Patents Assigned to InterVet, Inc.
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Patent number: 11825814Abstract: A system for external fish parasites monitoring in aquaculture, the system comprising: —a camera (52) suitable to be submerged in a sea pen suitable for containing comprising fish, the camera being arranged for capturing images of the fish; and—an electronic image processing system (86) configured for identifying external fish parasites on the fish by analyzing the captured images, wherein: —a ranging detector (54) configured for detecting the presence of fish and measuring a distance from the detector to the fish is mounted adjacent to the camera (52); and—an electronic control system (12) is arranged to control a focus of the camera (52) on the basis of the measured distance and to trigger the camera (52) when a fish has been detected within a predetermined distance range.Type: GrantFiled: December 19, 2018Date of Patent: November 28, 2023Assignee: INTERVET INC.Inventors: Russel Howe, Zachary Lizer, James Wallace Sarrett, Peter Jon Abrahamson, Jascha Tucker Little
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Publication number: 20230363359Abstract: The present invention pertains to a method for automatic sea lice monitoring in fish aquaculture, the method comprising submerging a camera (4) in a sea pen (300) comprising fish, using the camera to make an image of at least one of said fish, analysing the image to differentiate between individual sea lice present on the fish and the fish itself and assessing the number of sea lice present on the fish, wherein the camera is attached to a device (1, 10, 100) for guiding the salmon along an imaging track (5), the camera being directed to the track.Type: ApplicationFiled: April 19, 2023Publication date: November 16, 2023Applicant: Intervet Inc.Inventors: Peter Jans, Evert Gijtenbeek
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Publication number: 20230355741Abstract: The present invention provides new vaccines for felines and ferrets to aid in reducing shedding of severe acute respiratory syndrome coronavirus 2 by infected felines or ferrets. Methods of making and using the vaccines alone or in combinations with other protective agents are also provided.Type: ApplicationFiled: May 10, 2021Publication date: November 9, 2023Applicant: Intervet Inc.Inventors: Mark A. Mogler, Ian Tarpey
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Publication number: 20230338500Abstract: The invention pertains to a combination of a first vaccine comprising anon-replicating immunogen of porcine circovirus type 2 (PCV-2) and a non-replicating immunogen of Mycoplasma hyopneumoniae, and a second vaccine comprising a live attenuated porcine reproductive and respiratory syndrome (PRRS) virus, for use in prophylactically treating a pig against an infection with PCV-2, an infection with Mycoplasma hyopneumoniae and an infection with PRRS virus, by associated separate injection of the first vaccine and the second vaccine into a tissue of the pig at a first and a second injection site respectively, wherein the first and second injection sites are at most 5 cm apart from each other.Type: ApplicationFiled: April 19, 2021Publication date: October 26, 2023Applicant: Intervet Inc.Inventors: Maarten Hendrik Witvliet, Jacquelyn Horsington
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Publication number: 20230340032Abstract: The present invention relates to a novel equine parvovirus associated with respiratory distress and recurrent laryngeal neuropathy in equine, to nucleic acid fragments and proteins of the virus and to vaccines based upon the virus, proteins and nucleic acid fragments. The invention also relates to a diagnostic test for the detection of the vims or antibodies against the virus.Type: ApplicationFiled: February 22, 2021Publication date: October 26, 2023Applicant: Intervet Inc.Inventors: Ad De Groof, Cornelia Maria Van Der Hoek, Martin Deijs, Cornelis Maanen Van
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Publication number: 20230320981Abstract: A solid oral pharmaceutical composition for delivery of a pharmaceutically acceptable active ingredient to an animal where the composition comprises an isoxazoline compound, a solvent and an excipient, a process for the manufacture of such solid oral pharmaceutical composition and a method of controlling a parasite infection administering such solid oral pharmaceutical composition.Type: ApplicationFiled: June 15, 2023Publication date: October 12, 2023Applicant: Intervet Inc.Inventors: Keith Freehauf, Niki Waldron, Jürgen Lutz, Frank Guerino
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Publication number: 20230310386Abstract: The present invention relates to injectable compositions comprising the combination of an isoxazoline compound as well as a physiologically active macrocyclic lactone such as moxidectin.Type: ApplicationFiled: May 19, 2021Publication date: October 5, 2023Applicant: Intervet Inc.Inventors: Brenda L. Valle Colon, Keith Freehauf, Christopher D. Kulczar, Frank Guerino
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Publication number: 20230295289Abstract: The present invention provides compositions for treating canine atopic dermatitis that comprise a fusion protein that binds canine IL-22, a caninized anti-pruritic antibody, and a caninized anti-inflammatory antibody. The present invention further provides compositions that comprise a bispecific binding partners that comprises that fusion protein and a caninized anti-pruritic antibody or a caninized anti-inflammatory antibody, or alternatively, a bispecific antibody comprising a caninized anti-pruritic antibody and a caninized anti-inflammatory antibody, which in addition comprises a fusion protein that binds canine IL-22.Type: ApplicationFiled: December 18, 2020Publication date: September 21, 2023Applicant: Intervet Inc.Inventors: Mohamad Morsey, Yuanzheng Zhang, Anasuya Saha
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Publication number: 20230277649Abstract: The present invention relates to an immunogenic composition comprising first and second RNA replicon particles. The first RNA replicon particle comprises a nucleic acid construct comprising first and second nucleic acid sequences encoding first and second hemagglutinin (HA) antigens of a Swine influenza A virus (IAV-S). The first HA antigen is a of the A/swine/Gent/1/1984-like H3N2 (Gent/84) lineage, and the second HA antigen is of the A(H1N1)pdm09 (pdm09) lineage. The second RNA replicon particle comprises a nucleic acid construct comprising third and fourth nucleic acid sequences encoding third and fourth HA antigens of S. The third HA antigen is of the A/swine/Scotland/410440/1994-like H1huN2 (Scot/94) lineage, and the fourth HA antigen is of the Eurasian avian-like H1avN1 (EA) lineage. In other embodiments, the present invention relates to a vaccine, which may be used against influenza A virus infection, and comprising the immunogenic composition.Type: ApplicationFiled: June 18, 2021Publication date: September 7, 2023Applicant: Intervet Inc.Inventors: Mark A. Mogler, Basav Hangalapura Nagaraj
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Patent number: 11741731Abstract: A parasite analysis system includes a pressure vessel configured to store a biological sample, an imaging cell connected to the pressure vessel, and a waste depository connected to the imaging cell. An input valve controls whether biological sample can flow from the pressure vessel into the imaging cell and an output valve controls whether biological sample can flow from the imaging cell into the waste depository. The parasite analysis system also includes a camera that captures a chronological set of images of a portion of the biological sample in the imaging cell and an image analysis system that analyzes the chronological set of images to generate an estimate of a number of parasites in the portion of the biological sample. Estimates for multiple portions of the biological sample may be generated and sampling techniques used to estimate the number of parasites in the entire biological sample.Type: GrantFiled: July 18, 2022Date of Patent: August 29, 2023Assignee: Intervet Inc.Inventors: Pavel Vácha, Petr Jankuj, Richard Josef Marhoefer, Václav Belák, Jind{hacek over (r)}ich Soukup, Brunhilde Schölzke, Britta von Oepen
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Patent number: 11730809Abstract: The present invention provides new multivalent vaccines for felines. The present invention also provides methods of making and using the multivalent vaccines alone or in combinations with other protective agents.Type: GrantFiled: September 29, 2021Date of Patent: August 22, 2023Assignee: Intervet Inc.Inventors: Zhichang Xu, Rhonda LaFleur, Ian Tarpey
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Publication number: 20230248817Abstract: The present invention relates to a nucleic acid construct comprising first, second and third nucleic acid sequences encoding first, second and third neuraminidase (NA) antigens of a Swine influenza A virus (IAV-S). The first NA antigen is of the A/swine/Scotland/410440/1994-like H1huN2 (Scot/94) lineage, the second NA antigen is of the A/swine/Gent/1/1984-like H3N2 (Gent/84) lineage, and the third NA antigen is selected from the A(H1N1)pdm09 (pdm09) lineage or the Eurasian avian-like H1avN1 (EA) lineage. In other embodiments, the present invention relates to RNA replicon particles comprising the nucleic acid construct, an immunogenic composition, such as a vaccine, which may be used against influenza A virus infection, and comprising the replicon particles.Type: ApplicationFiled: June 18, 2021Publication date: August 10, 2023Applicant: Intervet Inc.Inventors: Mark A. Mogler, Basav Hangalapura Nagaraj
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Publication number: 20230250177Abstract: The present invention provides compositions for treating canine atopic dermatitis that comprise a caninized anti-proliferative antibody, a caninized anti-pruritic antibody, and a caninized anti-inflammatory antibody. The present invention further relates to compositions that comprise a bispecific antibody that comprises a caninized anti -pruritic antibody and a caninized anti-proliferative antibody or alternatively a bispecific antibody comprising a caninized anti-pruritic antibody and a caninized anti-inflammatory antibody.Type: ApplicationFiled: December 18, 2020Publication date: August 10, 2023Applicant: Intervet Inc.Inventors: Mohamad Morsey, Yuanzheng Zhang, Anasuya Saha
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Patent number: 11712416Abstract: A solid oral pharmaceutical composition for delivery of a pharmaceutically acceptable active ingredient to an animal where the composition comprises an isoxazoline compound, a solvent and an excipient, a process for the manufacture of such solid oral pharmaceutical composition and a method of controlling a parasite infection administering such solid oral pharmaceutical composition.Type: GrantFiled: March 2, 2021Date of Patent: August 1, 2023Assignee: Intervet Inc.Inventors: Keith Freehauf, Niki Waldron, Jürgen Lutz, Frank Guerino
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Publication number: 20230233530Abstract: An implant for the control of parasites in livestock comprising an isoxazoline compound of Formula (I) or salt or solvate thereof, wherein the implant comprises one or more pellets each of which comprises the isoxaxoline compound and a pharmaceutically acceptable excipient and a method of preventing or treating a parasite infestation using the same.Type: ApplicationFiled: April 4, 2023Publication date: July 27, 2023Applicant: Intervet Inc.Inventors: Keith Freehauf, Anagha Avinash Bhakay
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Patent number: 11696944Abstract: The present invention pertains to a vaccine comprising an IgM protease antigen of Streptococcus suis, for use in a method for protecting pigs against an infection with Streptococcus suis of serotype 2 and against an infection with Streptococcus suis of serotype 14.Type: GrantFiled: November 7, 2019Date of Patent: July 11, 2023Assignee: Intervet Inc.Inventor: Antonius Arnoldus Christiaan Jacobs
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Publication number: 20230189767Abstract: A method for external fish parasite monitoring in aquaculture, comprising the steps of: submerging a camera (52) in a sea pen containing fish, the camera having a field of view; capturing images of the fish with the camera (52); and identifying external fish parasite on the fish by analyzing the captured images, characterized in that a target region within the field of view of the camera (52) is illuminated from above and below with light of different intensities and/or spectral compositions.Type: ApplicationFiled: November 23, 2022Publication date: June 22, 2023Applicant: Intervet Inc.Inventors: Russel Howe, Zachary Lizer, James Wallace Sarrett, Peter Jon Abrahamson, Jascha Tucker Little
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Patent number: 11680097Abstract: The present invention discloses antibodies to canine PD-1 that have specific sequences and a high binding affinity for canine PD-1. The invention also discloses the use of the antibodies of the present invention in the treatment of cancer in dogs.Type: GrantFiled: June 5, 2020Date of Patent: June 20, 2023Assignee: Intervet Inc.Inventors: Mohamad Morsey, Yuanzheng Zhang, Denise Bartels-Morozov, Jason Erskine, Ian Tarpey
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Publication number: 20230174996Abstract: The present invention is directed to a reassorted ISA virus comprising Genome segments 1-8 wherein at least one genome segment is from Genotype I and at least one genome segment is from genotype II, wherein genome segment 6 is of Genotype II. The reassorted ISA virus was found to grow well in suspension culture. The present invention is also directed to method to make the reassorted virus as well as vaccination methods using the reassorted ISA virus and to vaccine compositions comprising the reassorted ISA virus.Type: ApplicationFiled: December 18, 2020Publication date: June 8, 2023Applicant: Intervet Inc.Inventors: Stephane Villoing, Sven Leininger, Kjartan Hodneland, Joseph Koumans
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Patent number: 11659821Abstract: The present invention pertains to a method for automatic sea lice monitoring in fish aquaculture, the method comprising submerging a camera (4) in a sea pen (300) comprising fish, using the camera to make an image of at least one of said fish, analysing the image to differentiate between individual sea lice present on the fish and the fish itself and assessing the number of sea lice present on the fish, wherein the camera is attached to a device (1, 10, 100) for guiding the salmon along an imaging track (5), the camera being directed to the track.Type: GrantFiled: November 18, 2020Date of Patent: May 30, 2023Assignee: Intervet Inc.Inventors: Peter Jans, Evert Gijtenbeek