Patents Assigned to IONTAS LTD
  • BINDING MEMBERS WITH ALTERED DIVERSITY SCAFFOLD DOMAINS
    Publication number: 20190256840
    Abstract: This invention relates to libraries of binding members that each comprise a fusion protein which contains a donor diversity scaffold domain, such as a cysteine rich protein, inserted within a recipient diversity scaffold domain, such as an antibody constant or variable domain. Libraries and methods of generating libraries are provided, along with screening methods, binding members and methods of using the binding members.
    Type: Application
    Filed: January 9, 2017
    Publication date: August 22, 2019
    Applicant: IONTAS LTD
    Inventors: Aneesh Karatt Vellatt, John McCafferty, Sachin Surade, Tim Luetkens, Edward Masters, Michael Dyson