Patents Assigned to Invetx, Inc.
  • Anti-NGF antibodies and uses thereof
    Patent number: 12378308
    Abstract: The invention provides novel anti-NGF proteins, antibodies, and NGF-binding fragments thereof which inhibit association of NGF with TrkA and/or p75 and are suitable for administration to a canine or feline subject. The invention also provides novel compositions and methods of treating pain or eliciting an analgesic effect in a canine or feline subject, comprising administering an effective amount of an anti-NGF protein, antibody or fragment thereof. The methods and compositions are used to treat or prevent NGF-related disorders.
    Type: Grant
    Filed: January 23, 2024
    Date of Patent: August 5, 2025
    Assignee: INVETX, INC.
    Inventors: William Brondyk, Jordan Willis, Leila Sevigny
  • Compositions for increasing half-life of a therapeutic agent in felines and methods of use
    Patent number: 12344650
    Abstract: Provided are compositions for increasing the half-life of a polypeptide or polypeptides in a feline and methods of their use. The compositions involve variant feline IgG Fc regions.
    Type: Grant
    Filed: October 12, 2022
    Date of Patent: July 1, 2025
    Assignee: Invetx, Inc.
    Inventors: William Brondyk, Brett Chevalier, Juergen Horn, Madhusudan Natarajan
  • Anti-NGF antibodies and uses thereof
    Patent number: 12110322
    Abstract: The invention provides novel anti-NGF proteins, antibodies, and NGF-binding fragments thereof which inhibit association of NGF with TrkA and/or p75 and are suitable for administration to a canine or feline subject. The invention also provides novel compositions and methods of treating pain or eliciting an analgesic effect in a canine or feline subject, comprising administering an effective amount of an anti-NGF protein, antibody or fragment thereof. The methods and compositions are used to treat or prevent NGF-related disorders.
    Type: Grant
    Filed: July 6, 2023
    Date of Patent: October 8, 2024
    Assignee: INVETX, INC.
    Inventors: William Brondyk, Jordan Willis, Leila Sevigny
  • Compositions for increasing half-life of a therapeutic agent in livestock animals and methods of use
    Patent number: 12103961
    Abstract: Provided are compositions for increasing the half-life of a polypeptide or polypeptides in a livestock animal and methods of their use. The compositions involve variant IgG Fc regions.
    Type: Grant
    Filed: December 1, 2021
    Date of Patent: October 1, 2024
    Assignee: Invetx, Inc.
    Inventors: William Brondyk, Juergen Horn
  • Compositions for increasing half-life of a therapeutic agent in felines and methods of use
    Patent number: 11739135
    Abstract: Provided are compositions for increasing the half-life of a polypeptide or polypeptides in a feline and methods of their use. The compositions involve variant feline IgG Fc regions.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: August 29, 2023
    Assignee: Invetx, Inc.
    Inventors: William Brondyk, Brett Chevalier, Juergen Horn, Madhusudan Natarajan
  • Compositions for increasing half-life of a therapeutic agent in canines and methods of use
    Patent number: 11548949
    Abstract: Provided are compositions for increasing the half-life of a polypeptide or polypeptides in a canine and methods of their use. The compositions involve variant canine IgG Fc regions.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: January 10, 2023
    Assignee: Invetx, Inc.
    Inventors: William Brondyk, Brett Chevalier, Juergen Horn, Madhusudan Natarajan
  • Compositions for increasing half-life of a therapeutic agent in canines and methods of use
    Patent number: 11542333
    Abstract: Provided are compositions for increasing the half-life of a polypeptide or polypeptides in a canine and methods of their use. The compositions involve variant canine IgG Fc regions.
    Type: Grant
    Filed: January 2, 2020
    Date of Patent: January 3, 2023
    Assignee: Invetx, Inc.
    Inventors: William Brondyk, Brett Chevalier, Juergen Horn, Madhusudan Natarajan
  • Compositions for increasing half-life of a therapeutic agent in felines and methods of use
    Patent number: 11498953
    Abstract: Provided are compositions for increasing the half-life of a polypeptide or polypeptides in a feline and methods of their use. The compositions involve variant feline IgG Fc regions.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: November 15, 2022
    Assignee: Invetx, Inc.
    Inventors: William Brondyk, Brett Chevalier, Juergen Horn, Madhusudan Natarajan
  • Polypeptides with altered binding to neonatal Fc receptor (FcRn) and methods of use
    Patent number: 11434276
    Abstract: Provided are compositions for increasing the half-life of a polypeptide or polypeptides in a canine and methods of their use. The compositions involve variant canine IgG Fc regions.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: September 6, 2022
    Assignee: Invetx, Inc.
    Inventors: William Brondyk, Brett Chevalier, Juergen Horn, Madhusudan Natarajan