Intersect, ENT, Inc.
Inventors:
Donald J. Eaton, Mary Lynn Moran, Rodney A. Brenneman
Abstract: The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Type:
Grant
Filed:
September 15, 2010
Date of Patent:
May 31, 2011
Assignee:
Intersect ENT, Inc.
Inventors:
Donald J. Eaton, Mary L. Moran, Rodney A. Brenneman
Abstract: The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Type:
Grant
Filed:
September 15, 2010
Date of Patent:
May 31, 2011
Assignee:
Intersect ENT, Inc.
Inventors:
Donald J. Eaton, Mary L. Moran, Rodney A. Brenneman
Abstract: The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Type:
Grant
Filed:
September 15, 2010
Date of Patent:
May 31, 2011
Assignee:
Intersect ENT, Inc.
Inventors:
Donald J. Eaton, Mary L. Moran, Rodney A. Brenneman
Abstract: The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Type:
Grant
Filed:
September 15, 2010
Date of Patent:
May 31, 2011
Assignee:
Intersect ENT, Inc.
Inventors:
Donald J. Eaton, Mary L. Moran, Rodney A. Brenneman
Abstract: The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Type:
Grant
Filed:
April 7, 2009
Date of Patent:
May 11, 2010
Assignee:
Intersect ENT, Inc.
Inventors:
Donald J. Eaton, Mary L. Moran, Rodney Brenneman
Abstract: The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Type:
Grant
Filed:
April 7, 2009
Date of Patent:
April 6, 2010
Assignee:
Intersect ENT, Inc.
Inventors:
Donald J. Eaton, Mary L. Moran, Rodney Brenneman