Patents Assigned to Intezyne Technologies, Incorporated
  • POLYMER MICELLES CONTAINING ANTHRACYCLINES FOR THE TREATMENT OF CANCER
    Publication number: 20130309277
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: July 25, 2013
    Publication date: November 21, 2013
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
  • Polymer micelles containing anthracylines for the treatment of cancer
    Patent number: 8524784
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: September 3, 2013
    Assignee: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
  • Polymer micelles containing anthracylines for the treatment of cancer
    Patent number: 8524783
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: September 3, 2013
    Assignee: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria, Gregoire Cardoen
  • ATTACHMENT OF BIOLOGICAL TARGETING GROUPS USING METAL FREE CLICK CHEMISTRY
    Publication number: 20120283410
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same.
    Type: Application
    Filed: March 9, 2012
    Publication date: November 8, 2012
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Janni Mirosevich, Kevin Sill
  • PEGYLATED POLYPLEXES CONTAINING TWO OR MORE DIFFERENT POLYMERS FOR POLYNUCLEOTIDE DELIVERY
    Publication number: 20120237565
    Abstract: The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes.
    Type: Application
    Filed: March 9, 2012
    Publication date: September 20, 2012
    Applicant: INTEZYNE TECHNOLOGIES, INCORPORATED
    Inventors: Janni Mirosevich, Kevin Sill
  • SYNTHESIS OF HOMOPOLYMERS AND BLOCK COPOLYMERS
    Publication number: 20120196989
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.
    Type: Application
    Filed: March 13, 2012
    Publication date: August 2, 2012
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kurt Breitenkamp, Kevin N. Sill
  • PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY
    Publication number: 20120148631
    Abstract: The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes.
    Type: Application
    Filed: June 1, 2011
    Publication date: June 14, 2012
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill
  • PLASMA MODIFICATION OF METAL SURFACES
    Publication number: 20120046735
    Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
    Type: Application
    Filed: January 14, 2011
    Publication date: February 23, 2012
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY
    Publication number: 20110229528
    Abstract: The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes.
    Type: Application
    Filed: March 14, 2011
    Publication date: September 22, 2011
    Applicant: INTEZYNE TECHNOLOGIES, INCORPORATED
    Inventors: JANNI MIROSEVICH, KEVIN N. SILL, GREGOIRE CARDOEN
  • PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY
    Publication number: 20110142886
    Abstract: The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes.
    Type: Application
    Filed: December 1, 2010
    Publication date: June 16, 2011
    Applicant: INTEZYNE TECHNOLOGIES, INCORPORATED
    Inventors: JANNI MIROSEVICH, GREGOIRE CARDOEN, KEVIN N. SILL
  • POLYMER MICELLES CONTAINING ANTHRACYLINES FOR THE TREATMENT OF CANCER
    Publication number: 20110142950
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: October 29, 2010
    Publication date: June 16, 2011
    Applicant: INTEZYNE TECHNOLOGIES, INCORPORATED
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
  • POLYMERS FOR POLYNUCLEOTIDE ENCAPSULATION
    Publication number: 20100292432
    Abstract: The present invention provides block copolymers comprising hydrophobic moieties in a cationic complexing block, methods of preparing the same, and intermediates thereto. The compounds are useful in a variety of applications such as the assembly of micellar polyion complexes. The invention further provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: April 29, 2010
    Publication date: November 18, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Gregoire Cardoen, Kevin N. Sill, Janni Mirosevich, Habib Skaff
  • POLYMER MICELLES CONTAINING SN-38 FOR THE TREATMENT OF CANCER
    Publication number: 20100278932
    Abstract: The present invention provides micelles having SN-38 encapsulated therein.
    Type: Application
    Filed: May 4, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Adam Carie, Jonathan Rios-Doria, Richard Slama, Gregoire Cardoen
  • POLYMER MICELLES CONTAINING ANTHRACYLINES FOR THE TREATMENT OF CANCER
    Publication number: 20100278928
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: April 30, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Jonathan Rios-Doria, Habib Skaff, Gregoire Cardoen
  • POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION
    Publication number: 20100278927
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: April 29, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff