Abstract: A method of predicting parameters of an earthquake uses an array of ionosondes to scan an observed volume of an ionosphere located above a seismically active zone. The method includes monitoring ionograms provided by the array of ionosondes; detecting the presence of at least one seismic-induced irregularity (SII); determining a first predicted parameter corresponding to an epicenter location; and determining one or more predicted parameters selected from a group consisting of a magnitude, a time of occurrence, and a hypocenter depth. Algorithms for calculating the predicted parameters are presented in detail.