Abstract: A device comprising: a tubular anchoring element configured and dimensioned for implanting about a multifurcation zone of a body lumen dividing a main vessel into at least two branches, to anchor the device therein; a removable sleeve defined by a tubular sidewall, the removable sleeve e being dimensioned for being removably received within a lumen of the anchoring element and extending therein at least the multifurcation zone, wherein the removable sleeve is self-expandable from a radially compressed state defining a delivery configuration into the anchoring element, to a radially expanded state defining a fully expanded configuration, wherein at least a portion of the sidewall, the portion encompassing at least inlets of the at least two branches, comprises a mesh having a mesh size sufficient to allow passage of blood and to deflect the flow of embolic material exceeding a predetermined size.

Abstract: A device (10) includes an upstream tubular portion (12) from which extends a downstream constriction (14). The downstream constriction (14) is smaller in cross-sectional area than the upstream tubular portion (12). Velocity of fluid flowing through the downstream constriction (14) is greater than velocity of the fluid flowing in the upstream tubular portion (12). A permeable downstream portion (20) is distal to the upstream tubular portion (12). The permeable downstream portion (20) is formed with pores (22) so that the downstream portion (20) is more permeable for fluid flow laterally therethrough than the upstream tubular portion (12).