Patents Assigned to Ion Beam Applications S.A.
  • Publication number: 20080023645
    Abstract: The present invention is related to an irradiation cell for producing a radioisotope of interest through the irradiation of a target material by a particle beam, comprising a metallic insert (2) forming a cavity (7) designed to house the target material and to be closed by an irradiation window, characterized in that said metallic insert (2) comprises at least two separate metallic parts (8,9) of different materials, being composed of at least a first part (8) comprising said cavity (7).
    Type: Application
    Filed: February 18, 2005
    Publication date: January 31, 2008
    Applicant: Ion Beam Applications, S.A.
    Inventors: Jean-Claude Amelia, Michel Ghyoot
  • Patent number: 7307264
    Abstract: An irradiation apparatus for irradiating by scanning a target volume according to a predetermined dose profile with a scanning beam of charged particles forming an irradiation spot on said target volume, said apparatus comprising: a beam generating device, a reference generator for computing, from said predetermined dose profile, through a dynamic inverse control strategy, the time evolution of commanded variables, these variables being the beam current I(t), the spot position settings x(t),y(t) and the scanning speed settings vx(t), vy(t), a monitor device having means for detecting at each time (t), the actual spot position as a measured position defined by the values xm(t),ym(t) on the target volume, characterised in that said irradiation apparatus further comprises means for determining the differences ex(t), ey(t) between the measured values xm(t), ym(t) and the spot position settings x(t) and y(t), and means for applying a correction to the scanning speed settings vx(t) and vy(t) depending on said d
    Type: Grant
    Filed: November 29, 2002
    Date of Patent: December 11, 2007
    Assignee: Ion Beam Applications S.A.
    Inventors: Caterina Brusasco, Bruno Marchand, Jean-François De Le Hoye, Damien Prieels
  • Patent number: 7289600
    Abstract: The present invention is related to process and an apparatus for irradiating products by means of high energy X-ray beam source (1) in an installation having an irradiation chamber (2), said process comprising the following steps, controlled by controlling means: determining the density of the products to be irradiated, in order to irradiate said products as a stack predetermining, on the basis of said density, the optimal size of the product stack able to optimize the throughput of the installation and/or the dose uniformity ratio (DUR), in the irradiation chamber (2), loading products as a stack onto rotation means (3) located in front of the X-ray beam source (1), while rotating the rotation means around a rotation axis (10), irradiating said products from a lateral side of said product stack.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: October 30, 2007
    Assignee: Ion Beam Applications S.A.
    Inventors: Arnold S. Herer, Fréderic Stichelbaut
  • Patent number: 7274026
    Abstract: The present invention is related to an apparatus for irradiating products conveyed on a pallet, comprising a beam source (3) for producing a radiation beam, a shielding wall (4) encompassing an irradiation chamber (2) and a revolving cylindrical door (6) having a recess (8) for holding said pallet, for bringing said pallet in and out of the irradiation chamber (2) wherein said high-energy radiation beam is directed towards a lateral side of said revolving door (6), for irradiating said pallet in said recess (8), or brought before said recess (8). The present invention is also related to a process wherein a product pallet is brought into an irradiation chamber (2) through a revolving cylindrical door (6) having a recess (8), and irradiated while in said recess (8) or in front of said recess (8).
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: September 25, 2007
    Assignee: Ion Beam Application S.A.
    Inventors: Jean-Louis Bol, Benoit Mullier, Fréderic Stichelbaut, Glenn Nelson
  • Patent number: 7197111
    Abstract: The present invention is related to a process for irradiation of a product pallet having four vertical faces by a photon beam such as an X-ray beam, a gamma source or similar, consisting in an irradiation procedure comprising the following steps: introducing the product pallet into an irradiation zone according to a horizontal translation movement, submitting said product pallet to said photon beam, the source of which having a vertical movement, the horizontal translation movement of the product pallet and the vertical movement of the beam resulting in the irradiation of a vertical face of said product pallet, moving out said product pallet from the irradiation zone. giving a rotation of substantially 90° to said product pallet using rotation means, repeating said irradiation process until at least the four vertical faces of said product pallet have been irradiated.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: March 27, 2007
    Assignee: Ion Beam Applications S.A.
    Inventors: Graham Rose, Muriel Vander Donckt, Frédéric Stichelbaut, Olivier Gregoire
  • Publication number: 20070009090
    Abstract: Method for irradiating in an irradiation chamber products being stored in the form of pallets or in the form of bulk material in appropriate containers by means of a high energy X-ray beam source, comprising the following steps: placing and arranging the products onto two different levels of products, so that a first set of products is placed on an upper level and a second set of products is placed on a lower level; irradiating both sets of products during a first period of time; submitting the products arranged on said two levels to a switch or transposition, so that the set of products arranged on an upper level is arranged on the lower level and vice-versa; irradiating during a second period of time the new arrangement formed of the two transposed sets of products.
    Type: Application
    Filed: June 29, 2006
    Publication date: January 11, 2007
    Applicant: ION BEAM APPLICATIONS, S.A.
    Inventors: Frederic Stichelbaut, Jean-Louis Bol
  • Publication number: 20060255285
    Abstract: The invention relates to a cyclotron which can produce a beam of accelerated charged particles that are intended for the irradiation of at least one target (200). The inventive cyclotron consists of a magnetic circuit which essentially comprises: an electromagnet with at least two poles (1, 1?), namely an upper pole (1) and a lower pole (1?), which are disposed symmetrically in relation to a mid-plane (110) which is perpendicular to the central axis (100) of the cyclotron and which are separated by a gap (120) containing the circulating charged particles and return flux (2) in order to close the aforementioned magnetic circuit; and a pair of main induction coils (5, 5?) which are used to create an essentially-constant main induction field in the gap between poles 1 and 1?.
    Type: Application
    Filed: November 14, 2003
    Publication date: November 16, 2006
    Applicant: Ion Beam Applications S.A.
    Inventors: Yves Jongen, Frederic Genin
  • Patent number: 7094472
    Abstract: The invention relates to ethylene polymers that are modified by ionizing radiation, prior to article formation, at a temperature less than the crystalline melt temperature and preferably under ambient atmosphere, as well as articles made from said polymers. The irradiated ethylene polymers exhibit enhanced melt strength, tensile strength, impact resistance, tear strength, adhesion to polar substances and thermal stability, decreased elongation, and lower melt flow index, but are easily processed and converted into and onto articles by conventional technologies including injection molding, extrusion, film and bottle blowing and powder coating.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: August 22, 2006
    Assignees: Ion Beam Applications, S.A., Gammatron Pty LTD
    Inventors: Tjaart Andries Du Plessis, Song Cheng, Horst Seute
  • Patent number: 7067827
    Abstract: The present invention is related to an apparatus and method for irradiating a product package, comprising a radiation source directing a radiation beam along a beam direction towards said product package, conveying means for transporting said product package past said radiation source along a transport path, and reflecting means located on at least one side of the plane formed by said beam direction and said transport path. By adjusting the distance and angle of the reflecting means to the conveyor and beam, and improved dose uniformity ratio is obtained.
    Type: Grant
    Filed: July 28, 2004
    Date of Patent: June 27, 2006
    Assignee: Ion Beam Applications S.A.
    Inventors: Jean Louis Bol, Olivier Gregoire, Francis Martin, Benoît Mullier, Frédéric Stichelbaut
  • Publication number: 20060104401
    Abstract: The present invention is related to a device and a method for producing a radioisotope of interest from a target fluid irradiated with a beam of accelerated charged particles, the device includes in a circulation circuit (17): an irradiation cell (1) having a metallic insert (2) able to form a cavity (8) designed to house the target fluid and closed by an irradiation window (7), the cavity (8) including at least one inlet (4) and at least one outlet (5); a pump (16) for circulating the target fluid inside the circulation circuit (17); an external heat exchanger (15); the pump (16) and the external heat exchanger (15) forming external cooling means of the target fluid; the device means for pressurizing (14) of the circulation circuit (17) and the external cooling means of the target fluid are arranged in such a way that the target fluid remains inside the cavity (8) essentially in the liquid state during the irradiation.
    Type: Application
    Filed: December 10, 2003
    Publication date: May 18, 2006
    Applicant: ION BEAM APPLICATIONS S.A.
    Inventors: Yves Jongen, Jozef Comor
  • Publication number: 20060106301
    Abstract: The present invention is related to a device for irradiating a patient with a charged particle beam, comprising a number of beam channels attached to a vertical wall, wherein a deflection magnet is present at the end of each channel. This deflection magnet is able to deflect the beam in the vertical plane over a given angle range. The couch whereon the patient is reclining is mobile in the vertical plane, so that the combined movement of the patient, and the variable deflection of the beam allow one point in the patient to be irradiated from several angles in the vertical plane.
    Type: Application
    Filed: April 30, 2003
    Publication date: May 18, 2006
    Applicant: ION BEAM APPLICATIONS S.A.
    Inventor: Mark Kats
  • Publication number: 20050269497
    Abstract: The invention concerns a cyclotron for accelerating a charged particle beam circulating in the median plane essentially in the form of two poles inducing a magnetic field and having a so-called axial injector, that is an injector arranged outside the cyclotron substantially along the main axis of the cyclotron and hence perpendicular to the median plane thereof and which is combined with deflecting means which enable the particle beam to be deflected until it is positioned in the median plane. The invention is characterized in that the deflecting means consist of a magnetic deflector.
    Type: Application
    Filed: July 18, 2003
    Publication date: December 8, 2005
    Applicant: Ion Beam Applications S.A.
    Inventor: Yves Jongen
  • Patent number: 6940944
    Abstract: The present invention is related to a method and apparatus of radiation processing of a product package in a device having a radiation source, a collimator having a variable aperture, and a turntable, said radiation processing resulting in a point in the product package where the dose is minimal (Dmin point) and a point in said product package where the dose is maximal (Dmax point) comprising the steps of: determining a first value of the collimator aperture, by increasing said aperture from a small value, where the Dmax point is located near the centre of the product package, up to a value where the Dmax point moves near to the centre of a small side of said package's rectangular horizontal cross-section; determining a second value of the collimator aperture, by further increasing the collimator aperture up to a point where the Dmin point moves from a point near the corner of the product package to the centre of said package; processing said package with radiation, the collimator aperture being kept at a
    Type: Grant
    Filed: September 8, 2003
    Date of Patent: September 6, 2005
    Assignee: Ion Beam Applications S. A.
    Inventor: Frederic Stichelbaut
  • Publication number: 20050121337
    Abstract: The present invention is related to a method and apparatuses for the electrodissolution of an element, in particular of fragments of an irradiated metallic target, comprising a fraction of a radio-isotope, for example Palladium-103. Besides the known steps of subjecting an electrolytic solution comprising the fragments to a voltage applied between two electrodes submerged in the solution, the method comprises the step of applying an external force to the solution in order to accumulate the fragments in the vicinity of one electrode, and thereby accelerate the dissolution process. The force applied may be centrifugal, or it may be a force obtained through a flow of the solution.
    Type: Application
    Filed: September 7, 2004
    Publication date: June 9, 2005
    Applicant: ION BEAM APPLICATIONS S.A.
    Inventor: Pierre Van Den Winkel
  • Publication number: 20050098740
    Abstract: The present invention is related to an apparatus and method for irradiating a product package, comprising a radiation source directing a radiation beam along a beam direction towards said product package, conveying means for transporting said product package past said radiation source along a transport path, and reflecting means located on at least one side of the plane formed by said beam direction and said transport path. By adjusting the distance and angle of the reflecting means to the conveyor and beam, and improved dose uniformity ratio is obtained.
    Type: Application
    Filed: July 28, 2004
    Publication date: May 12, 2005
    Applicant: ION BEAM APPLICATIONS S.A.
    Inventors: Jean Bol, Olivier Gregoire, Francis Martin, Benoit Mullier, Frederic Stichelbaut
  • Publication number: 20050069076
    Abstract: The invention relates to a method for production of a radio-isotope (4) from a target (3), containing a precursor (1) of said radio-isotope (4), using a beam of accelerated particles, comprising the following method steps: preparation of a target (3), containing the precursor (1) of the radioisotope (4), irradiation of said target (3) within an irradiation chamber (10) with a beam of accelerated particles in order to induce the transmutation of the precursor (1) into the radio-isotope (4), heating said target (3) in order to bring about the efflux of the radio-isotope (4) from the target (3), collection of said radio-isotope (4), extracted as a gas and condensation of said radio-isotope (4) into a solid or liquid. The invention further relates to a device for carrying out the above method and use of the device and method for the production of palladium 103 from rhodium 103.
    Type: Application
    Filed: June 21, 2004
    Publication date: March 31, 2005
    Applicant: ION BEAM APPLICATIONS S.A.
    Inventors: Ray Bricault, Stephane Lucas
  • Patent number: 6873123
    Abstract: The invention concerns a device (10) for regulating the intensity of a beam extracted from a particle accelerator, such as a cyclotron, used for example for protontherapy, said particles being generated from an ion source. The invention is characterized in that it comprises at least: a comparator (90) determining a difference ? between a digital signal IR representing the intensity of the beam measured at the output of the accelerator and a setpoint value IC of the beam intensity: a Smith predictor (80) which determines on the basis of the difference ?, a correct value of the intensity of the beam IP; an inverted correspondence table (40) supplying, on the basis of the corrected value of the intensity of the beam IP, a setpoint value IA for supply arc current from the ion source (20).
    Type: Grant
    Filed: June 3, 2002
    Date of Patent: March 29, 2005
    Assignee: Ion Beam Applications S.A.
    Inventors: Bruno Marchand, Bertrand Bauvir
  • Publication number: 20050053194
    Abstract: The present invention is related to a method and apparatus of radiation processing of a product package in a device having a radiation source, a collimator having a variable aperture, and a turntable, said radiation processing resulting in a point in the product package where the dose is minimal (Dmin point) and a point in said product package where the dose is maximal (Dmax point) comprising the steps of: determining a first value of the collimator aperture, by increasing said aperture from a small value, where the Dmax point is located near the centre of the product package, up to a value where the Dmax point moves near to the centre of a small side of said package's rectangular horizontal cross-section; determining a second value of the collimator aperture, by further increasing the collimator aperture up to a point where the Dmin point moves from a point near the corner of the product package to the centre of said package; processing said package with radiation, the collimator aperture being kept at a
    Type: Application
    Filed: September 8, 2003
    Publication date: March 10, 2005
    Applicant: ION BEAM APPLICATIONS S.A.
    Inventor: Frederic Stichelbaut
  • Publication number: 20040223870
    Abstract: The present invention is related to process and an apparatus for irradiating products by means of high energy X-ray beam source (1) in an installation having an irradiation chamber (2), said process comprising the following steps, controlled by controlling means:
    Type: Application
    Filed: March 18, 2004
    Publication date: November 11, 2004
    Applicant: ION BEAM APPLICATIONS S.A.
    Inventors: Arnold S. Herer, Frederic Stichelbaut
  • Patent number: 6806476
    Abstract: The instant invention is directed to an article irradiation facility that comprises, within a cell, an accelerator for generating a radiation beam and a beam pass conveyor. In order to better control the dose delivered to articles treated at the facility, the current of the radiation beam is slaved to the speed of the beam pass conveyor. The actual (versus requested) speed of the beam pass conveyor is continuously monitored using a variable frequency drive. The drive infers the speed of the beam pass conveyor from changes in the induction, resistance, flux current and/or inertia off the motor for the beam pass conveyor. The drive is positioned outside the cell and eliminates the need for speed sensors within the cell that are susceptible to radiation damage.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: October 19, 2004
    Assignee: Ion Beam Applications, S.A.
    Inventors: Graham Rose, Frank Joseph Groe