Abstract: The present invention relates to single-domain antibodies (sdAbs) directed against Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2), pharmaceutical compositions comprising
Type:
Application
Filed:
September 18, 2020
Publication date:
July 27, 2023
Applicant:
Invectys SAS
Inventors:
Maria LOUSTAU, Lise HUNAULT, Pierre LANGLADE DEMOYEN, Julien CAUMARTIN
Abstract: The invention relates a recombinant measles virus plasmid capable of expressing a human telomerase reverse transcriptase (hTERT) protein fused at N-terminus with a protein enhancing addressing of the hTERT protein to proteasome. The invention further relates to a vaccine comprising said plasmid or particles rescued therefrom, and uses thereof, especially in preventing or treating a tumor in a patient.
Type:
Grant
Filed:
May 7, 2018
Date of Patent:
June 7, 2022
Assignees:
INVECTYS SAS, INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Pierre Langlade Demoyen, Frédéric Tangy, Elodie Pliquet