Patents Assigned to Intezyne Technologies, Inc.
  • SN-38 loaded iron crosslinked micelle and methods thereof
    Patent number: 10857147
    Abstract: The present invention provides SN-38 compositions for treating cancer.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: December 8, 2020
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Adam Carie
  • Block copolymers for stable micelles
    Patent number: 10047197
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: August 14, 2018
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Adam Carie
  • Block copolymers for stable micelles
    Patent number: 9944754
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: April 17, 2018
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Joseph Edward Semple, Tomas Vojkovsky
  • Block copolymers for stable micelles
    Patent number: 9944752
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: April 17, 2018
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Tomas Vojkovsky, Adam Carie, Joseph Edward Semple, Hooshmand Sheshbaradaran
  • Block copolymers for stable micelles
    Patent number: 9499665
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: November 22, 2016
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Tomas Vojkovsky, Adam Carie
  • Method of treating neuroendocrine tumors
    Patent number: 9089578
    Abstract: Methods and compositions for treating neuroendocrine tumors are disclosed.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: July 28, 2015
    Assignee: Intezyne Technologies, Inc.
    Inventors: Hooshmand Sheshbaradaran, William McCulloch
  • Block copolymers for stable micelles
    Patent number: 9078930
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 14, 2015
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Tomas Vojkovsky, Adam Carie
  • Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents
    Patent number: 8980326
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: March 17, 2015
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • POLYMER BASED POLYNUCLEOTIDE TRANSFECTION AGENTS
    Publication number: 20140302607
    Abstract: The present invention provides a methodology for transfecting cells in vitro. In particular, cationic polymers and polynucleotide containing polyplexes comprising such polymers are provided.
    Type: Application
    Filed: January 27, 2014
    Publication date: October 9, 2014
    Applicant: Intezyne Technologies, Inc.
    Inventor: Janni Mirosevich
  • COPOLYMERS FOR STABLE MICELLE FORMULATIONS
    Publication number: 20140271885
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Application
    Filed: February 11, 2014
    Publication date: September 18, 2014
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Tomas Vojkovsky
  • Polymeric micelles for drug delivery
    Patent number: 8779008
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: July 15, 2014
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • Polymeric micelles for polynucleotide encapsulation
    Patent number: 8747904
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: June 10, 2014
    Assignee: Intezyne Technologies, Inc.
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
  • BLOCK COPOLYMERS FOR STABLE MICELLES
    Publication number: 20140127271
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Application
    Filed: September 16, 2013
    Publication date: May 8, 2014
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Hooshmand Sheshbaradaran
  • BLOCK COPOLYMERS FOR STABLE MICELLES
    Publication number: 20140114051
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Application
    Filed: September 16, 2013
    Publication date: April 24, 2014
    Applicant: Intezyne Technologies, Inc.
    Inventor: Joseph Edward Semple
  • BLOCK COPOLYMERS FOR STABLE MICELLES
    Publication number: 20140113879
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Application
    Filed: September 16, 2013
    Publication date: April 24, 2014
    Applicant: Intezyne Technologies, Inc.
    Inventors: Adam Carie, Kevin Sill
  • Polymer micelles containing anthracyclines for the treatment of cancer
    Patent number: 8629186
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: January 14, 2014
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doris
  • Multi-block copolymers for the preparation of stabilized micelles
    Patent number: 8609146
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Grant
    Filed: September 17, 2012
    Date of Patent: December 17, 2013
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Habib Skaff
  • Poly(ethylene glycol) containing chemically disparate endgroups
    Patent number: 8609857
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: December 17, 2013
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin Sill, Habib Skaff
  • POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION
    Publication number: 20130266617
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: August 21, 2012
    Publication date: October 10, 2013
    Applicant: Intezyne Technologies, Inc.
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
  • POLYMERIC MICELLES FOR DRUG DELIVERY
    Publication number: 20130195987
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: December 19, 2012
    Publication date: August 1, 2013
    Applicant: INTEZYNE TECHNOLOGIES, INC.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp