Abstract: An RF power combiner/divider that combines a plurality of inputs into a combined output and comprises an isolating circuit coupling the inputs to a common floating point is provided. The isolating circuit includes a grounded resonant cavity inside which transmission lines are arranged, each of the transmission lines having a first end respectively connected to one of the inputs and an opposite second end connected to a grounded resistor arranged outside of the resonant cavity. Each of the transmission lines is coupled to a coupling portion of the resonant cavity, one end of the coupling portion being connected to ground and an opposite end of the coupling portion forming the common floating point.

Abstract: The disclosure provides a phantom and method for quality assurance of a hadron therapy apparatus used in the intensity modulated particle therapy mode. The phantom comprises a frame structure comprising a base plate, one or more energy wedges, an energy wedge first face inclined with respect to said base plate and an energy wedge second face perpendicular to said base plate, said one or more energy wedges being mounted on said base plate, a 2D detector; said one or more wedges, and 2D detector being in known fixed positions in relation to said frame structure. Said phantom comprises in addition a Spread-Out Bragg Peak wedge, said SOBP wedge having an SOBP wedge first face inclined with respect to said base plate, and a SOBP wedge second face, perpendicular to said base plate, said SOBP wedge being made of a material having a relative density higher than 1.3 preferably 1.5, more preferably 1.

Abstract: The present disclosure relates to scintillating detector systems for radiation therapy beams. In one implementation, a detector system for evaluating radiation delivered by a radiation beam output from a beam generator may include a phantom enclosing an internal volume and having an outer surface, extending around the internal volume, for exposure to radiation, and an inner surface coated, at least in part, with a scintillating material and facing the internal volume. The system may further include a camera external to the enclosed volume and configured to view at least a portion of the inner surface, through an opening of the hollow phantom, when radiated by the radiation beam. The system may further include at least one processor configured to receive images from the camera and calculate, based on the received images, a spatial dose distribution produced by the radiation delivered by the radiation beam to the hollow phantom.

Abstract: In accordance with the embodiments of the present disclosure, a rack comprising a frame having first vertical posts on a first side and second vertical posts on a second side, between which a plurality of RF amplifier modules are mounted, is provided. The RF power outputs of the RF amplifier modules are connected to inputs of an RF power combiner to deliver a combined RF power output. The RF power combiner is arranged at least partially in at least one of a first volume between the first vertical posts of the frame or a second volume between the second vertical posts of the frame, thereby reducing a footprint of the rack.

Abstract: A capsule for the transfer of a target material in a conveying system between a target irradiation station and a collecting station comprising: a beamline channel for the passage of an energetic beam irradiating the target material, a target holder holding the target material or a substrate backing the target material at a glancing angle with respect to the beamline channel axis, a degrader foil positioned across the beamline channel for degrading an energy of the energetic beam upstream of the target material, a target cooling inlet and a target cooling outlet for passage of a cooling fluid in a target cooling duct in a vicinity of the target holder such that the target material can be cooled during an irradiation, and a degrader foil cooling inlet and a degrader foil cooling outlet for passage of a cooling gas in a vicinity of the degrader foil.

Abstract: The invention relates to off-center detector X-ray tomography reconstruction of an image of an object on the basis of projection data acquired during a rotation of an X-ray source and the off-center detector around the object in two rotational passes of less than 360°, wherein a focus point of the X-ray beam travels along largely overlapping arcs (401, 402) in the two rotational passes, the off-center detector being positioned asymmetrically with respect to a central of the X-ray beam and a direction of a detector offset being reversed between the passes. According to the invention, redundancy weighting of the projection data with respect to a redundant acquisition of projection values during each of the rotational passes is made using a redundancy weighting function determined on the basis of a union of the arcs (401, 402).

Abstract: A synchrocyclotron for extracting charged particles accelerated to an extraction energy includes a magnetic unit comprising N valley sectors and N hill sectors, and configured for creating z-component of a main magnetic characterized by a radial tune of the successive orbits. The synchrocyclotron includes a first instability coil unit and a second instability coil unit configured for creating a field bump of amplitude increasing radially. The amplitude of the field bump may be varied to reach the value of the offset amplitude at the average instability onset radius. The offset amplitude may be the minimal amplitude of the field bump at the average instability onset radius required for sufficiently offsetting the center of the orbit of average instability onset radius to generate a resonance instability to extract the beam of charged particle at the average instability onset radius.

Abstract: A synchrocyclotron for extracting charged particles accelerated to an extraction energy includes a magnetic unit comprising N valley sectors and N hill sectors, and configured for creating z-component of a main magnetic characterized by a radial tune of the successive orbits. The synchrocyclotron includes a first instability coil unit and a second instability coil unit configured for creating a field bump of amplitude increasing radially. The amplitude of the field bump may be varied to reach the value of the offset amplitude at the average instability onset radius. The offset amplitude may be the minimal amplitude of the field bump at the average instability onset radius required for sufficiently offsetting the center of the orbit of average instability onset radius to generate a resonance instability to extract the beam of charged particle at the average instability onset radius.

Abstract: An electron accelerator including a resonant cavity, an electron source, an RF system, and at least one magnet unit is provided. The resonant cavity further includes a hollow closed conductor and the electron source is configured to radially inject a beam of electrons into the cavity. The RF system is configured to generate an electric field to accelerate the electrons along radial trajectories. The at least one magnet unit further-includes a deflecting magnet configured to generate a magnetic field that deflects an electron beam emerging out of the resonant cavity along a first radial trajectory and redirects the electron beam into the resonant cavity along a second radial trajectory. The resonant cavity further includes a first half shell, a second half shell, and a central ring element.

Abstract: A particle therapy system includes a particle accelerator for generating a charged particle beam, a beam delivery device, a beam transport system for transporting the beam from the particle accelerator to the beam delivery device, and a supporting device for supporting a subject. The beam delivery device is rotatable around the target and with respect to the supporting device, so as to be able to deliver the beam to the target according to a plurality of irradiation angles. The system also includes a controller configured to make the beam delivery device rotate at a beam-on speed and meanwhile to irradiate the target with the beam. The controller is configured to make the beam delivery device rotate at at least two different beam-on speeds with respect to the supporting device, a first speed corresponding to a first irradiation angle and a second speed corresponding to a second irradiation angle.

Abstract: The present disclosure relates to an apparatus for the synthesis of chemical compounds, e.g., radiopharmaceutical compounds. In one implementation, the apparatus may include a synthesis module and a loading module configured to receive multiple chemical cassettes having reagents and a transfer mechanism. The apparatus may further include a shifter configured to move the cassettes from a location on the loading module to a location connected to the synthesis module on an interface configured to connect to the cassette.

Abstract: The present disclosure relates to a particle therapy apparatus for irradiating a target with a charged particle beam. In one implementation, the apparatus includes an isocentric gantry rotatable about an axis and configured to direct a particle beam towards an isocenter of gantry and according to a final beam direction, a magnetic resonance imaging system configured to generate a main magnetic field parallel to the final beam direction, and a passive magnetic shield surrounding the magnetic resonance imaging system, the passive magnetic shield and the magnetic resonance imaging system being synchronously rotatable with the gantry about the axis.

Abstract: In accordance with the embodiments of the present disclosure, a rack comprising a frame having first vertical posts on a first side and second vertical posts on a second side, between which a plurality of RF amplifier modules are mounted, is provided. The RF power outputs of the RF amplifier modules are connected to inputs of an RF power combiner to deliver a combined RF power output. The RF power combiner is arranged at least partially in at least one of a first volume between the first vertical posts of the frame or a second volume between the second vertical posts of the frame, thereby reducing a footprint of the rack.

Abstract: The present invention relates to a particle therapy apparatus used for radiation therapy. More particularly, this invention relates to a gantry for delivering particle beams which comprises means to analyse the incoming beam. Means are integrated into the gantry to limit the momentum spread of the beam and/or the emittance of the beam.

Abstract: A cyclotron for accelerating a beam of charged particles and extracting the beam. The cyclotron includes a vacuum chamber; a target support element sealed and coupled to the vacuum chamber and including a tubular channel leading to a target; first energy specific extraction kit including a first stripper assembly with a stripper located at a first stripping position for stripping charged particles at a first energy and a second energy specific extraction kit for driving modified charged particles of second energy along a second extraction path towards a target holder, wherein the energy specific extraction kit includes: a second stripper assembly with a stripper located at a second stripping position for stripping charged particles at a second energy and an insert for modifying an orientation of the tubular channel to match the second extraction path such that the modified charged particles of second energy intercept the target holder.

Abstract: In accordance with the embodiments of the present disclosure, a rack comprising a frame having first vertical posts on a first side and second vertical posts on a second side, wherein the first side is opposite the second side, between which a plurality of RF amplifier modules are mounted, is provided. The RF power outputs of the RF amplifier modules are connected to inputs of an RF power combiner to deliver a combined RF power output. The RF power combiner is arranged at least partially in at least one of a first volume between the first vertical posts of the frame or a second volume between the second vertical posts of the frame, thereby reducing a footprint of the rack.

Abstract: This disclosure is related to an apparatus and method for commissioning or performing a quality assurance (QA) verification of a radiation therapy (RT) device. The device may comprise: (a) a motorised water phantom; (b) a RT controller configured for obtaining operation parameters of fields, and causing the RT device to emit a beam according to said operations parameters; (c) a QA controller having a memory for storing a measurements plan, the measurements plan including data defining a sequence of fields, and d) a reference radiation detector adapted and positioned for intercepting said radiation beam and for measuring the dose rate of said radiation beam. The reference radiation detector may be substantially transparent to the radiation beam. The QA controller may include an acquisition interface for acquiring and storing the dose rate from the reference radiation detector.

Abstract: A vario-energy electron accelerator includes a resonant cavity consisting of a closed conductor, an electron source injecting a beam of electrons into the resonant cavity, an RF system coupled to the resonant cavity and generating an electric field in the resonant cavity, magnet units centred on a mid-plane and generating a field in a deflecting chamber in fluid communication with the resonant cavity, the magnetic field deflecting along a first deflecting trajectory of adding length an electron beam exiting the resonant cavity along a first radial trajectory to reintroduce it into the resonant cavity along a second radial trajectory, an outlet for extracting along an extraction path an accelerated electron beam from the resonant cavity towards a target, wherein at least one of the magnet units is adapted for modifying the first deflecting trajectory to a second deflecting trajectory, allowing a variation of the energy of the electron beam.

Abstract: A sensing device for a radiation therapy apparatus, the apparatus comprising an accelerator and a beam-shaping device the beam shaping device being a multi-leaf collimator (MLC) (2) having a plurality of pairs of leaves, and a rotatable gantry, the sensing device comprising: a transmission electronic detector (1) comprising an array of ionization chambers. The ionization chambers are defined by a bias electrode (11a,11b, 34,42) on the one hand and by a planar array of conductive strips (40) or strip assemblies (30) on the other hand. The strips or strip assemblies are associated to the leaf pairs of the MLC. The strips are the collecting electrodes of the ionization chambers.

Abstract: A vario-energy electron accelerator includes a resonant cavity consisting of a closed conductor, an electron source injecting a beam of electrons into the resonant cavity, an RF system coupled to the resonant cavity and generating an electric field in the resonant cavity, magnet units centred on a mid-plane and generating a field in a deflecting chamber in fluid communication with the resonant cavity, the magnetic field deflecting along a first deflecting trajectory of adding length an electron beam exiting the resonant cavity along a first radial trajectory to reintroduce it into the resonant cavity along a second radial trajectory, an outlet for extracting along an extraction path an accelerated electron beam from the resonant cavity towards a target, wherein at least one of the magnet units is adapted for modifying the first deflecting trajectory to a second deflecting trajectory, allowing a variation of the energy of the electron beam.