Abstract: A surgical system for blocking a luminal body at a selected location has a tubular body that extends from a proximal end to a distal end, and a blocking device on the distal end of the tubular body. The blocking device has a guide cap and a gripping feature, and at least one annular inflatable portion positioned around an outer circumference of the gripping feature. A first conduit through the tubular body is connected to a pressure source for inflating the annular inflatable portion, and a second conduit through the tubular body is connected to a vacuum source for suctioning a luminal wall of the luminal body against the gripping feature.