Abstract: A particle therapy apparatus configured to scan a charged particle beam over a target according to a pre-defined treatment field which covers a treatment surface in an isocenter plane of the apparatus. The apparatus is capable of scanning the beam over a reachable surface which covers and is larger than the treatment surface. A beam stopper is arranged downstream of the scanning magnets of the apparatus, at a position to prevent the beam from reaching at least a portion of the reachable surface and to allow the beam to reach any portion of the treatment surface. A control system is configured to control the apparatus to direct the beam to the beam stopper and to meanwhile measure a position of the beam, to calculate a difference between a desired position and the measured position of the beam when directed to the beam stopper, and to scan the beam over the target according to the pre-defined treatment field by taking into account the calculated difference.

Abstract: A method for assessing a quality of a beam shaping device includes, establishing with a treatment planning system (TPS) the planned device design of the beam shaping device, manufacturing the beam shaping device according to the planned device design, establishing a CT-scan of the beam shaping device to yield an actual CT-image, determining dimensions and local materials densities from the actual CT-image, determining a calculated dose distribution in the treatment volume (V), and comparing the calculated dose distribution (cDD) with a reference dose distribution (rDD).

Abstract: A computer-based method for generating one or more FTA fault trees from an FMEA table of a technical system or vice versa. The method includes defining a common data set for both the FMEA table and the one or more FTA fault tree(s) of the technical system, obtaining data of the common data set for the technical system, selecting a representation of the technical system as a FMEA table or as one or more FTA fault tree(s), and using the data of the common data for generating and displaying on a graphical user interface the FMEA table of the technical system or one or more FTA fault tree(s) of the technical system, depending on the selected representation.

Abstract: A treatment device includes a pulsed particles accelerator and a processor for controlling the latter to deliver a treatment plan by deposition at HDR of charged particles into a flash volume (Vht) by PBS. To shorten the time for depositing a target dose (Dti) into the cells spanned by the flash spots (Si) of the flash volume (Vht), the flash spots are combined into k sets of n flash spots (Si). After depositing a jth pulse dose (Dij) into the cells spanned by a ith flash spot (Si) the beam commutes from the ith flash spot (Si) to a next (i+1)th flash spot according to a flash scanning subsequence to deposit a jth dose into the cells spanned by each of the subsequent flash spots of the flash scanning subsequence, until returning to the ith flash spot to deposit a (j+1)th dose (Di(j+1)), and so on When all the cells spanned by all the flash spots of a set have received their corresponding target dose, the beam moves to a next set of combined flash spots and repeats the foregoing pulse deposition steps.

Abstract: The present invention concerns a method for designing a ridge filter for a charged particle accelerator, for depositing with beams of accelerated particles (100.i) specific doses (Dij) into specific locations within a treatment volume (V) of tissue comprising tumoral cells (3t) by single layer pencil beam scanning (PBS), according to a predefined treatment plan (TP), the method comprising the following steps, Defining an array of spots (Si) defining the bases of cylindrical subvolumes (Vi) defining the treatment volume (V); the subvolumes (Vi) are divided into N cells (Cij). The ridge filter is designed comprising the same number of energy degrading units (11.i) as there are spots (Si). Each energy degrading unit (11.i) is formed by N cylindrical degrading subunits (11.ij) of lengths (Lij) and area (Aij). The lengths (Lij) of each degrading subunit (11.

Abstract: The present invention concerns an apparatus for irradiating goods with X-rays, comprising a first source of X-rays configured for emitting X-rays along a first irradiation volume centered on a longitudinal axis (X), and a conveyor configured for driving goods such as to expose a first portion of the goods through the first irradiation volume, wherein, the conveyor is configured for driving the target products through the irradiation volume along a vertical axis (Z).

Abstract: The embodiments of the present disclosure provide a method for producing Ac-225 from Ra-226, comprising submitting Ra-226 to a photo-nuclear process, collecting an electrochemical precipitation of an Ac-225 on a cathode in a recipient, removing the cathode from the recipient after the electrochemical precipitation of the Ac-225, transferring the cathode to a hot cell environment, and extracting the Ac-225 from the cathode in the hot cell environment. The Ra-226 may comprise a liquid solution in the recipient, and submitting Ra-226 to the photo-nuclear process may comprise irradiating the Ra-226 to produce Ra-225. The Ra-225 may decay into Ac-225 upon irradiation of the Ra-226.

Abstract: A treatment planning system for generating a plan for treatment by radiation with charged particles beams applied by pencil beam scanning onto a target tissue comprising tumoral cells is provided. The treatment planning system performs a dose definition stage defining the doses to be deposited within the peripheral surface, a beam definition stage defining positions and dimensions of the beamlets of the PBS during the at least one high rate fraction, the beams definition stage including a dose rate definition stage comprising at least one high rate fraction, and a beamlets scanning sequence stage defining a scanning sequence of irradiation of the beamlets. The beamlets scanning sequence stage optimizes a time sequence of beamlets emission such that at the end of a fraction j, a dose is deposited onto at least a predefined fraction of each specific volume at a mean deposition rate superior or equal to a predefined value.

Abstract: A radiotherapy apparatus for the delivery of an energetic beam to a target tissue in a treatment zone, including: a rotatable gantry for rotating the end of a beam delivery system about a circle centered on an isocentre and normal to an axis of rotation Z1 of the gantry, the path between the end of the beam delivery system and the isocentre defining a central beam axis Z2 at every rotation angle of the gantry about the axis of rotation Z1; an imaging ring having a central bore and an imaging system for acquiring images of a patient in an imaging zone of the imaging system, wherein the imaging ring is located in the radiotherapy apparatus such that its imaging zone intersects the axis of rotation Z1 of the gantry, and wherein the imaging ring is mechanically coupled to the rotatable gantry through a mechanical structure.

Abstract: A radiotherapy apparatus for the delivery of an energetic beam to a target tissue in a treatment zone, including: a rotatable gantry for rotating the end of a beam delivery system about a circle centered on an isocentre and normal to an axis of rotation Z1 of the gantry, the path between the end of the beam delivery system and the isocentre defining a central beam axis Z2 at every rotation angle of the gantry about the axis of rotation Z1; an imaging ring having a central bore and an imaging system for acquiring images of a patient in an imaging zone of the imaging system, wherein the imaging ring is located in the radiotherapy apparatus such that its imaging zone intersects the axis of rotation Z1 of the gantry, and wherein the imaging ring is mechanically coupled to the rotatable gantry through a mechanical structure.

Abstract: The present invention concerns an apparatus for irradiating goods with X-rays, comprising a first source of X-rays configured for emitting X-rays along a first irradiation volume centered on a longitudinal axis (X), and a conveyor configured for driving goods such as to expose a first portion of the goods through the first irradiation volume, wherein, the conveyor is configured for driving the target products through the irradiation volume along a vertical axis (Z).

Abstract: The embodiments of the present disclosure provide a method for producing Ac-225 from Ra-226, comprising submitting Ra-226 to a photo-nuclear process, collecting an electrochemical precipitation of an Ac-225 on a cathode in a recipient, removing the cathode from the recipient after the electrochemical precipitation of the Ac-225, transferring the cathode to a hot cell environment, and extracting the Ac-225 from the cathode in the hot cell environment. The Ra-226 may comprise a liquid solution in the recipient, and submitting Ra-226 to the photo-nuclear process may comprise irradiating the Ra-226 to produce Ra-225. The Ra-225 may decay into Ac-225 upon irradiation of the Ra-226.

Abstract: The present disclosure relates to a particle therapy system for irradiating a target with a scanning beam technique. In one implementation, the system includes an irradiation planning device with a planning algorithm configured to associate a particle beam energy E(i) to each spot of the irradiation plan and organize the spots in a sequence of spots according to energy. The system may further include a control system configured for controlling in parallel, from spot to spot, a variation of an output energy of a beam generator, a variation of a magnetic field of one or more electromagnets of a beam transport system and a variation of a magnetic field of the scanning magnet.

Abstract: The present invention relates to an RF system (1) able to generate a voltage for accelerating charged particles in a synchrocyclotron, the RF system (1) including a resonant cavity (2) comprising a conducting enclosure (5) within which are placed a conducting pillar (3) of which a first end is linked to an accelerating electrode (4) able to accelerate the charged particles, a rotary variable capacitor (10) coupled between a second end opposite from the first end of the pillar (3) and the conducting enclosure (5), the said capacitor (10) comprising fixed electrodes (11) and a rotor (13) comprising mobile electrodes (12), the fixed electrodes (11) and the mobile electrodes (12) forming a variable capacitance able to vary a resonant frequency of the resonant cavity (2) in a cyclic manner over time, an exterior layer of the rotor (13) having a conductivity of greater than 20,000,000 S/m at 300 K.

Abstract: RF device (1) able to generate an RF acceleration voltage in a synchrocyclotron. The device comprises a resonant cavity (2) formed by a grounded conducting enclosure (5) and enveloping a conducting pillar (3) to a first end of which an accelerating electrode (4) is linked. A rotary variable capacitor (10) is mounted in the conducting enclosure at a second end of the pillar, opposite from the first end, comprising at least one fixed electrode (stator) (11) and a rotor (13) exhibiting a rotation shaft (14) supported and guided in rotation by galvanically isolating bearings (20), said rotor (13) comprising one moveable electrode (12) possibly facing the stator (11). When the shaft (14) rotates, the stator and the moveable electrode together form a variable capacitance whose value varies cyclically with time. The rotor (13) is galvanically isolated from the conducting enclosure (5) and from the pillar (3). The stator (11) is connected to the second end of the pillar (3) or to the conducting enclosure (5).

Abstract: RF device (1) able to generate an RF acceleration voltage in a synchrocyclotron. The device comprises a resonant cavity (2) formed by a grounded conducting enclosure (5) and enveloping a conducting pillar (3) to a first end of which an accelerating electrode (4) is linked. A rotary variable capacitor (10) is mounted in the conducting enclosure at a second end of the pillar, opposite from the first end, comprising at least one fixed electrode (stator) (11) and a rotor (13) exhibiting a rotation shaft (14) supported and guided in rotation by galvanically isolating bearings (20), said rotor (13) comprising one moveable electrode (12) possibly facing the stator (11). When the shaft (14) rotates, the stator and the moveable electrode together form a variable capacitance whose value varies cyclically with time. The rotor (13) is galvanically isolated from the conducting enclosure (5) and from the pillar (3). The stator (11) is connected to the second end of the pillar (3) or to the conducting enclosure (5).

Abstract: The present invention relates to a particle therapy apparatus used for radiation therapy. More particularly, this invention relates to a compact isocentric gantry for delivering particle beams perpendicularly to a rotation axis of the gantry. The gantry comprises three dipole magnets. The angle of the last dipole magnet is smaller than 90° and a most preferred bending angle for this last dipole magnet is 60°.

Abstract: Methods and assembly for delivering a particle beam dose to a moving target are provided. The assembly comprises breath holding means for holding a patients breath during the delivery of the particle beam dose. With the assembly and method of invention, visualization means are provided to the patient to visualize the moving target such that the patient can actively contribute to the target positioning before actuating the breath holding means and starting the delivery of the particle beam.

Abstract: The present invention relates to a particle therapy apparatus used for radiation therapy. More particularly, this invention relates to a compact isocentric gantry for delivering particle beams perpendicularly to a rotation axis of the gantry . The gantry comprises three dipole magnets. The angle of the last dipole magnet is smaller than 90° and a most preferred bending angle for this last dipole magnet is 60°.

Abstract: The present invention relates to a dual-frequency resonant cavity (6) for cyclotron which includes a dee (10), a pillar (20), and a conducting enclosure (40) surrounding the pillar and the dee, an end of the pillar being connected to the base of the conducting enclosure and an opposite end of the pillar (20) supporting the dee (10). The conducting enclosure and the pillar form a transmission line comprising at least three portions (20a, 20b, 20c), each portion having a characteristic impedance (Zc1, Zc2, Zc3). The characteristic impedance Zc2 of the intermediate portion (20b) is substantially lower than the characteristic impedances Zc1 et Zc3 of the two other portions (20a, 20b), which makes it possible to have the cavity resonate according to two modes in order to produce two distinct frequencies, without having to make use of moving components such as for example sliding short-circuits or mobile plates.