Patents Assigned to Iotek, Inc.
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Patent number: 6951533Abstract: The invention provides techniques for securely engaging an organ, such as a beating heart, with a manipulating device. A bag-like device may be deployed around a substantial volume of the organ and the manipulating device. In one embodiment, the bag-like device may be net-like, including one or more mesh apertures. Once deployed, the bag-like device cooperates with the manipulating device when the organ is manipulated and reduces the risk that the organ will be inadvertently released or dropped.Type: GrantFiled: February 4, 2002Date of Patent: October 4, 2005Assignee: Iotek, Inc.Inventor: Frederick J. Foley
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Patent number: 6773418Abstract: A device and method for delivering an agent to the uterine cervix make use of a seal member that defines a chamber upon engagement with the cervix. An agent delivery port in fluid communication with the chamber is provided for delivery of the agent to the uterine cervix. A vacuum port in fluid communication with the chamber allows application and retention of vacuum pressure to the chamber. At least a portion of the seal member can be made deformable in response to contact with the outer surface of the uterine cervix and application of vacuum pressure. Upon deformation, the seal member substantially seals the chamber against leakage of the agent. The seal member may include a skirt-like member that promotes adhesion of the seal member to the cervix, and enhances the effectiveness of the seal. The device facilitates vacuum application, cervical fixation, and a resulting barrier against uterine fluid leakage, providing an atraumatic, temporary cervical plug that remains effective while the vacuum is applied.Type: GrantFiled: August 18, 1999Date of Patent: August 10, 2004Assignee: Iotek, Inc.Inventors: James S. Sharrow, Thomas G. Adelman, Frederick J. Foley
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Publication number: 20040073206Abstract: Methods are provided to assist a surgeon in ablating conduction paths in tissue, such as a heart. In one embodiment, the invention presents a method that includes placing a guide in contact with the tissue to be ablated, applying an ablation probe to the tissue using the guide to assist in control of movement of the ablation probe, measuring the effectiveness of the ablation probe in ablation of the conduction paths, and deactivating the ablation probe when the measured effectiveness meets a desired level. Placement of the guide in contact with the tissue allows the surgeon to more easily sever the conduction path to form a lesion in a desired location.Type: ApplicationFiled: November 7, 2003Publication date: April 15, 2004Applicant: Iotek, Inc.Inventors: Frederick J. Foley, James S. Sharrow, Lorraine E. Reeve, Thomas G. Adelman, Michael F. Hoey
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Patent number: 6663622Abstract: Devices and a method are provided to assist a surgeon in ablating conduction paths in tissue, such as a heart. A device can be configured to operate as a template that adheres to the tissue surface, and allows the surgeon to more easily sever the conduction path to form a lesion in a desired location. In particular, the template can be used to guide the surgeon's use of a surgical instrument along a desired ablation path. In some case, the template may incorporate hardware that structurally supports the instrument for travel along the ablation path. A surgical instrument such as an ablation probe, e.g., radio frequency, laser, ultrasonic, microwave, thermal, chemical, mechanical, or cryogenic ablation probe, may be used to sever the conduction paths. Measurements made substantially contemporaneously with the conduction path ablation operation may be used to evaluate whether the desired degree of ablation has been achieved.Type: GrantFiled: August 28, 2000Date of Patent: December 16, 2003Assignee: Iotek, Inc.Inventors: Frederick J. Foley, James S. Sharrow, Lorraine E. Reeve, Thomas G. Adelman, Michael F. Hoey
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Patent number: 6641604Abstract: Devices and methods of manipulating and stabilizing organ tissue, such as heart tissue. The devices, which are of varying sizes, shapes and conformations, generally include a seal member having a chamber with a wall and a skirt-like member that extends outward from the chamber wall for contact with a surface of an organ. The skirt-like member is substantially compliant and tacky, thereby promoting adhesion with the organ surface. Adherence of the device to the tissue may be enhance by the mechanical or hydraulic application of vacuum pressure. The methods describe steps for manipulating, including moving, lifting, immobilizing, turning and reorienting, organ tissues. Additional methods describe steps for manipulating the heart.Type: GrantFiled: September 18, 2000Date of Patent: November 4, 2003Assignee: Iotek, Inc.Inventors: Thomas G. Adelman, Frederick J. Foley, James S. Sharrow, Lorraine E. Reeve, Michael F. Hoey
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Patent number: 6558314Abstract: Devices and methods of manipulating and stabilizing organ tissue, such as heart tissue. The devices, which are of varying sizes, shapes and conformations, generally include a seal member having a chamber with a wall and a skirt-like member that extends outward from the chamber wall for contact with a surface of an organ. The skirt-like member is substantially compliant and tacky, thereby promoting adhesion with the organ surface. Adherence of the device to the tissue may be enhance by the mechanical or hydraulic application of vacuum pressure. The methods describe steps for manipulating, including moving, lifting, immobilizing, turning and reorienting, organ tissues. Additional methods describe steps for manipulating the heart.Type: GrantFiled: October 19, 2000Date of Patent: May 6, 2003Assignee: Iotek, Inc.Inventors: Thomas G. Adelman, Frederick J. Foley, James S. Sharrow, Lorraine E. Reeve, Michael F. Hoey
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Patent number: 6139538Abstract: An apparatus for iontophoretically delivering an agent to a patient having a uterus and a cervix. The apparatus comprises a probe sized to fit within the cervical canal. A cervical cap has an inner surface. The probe projects from the inner surface. A first electrode has a first portion operably connected to the cervical cap and a second portion operably connected to the probe. The first electrode is configured to be electrically connected to a power supply. A second electrode is configured to be electrically connected to the power supply. A reservoir having a first portion operably connected to the cervical cap and a second portion operably connected to the probe.Type: GrantFiled: October 6, 1997Date of Patent: October 31, 2000Assignee: Iotek, Inc.Inventors: William C. Houghton, Keith R. Hildebrand, Martin B. Finkelstein, Frederick J. Foley
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Patent number: 6030375Abstract: The present invention is directed to a vaginal insert for delivering an agent to a urogenital tract in a patient. The patient has a vagina, and the vagina has a vaginal wall. The vaginal insert comprises a base member sized to fit within the vagina, the base member defines a chamber and a port in fluid communication with the chamber. A membrane is operatively connected to the base member. The membrane defines a reservoir and a pore. The reservoir is in fluid communication with the port. The membrane is sized so that the vaginal wall will exert pressure against the membrane when fluid is in the reservoir, thereby forcing some of the fluid to flow through the pore and to tissue of the urogenital tract.Type: GrantFiled: March 29, 1996Date of Patent: February 29, 2000Assignee: Iotek, Inc.Inventors: David W. Anderson, Robert E. Buuck, Arnold W. Thornton, Xiao Kang Zhang
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Patent number: 5988169Abstract: A vaginal insert and method for delivering an agent to a urogenital tract in a patient, the patient having a vagina, the vagina having anterior and posterior walls. The vaginal insert comprises a main portion and first and second portions operably connected to the main portion. The first and second portions each have an end projecting outward from the main portion, at least one of the projecting ends has means for containing the agent. The projecting ends of the first and second portions are configured to engage the anterior vaginal wall while the main portion engages the posterior vaginal wall, thereby positioning the projecting end of the first portion proximal to one side of the urogenital tract and positioning the projecting end of the second portion proximal to an opposite side of the urogenital tract.Type: GrantFiled: March 29, 1996Date of Patent: November 23, 1999Assignee: Iotek, Inc.Inventors: David W. Anderson, Robert E. Buuck, Arnold W. Thornton, Xiao Kang Zhang
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Patent number: 5861431Abstract: The present invention provides a method of treating incontinence in a patient that has a bladder and a urethra. The urethra forms a lumen for draining the bladder. The method comprises the steps of delivering an agent into the lumen and passing the agent from the lumen to internal body tissue. The agent increases restriction of the lumen thereby providing increased control over urine flow from the bladder.Type: GrantFiled: June 7, 1995Date of Patent: January 19, 1999Assignee: Iotek, Inc.Inventors: Keith R. Hildebrand, Jan Ellen O. Fowler, Dezso K. Levius
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Patent number: 5816248Abstract: A vaginal insert for delivering an agent to a urogenital tract in a patient. The patient has a vagina, and the vagina has an anterior wall. The vaginal insert comprises a member sized to fit within the vagina. The member has a surface defining a channel configured to engage the anterior vaginal wall and receive tissue proximal to the urethra. The member defines a chamber for retaining a supply of the agent and a plurality of delivery ports. At least some of the delivery ports are located along the channel. The plurality of delivery ports are in fluid communication with the chamber. The vaginal insert also comprises first and second electrodes. The first electrode is operably connected to the member. The first and second electrodes configured to be operably connected to a power source so that an electrical current can pass between the first and second electrodes and through tissue proximal the urethra.Type: GrantFiled: March 29, 1996Date of Patent: October 6, 1998Assignee: Iotek, Inc.Inventors: David W. Anderson, Robert E. Buuck, Arnold W. Thornton, Xiao Kang Zhang
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Patent number: 5749845Abstract: A method of delivering an agent to an organ from the group consisting of a bladder or a uterus. The method utilizes a catheter having an inflatable portion. The inflatable portion of the catheter is inserted into the organ and is inflated so that it expands the organ. The agent is then delivered from the inflatable portion into the wall of the organ. The agent may be prevented from escaping the organ.Type: GrantFiled: January 25, 1995Date of Patent: May 12, 1998Assignee: Iotek, Inc.Inventors: Keith R. Hildebrand, J. Edward Shapland
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Patent number: 5662582Abstract: An incontinence treatment plug includes a plug member which is sized to extend in an extended position into a urethra in sealing engagement. The plug member is originally everted. A force is applied to the plug member to force the plug member from an everted position into an extended position.Type: GrantFiled: February 27, 1995Date of Patent: September 2, 1997Assignee: Iotek, Inc,Inventors: Dezso K. Levius, David W. Anderson
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Patent number: 5640976Abstract: A rolling incontinence plug partially or fully inserted within a urethra has an anchor to restrict its insertion into the urethra. The anchor is configured to be placed between a vestibule and labia minora for restricting insertion of the incontinence plug. The outer circumference of the anchor easily conforms to the shape of the vestibule and responds to varying pressure of the labia minora as the patient moves. Further, because the anchor naturally conforms to the vestibule, no additional artificial substances or devices are needed to secure the anchor.Type: GrantFiled: June 6, 1995Date of Patent: June 24, 1997Assignee: Iotek, Inc.Inventor: Dezso K. Levius
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Patent number: 5513659Abstract: An incontinence plug includes an anchor for positioning within a patient's bladder and a flow blocking enlargement for acting in sealing engagement against a urethral wall. A protective sleeve prevents contact between the distal end of the plug and an entrance end of the urethra to prevent transportation of pathogens from the entrance of the urethra toward the bladder.Type: GrantFiled: March 20, 1995Date of Patent: May 7, 1996Assignee: Iotek, Inc.Inventors: Robert E. Buuck, Dezso K. Levius