Abstract: A novel pharmaceutical composition including thieno-pyridine derivatives, primarily ticlopidine hydrochloride, having no other organic or inorganic acid stabilizing agents or metal stearates. The stable pharmaceutical composition also includes hydrogenated vegetable oil as lubricant and other suitable non-ionic inert pharmaceutical excipients.

Abstract: A solid pharmaceutical tablet having a predetermined dosage that can be divided into a plurality of sub-dosage units by applying a minimal amount of force to the tablet. The tablet comprises a solid body having a top surface, a bottom surface, an outer surface, and an inner surface. The inner surface defines an aperture having a shape corresponding to the shape of the tablet. The area of the aperture is at least 15% of the area of the tablet. Impressed within the top surface of the tablet are a first plurality of symmetrical score lines and impressed within the bottom surface of the tablet are a second plurality of symmetrical score lines. The score lines extend from the aperture to the outer surface of the tablet. Finally, each of the sub-dosage units has a dosage that is a fraction of the predetermined dosage of the tablet.

Abstract: A safety shielded, reusable trocar consisting of a trocar cannula subassembly, a safety shield control mechanism, and a separate obturator subassembly. The trocar cannula subassembly includes an outer cannula attached to a main housing having a central bore in which a spring biased, inner cannula is slidably and removably inserted, and an upper housing, removably secured to the main housing, having a central bore which is aligned longitudinally with the bore of the main housing and in which sealing means is removably secured. The obturator subassembly includes an elongated obturator having a replaceable and rotatable knife, an elongated shaft, an arcuate shaped cap, and which extends through the upper housing, sealing means, main housing, inner cannula, and outer cannula.

Abstract: The present invention relates to the discovery of novel polymorph form of an active pharmaceutical agent and the process for its preparation. More specifically, the present invention relates to the preparation of a novel polymorph form of terazosin hydrochloride, a well known anti-hypertensive agent.