Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
Type:
Application
Filed:
July 22, 2013
Publication date:
November 21, 2013
Applicant:
Intezyne Technologies
Inventors:
Kurt Breitenkamp, Rebecca Breitenkamp, Kevin N. Sill, Habib Skaff
Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
Type:
Application
Filed:
July 25, 2013
Publication date:
November 21, 2013
Applicant:
Intezyne Technologies, Incorporated
Inventors:
Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
Type:
Application
Filed:
August 21, 2012
Publication date:
October 10, 2013
Applicant:
Intezyne Technologies, Inc.
Inventors:
Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
Type:
Grant
Filed:
October 29, 2010
Date of Patent:
September 3, 2013
Assignee:
Intezyne Technologies, Incorporated
Inventors:
Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
Type:
Grant
Filed:
April 30, 2010
Date of Patent:
September 3, 2013
Assignee:
Intezyne Technologies, Incorporated
Inventors:
Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria, Gregoire Cardoen
Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
Type:
Grant
Filed:
July 31, 2012
Date of Patent:
April 23, 2013
Assignee:
Intezyne Technologies, LLC
Inventors:
Kurt Breitenkamp, Kevin Sill, Habib Skaff, Rebecca Breitenkamp
Abstract: The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same.
Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
Type:
Grant
Filed:
December 7, 2010
Date of Patent:
October 30, 2012
Assignee:
Intezyne Technologies, Inc.
Inventors:
Kevin N. Sill, Habib Skaff, Kurt Breitenkamp, Rebecca Breitenkamp
Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
Type:
Grant
Filed:
April 29, 2010
Date of Patent:
October 16, 2012
Assignee:
Intezyne Technologies, Inc.
Inventors:
Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.
Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
Type:
Grant
Filed:
December 22, 2009
Date of Patent:
September 11, 2012
Assignee:
Intezyne Technologies, Inc.
Inventors:
Kevin N. Sill, Habib Skaff, Kurt Breitenkamp, Rebecca Breitenkamp
Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
Type:
Grant
Filed:
December 7, 2010
Date of Patent:
September 11, 2012
Assignee:
Intezyne Technologies, Inc.
Inventors:
Kevin N. Sill, Habib Skaff, Kurt Breitenkamp, Rebecca Breitenkamp
Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
Type:
Application
Filed:
May 14, 2012
Publication date:
September 6, 2012
Applicant:
Intezyne Technologies, Inc.
Inventors:
Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated contrast agents and methods for using the same.
Type:
Grant
Filed:
April 30, 2008
Date of Patent:
September 4, 2012
Assignee:
Intezyne Technologies, Inc.
Inventors:
Habib Skaff, Kurt Breitenkamp, Kevin N. Sill
Abstract: The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.
Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
Type:
Grant
Filed:
April 27, 2007
Date of Patent:
July 3, 2012
Assignee:
Intezyne Technologies, Inc.
Inventors:
Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
Type:
Grant
Filed:
February 17, 2010
Date of Patent:
June 26, 2012
Assignee:
Intezyne Technologies, Inc.
Inventors:
Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
Abstract: The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes.
Type:
Application
Filed:
June 1, 2011
Publication date:
June 14, 2012
Applicant:
Intezyne Technologies, Incorporated
Inventors:
Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill
Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
Type:
Application
Filed:
January 14, 2011
Publication date:
February 23, 2012
Applicant:
Intezyne Technologies, Incorporated
Inventors:
Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
Type:
Grant
Filed:
July 9, 2007
Date of Patent:
November 29, 2011
Assignee:
Intezyne Technologies, Inc.
Inventors:
Kurt Breitenkamp, Rebecca Breitenkamp, Kevin N. Sill, Habib Skaff