Patents Assigned to Introgene
  • Retrovirus infecting primate bone marrow cells and harvesting both non-adherent and adherent cells
    Patent number: 5612206
    Abstract: A method is described for preparing primate bone marrow cells containing a DNA sequence of interest the method being first the isolation of bone marrow cells from a primate and then co-culturing the bone marrow cells with retrovirus producer cells. The retrovirus contains the DNA sequence of interest and infects the bone marrow cells during co-culture. To obtain bone marrow cells that contain the DNA sequence of interest, non-adherent bone marrow cells and adherent cells are harvested.
    Type: Grant
    Filed: June 21, 1994
    Date of Patent: March 18, 1997
    Assignee: Introgene B.V.
    Inventors: Domenico Valerio, Victor W. van Beusechem