Abstract: Disclosed are compounds having a monoterpenoid and/or phenylpropanoid moiety and methods of their making and use as pesticidal compounds, such as herbicides.
Type:
Grant
Filed:
August 23, 2017
Date of Patent:
February 4, 2025
Assignees:
Kittrich Corporation, Iowa State University Foundation, Inc.
Inventors:
Joel R. Coats, James S. Klimavicz, Edmund J. Norris, Steven M. Bessette, A. David Lindsay
Abstract: The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs against viral infection or postweaning multisystemic wasting syndrome (PMWS) caused by PCV2. The new chimeric infectious DNA clone and its derived, avirulent chimeric virus are constructed from the nonpathogenic PCV1 in which the immunogenic ORF gene of the pathogenic PCV2 replaces a gene of the nonpathogenic PCV1, preferably in the same position. The chimeric virus advantageously retains the nonpathogenic phenotype of PCV1 but elicits specific immune responses against the pathogenic PCV2. The invention further embraces the immunogenic polypeptide expression products. In addition, the invention encompasses two mutations in the PCV2 immunogenic capsid gene and protein, and the introduction of the ORF2 mutations in the chimeric clones.
Type:
Grant
Filed:
November 13, 2015
Date of Patent:
February 13, 2018
Assignees:
Virginia Tech Intellectual Properties, Inc., Iowa State University Foundation, Inc.
Inventors:
Xiang-Jin Meng, Martijn Fenaux, Patrick G. Halbur
Abstract: Disclosed herein are novel alleles characterized by polymorphisms in the CAST gene. The alleles may be used to genetically type animals. In a preferred embodiment, the alleles may be used as markers for animal meat quality and/or growth. Methods for identifying such markers, and methods of screening animals to determine those more likely to produce desired meat quality and/or growth and preferably selecting those animals for future breeding purposes are also disclosed.