Patents Assigned to Intezyne Technologies
  • Publication number: 20130310912
    Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
    Type: Application
    Filed: July 22, 2013
    Publication date: November 21, 2013
    Applicant: Intezyne Technologies
    Inventors: Kurt Breitenkamp, Rebecca Breitenkamp, Kevin N. Sill, Habib Skaff
  • Publication number: 20130309277
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: July 25, 2013
    Publication date: November 21, 2013
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
  • Publication number: 20130266617
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: August 21, 2012
    Publication date: October 10, 2013
    Applicant: Intezyne Technologies, Inc.
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
  • Patent number: 8524784
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: September 3, 2013
    Assignee: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
  • Patent number: 8524783
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: September 3, 2013
    Assignee: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria, Gregoire Cardoen
  • Patent number: 8426477
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: April 23, 2013
    Assignee: Intezyne Technologies, LLC
    Inventors: Kurt Breitenkamp, Kevin Sill, Habib Skaff, Rebecca Breitenkamp
  • Publication number: 20120283410
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same.
    Type: Application
    Filed: March 9, 2012
    Publication date: November 8, 2012
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Janni Mirosevich, Kevin Sill
  • Patent number: 8299128
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: October 30, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp, Rebecca Breitenkamp
  • Patent number: 8287910
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: October 16, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
  • Patent number: 8268936
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: September 18, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill
  • Patent number: 8263665
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: September 11, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp, Rebecca Breitenkamp
  • Patent number: 8263663
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: September 11, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp, Rebecca Breitenkamp
  • Publication number: 20120226050
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: May 14, 2012
    Publication date: September 6, 2012
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • Patent number: 8258190
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated contrast agents and methods for using the same.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: September 4, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Habib Skaff, Kurt Breitenkamp, Kevin N. Sill
  • Publication number: 20120196989
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.
    Type: Application
    Filed: March 13, 2012
    Publication date: August 2, 2012
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kurt Breitenkamp, Kevin N. Sill
  • Patent number: 8212083
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: July 3, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • Patent number: 8207353
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: June 26, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • Publication number: 20120148631
    Abstract: The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes.
    Type: Application
    Filed: June 1, 2011
    Publication date: June 14, 2012
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill
  • Publication number: 20120046735
    Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
    Type: Application
    Filed: January 14, 2011
    Publication date: February 23, 2012
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • Patent number: 8066824
    Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: November 29, 2011
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Rebecca Breitenkamp, Kevin N. Sill, Habib Skaff