Abstract: Lowering of intraocular pressure, e.g. in the treatment of glaucoma is carried out by administering a phosphodiesterase inhibitor to a patient. Particular ophthalmic pharmaceutical compositions are disclosed for topical application to the eye.

Abstract: Lowering of intraocular pressure, e.g. in the treatment of glaucoma is carried out by administering a phosphodiesterase inhibitor to a patient. Particular ophthalmic pharmaceutical compositions are disclosed for topical application to the eye.

Abstract: An insertion tool for an intraocular lens including a disposable insertion assembly and a reusable handle. The insertion assembly includes a rigid tube with a collar about its proximal end and a lens holder which slides within the rigid tube and also includes a collar on its proximal end and a paddle on its distal end. The handle includes a hollow barrel connected to the rigid tube collar and a driver barrel inside the barrel connected to the collar of the lens holder. An actuator button slides along the outside of the barrel and extends through a slot in the side of the barrel to engage the drive barrel. A pusher rod may be placed inside the bore of the drive barrel to help hold the lens in position.

Abstract: Rodocaine or a pharmaceutically-acceptable salt thereof has been found to be an effective anesthetic in ophthalmology. Topical and injectable formulations are disclosed.

Abstract: An insertion tool for an intraocular lens including a hollow barrel, a rigid annular tube extending from the distal end of the barrel, the stylet for reciprocating within the barrel and the rigid tube, an actuator extending through the side wall of the barrel and connected to the stylet to permit the user to move the stylet back and forth within the barrel. A paddle is attached to the distal end of the stylet. The intraocular lens is loaded into the paddle and then the paddle and the lens are retracted into the rigid tube for insertion into the eye through a small incision. The paddle unfolds the lens as it is retracted into the tube. When the distal end of the instrument is placed into the eye, the paddle and lens are ejected from the tube so that the lens may be deposited within the eye.

Abstract: An optic for an intraocular lens with finished, molded radii on the anterior and posterior edges of the peripheral surface of the optic. The optic has a thin central optical zone and a surrounding annular ring having sufficient material to support haptics. The ring is thicker than the optical zone and, thus, recesses the posterior surface of the optical zone to provide a capsulotomy space. The present novel optic is produced by novel molding pins which are shaped to provide the finished molded radii on the edges of the optic so that the optic requires little or no post-molding finishing or polishing other than the degating and deflashing.

Abstract: Vinylsilylalkoxy arylbenzotriazol monomers such as 2-[3'-t-butyl-5'-(3-"-dimethylvinylsilylpropoxy)-2'-hydroxy-phenyl]-5-meth oxybenzotriazole are disclosed. These monomers can be incorporated in optically clear silicone polymers to form intraocular lenses, contact lenses, and the like, which have UV absorbing properties.

Abstract: An optic for an intraocular lens with finished, molded radii on the anterior and posterior edges of the peripheral surface of the optic. The optic has a thin central optical zone and a surrounding annular ring having sufficient material to support haptics. The ring is thicker than the optical zone and, thus, recesses the posterior surface of the optical zone to provide a capsulotomy space. The present novel optic is produced by novel molding pins which are shaped to provide the finished molded radii on the edges of the optic so that the optic requires little or no post-molding finishing or polishing other than the degating and deflashing.

Abstract: A low glare intraocular lens optic using partial depth positioning holes.

Abstract: Ultraviolet light absorbing compositions comprising 2-(2'-hydroxy-5'-acryloyloxyalkoxyphenyl(-2H-benzotrizoles, and copolymers thereof with one or more other monomers copolyermizable therewith, particularly acrylic monomers, are useful in the manufacture of ocular devices, particularly intraocular lenses and contact lenses.

Abstract: A soft intraocular lens suitable for placement in the anterior or posterior chamber and either in or out of the capsular bag. The lens has a fenestrated haptic defined by an arcuate member including a tissue contact portion, beam portions and support portions which acting together keep the lens in contact with the eye during distortion and tend to cause the lens to vault posteriorly when compressed.

Abstract: A surgical instrument to facilitate the insertion and allow better control of the superior haptic of an intraocular lens into the capsular bag of the eye. The instrument includes a hollow cannula with a beveled distal tip and a tapered slot extending proximally from the distal tip of the cannula. A stylet slides freely within the cannula and has a distal tip beveled at an angle corresponding to the bevel of the distal tip of the cannula. A handle is provided for supporting the cannula and the stylet and includes a mechanism for advancing the stylet distally to align the beveled distal tips of the cannula and the stylus to form a plane which resolves the forces exerted by the resilient haptic in a direction which urges the haptic into the capsular bag.

Abstract: An insertion guide for aiding the insertion of the superior haptic of an intraocular lens into the capsular bag of the eye during intraocular surgery. The guide is made of a thin, flexible material and has a body portion and a flap portion connected by an integral connecting portion which permits the flap to move from the first position folded against the body portion to a second position where the flap is disposed at an acute angle to the body portion so that the flap will act as a backstop to guide the superior haptic of an intraocular lens into the capsular bag. The present invention also relates to the method of inserting an intraocular lens using this guide.

Abstract: An insertion guide for aiding the insertion of the superior haptic of an intraocular lens into the capsular bag of the eye during intraocular surgery. The guide is made of a thin, flexible material and has a body portion and a flap portion connected by an integral connecting portion which permits the flap to move from the first position folded against the body portion to a second position where the flap is disposed at an acute angle to the body portion so that the flap will act as a backstop to guide the superior haptic of an intraocular lens into the capsular bag. The present invention also relates to the method of inserting an intraocular lens using this guide.

Abstract: The compounds 2'-hydroxy-5'-(hydroxyalkyl)phenyl-2H-benzotriazoles are useful as intermediate alcohols in the preparation of corresponding 2'-hydroxy-5'-acrylyloxyphenyl-2H-benzotriazole monomers, which in turn are copolymerizable with ethylenically unsaturated monomers, particularly acrylic monomers, to impart ultraviolet absorbing properties to the resulting copolymers.

Abstract: A fixture for holding an optical lens during processing which includes a first lens holder having a lens-covering surface and an exterior surface and a second lens holder with a lens-covering surface and an exterior surface. The lens-covering surfaces are placed over the confronting surface of a lens, and the entire assembly is clipped together so that it may be subjected to the manufacturing processes, for example abrasive tumbling to round the exposed edges of the lens.

Abstract: An intraocular lens loop, with an eyelet formed on the loop, and a method of forming the eyelet employing ultrasound energy. There is also disclosed a special fixture for use in manufacturing the eyelet loop.

Abstract: A process and apparatus for dissipating static electrical charge that may build up on the small plastic parts, the tumbling medium or the tumbling chamber itself during an abrasive tumbling process and cause the parts to be repelled out of the abrasive medium. A flow of ionized gas is distributed about the tumbling chamber, discharges the parts and provides a mechanical action to return the parts to the abrasive medium. This flow of ionized gas dissipates the static charge.

Abstract: A universal anterior chamber lens having an optic with bores entering into the edge of the optic at points spaced circumferentially apart about 180.degree.. The optic is supported in the anterior chamber by haptics, each of which have a first end fixed to the optic, a first leg extending from the optic to the peripheral anatomy of the eye, a second leg extending transverse to the optic in contact with the anatomy of the eye and a third leg extending back toward the optic. The first leg includes a concave spring-like section extending toward the third leg. The free end of the third leg extends into the bore provided in the optic so that as the haptics compress, the free end of the haptic can ride freely in the optic bore. A locking mechanism holds the free end of the haptic in the bore.